ARRDC1 (NM_152285) Human Untagged Clone
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | ARRDC1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | ECoRI-NOT | |
| ACCN | NM_152285 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_152285.2, NP_689498.1 |
| RefSeq Size | 1621 bp |
| RefSeq ORF | 1302 bp |
| Locus ID | 92714 |
| UniProt ID | Q8N5I2 |
| Cytogenetics | 9q34.3 |
| Domains | arrestin |
| Summary | Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_152285" in other vectors (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC207160 | ARRDC1 (Myc-DDK-tagged)-Human arrestin domain containing 1 (ARRDC1) | 10 ug |
$457.00
|
|
| RC207160L3 | Lenti ORF clone of Human arrestin domain containing 1 (ARRDC1), Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC207160L4 | Lenti ORF clone of Human arrestin domain containing 1 (ARRDC1), mGFP tagged | 10 ug |
$757.00
|
|
| RG207160 | ARRDC1 (tGFP-tagged) - Human arrestin domain containing 1 (ARRDC1) | 10 ug |
$657.00
|
|
| SC100561 | ARRDC1 (untagged)-Human arrestin domain containing 1 (ARRDC1) | 10 ug |
$457.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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