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Complement C7 (C7) (NM_000587) Human Untagged Clone

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SKU
SC322733
C7 (untagged)-Human complement component 7 (C7)
  $773.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol Complement C7
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for SC322733 GGCAGCCTGCTGGGCTCTTCCTGCTGTTGAAAACTTACCCGGCCCTTACAGAGGAAATCT
TCCTCCTCTCTTCTGCCCTGAATGTTTTCCCAAACATGAAGGTGATAAGCTTATTCATTT
TGGTGGGATTTATAGGAGAGTTCCAAAGTTTTTCAAGTGCCTCCTCTCCAGTCAACTGCC
AGTGGGACTTCTATGCCCCTTGGTCAGAATGCAATGGCTGTACCAAGACTCAGACTCGCA
GGCGGTCAGTTGCTGTGTATGGGCAGTATGGAGGCCAGCCTTGTGTTGGAAATGCTTTTG
AAACACAGTCCTGTGAACCTACAAGAGGATGTCCAACAGAGGAGGGATGTGGAGAGCGTT
TCAGGTGCTTTTCAGGTCAGTGCATCAGCAAATCATTGGTTTGCAATGGGGATTCTGACT
GTGATGAAGACAGTGCTGATGAAGACAGATGTGAGGACTCAGAAAGGAGACCTTCCTGTG
ATATCGATAAACCTCCTCCTAACATAGAACTTACTGGAAATGGTTACAATGAACTCACTG
GCCAGTTTAGGAACAGAGTCATCAATACCAAAAGTTTTGGTGGTCAATGTAGAAAGGTGT
TTAGTGGGGATGGAAAAGATTTCTACAGGCTGAGTGGAAATGTCCTGTCCTATACATTCC
AGGTGAAAATAAATAATGATTTTAATTATGAATTTTACAATAGTACTTGGTCTTATGTAA
AACATACGTCGACAGAACACACATCATCTAGTCGGAAGCGCTCCTTTTTTAGATCTTCAT
CATCTTCTTCACGCAGTTATACTTCACATACCAATGAAATCCATAAAGGAAAGAGTTACC
AACTGCTGGTTGTTGAGAACACTGTTGAAGTGGCTCAGTTCATTAATAACAATCCAGAAT
TTTTACAACTTGCTGAGCCATTCTGGAAGGAGCTTTCCCACCTCCCCTCTCTGTATGACT
ACAGTGCCTACCGAAGATTAATCGACCAGTACGGGACACATTATCTGCAATCTGGGTCGT
TAGGAGGAGAATACAGAGTTCTATTTTATGTGGACTCAGAAAAATTAAAACAAAATGATT
TTAATTCAGTCGAAGAAAAGAAATGTAAATCCTCAGGTTGGCATTTTGTCGTTAAATTTT
CAAGTCATGGATGCAAGGAACTGGAAAACGCTTTAAAAGCTGCTTCAGGAACCCAGAACA
ATGTATTGCGAGGAGAACCGTTCATCAGAGGGGGAGGTGCAGGCTTCATATCTGGCCTTA
GTTACCTAGAGCTGGACAATCCTGCTGGAAACAAAAGGCGATATTCTGCCTGGGCAGAAT
CTGTGACTAATCTTCCTCAAGTCATAAAACAAAAGCTGACACCTTTATATGAGCTGGTAA
AGGAAGTACCTTGTGCCTCTGTGAAAAAACTATACCTGAAATGGGCTCTTGAAGAGTATC
TGGATGAATTTGACCCCTGTCATTGCCGGCCTTGTCAAAATGGTGGTTTGGCTACTGTTG
AGGGGACCCATTGTCTGTGCCATTGCAAACCGTACACATTTGGTGCGGCGTGTGAGCAAG
GAGTCCTCGTAGGGAATCAAGCAGGAGGGGTTGATGGAGGTTGGAGTTGCTGGTCCTCTT
GGAGCCCCTGTGTCCAAGGGAAGAAAACAAGAAGCCGTGAATGCAATAACCCACCTCCCA
GTGGGGGTGGGAGATCCTGCGTTGGAGAAACGACAGAAAGCACACAATGCGAAGATGAGG
AGCTGGAGCACTTGAGGTTGCTTGAACCACATTGCTTTCCTTTGTCTTTGGTTCCAACAG
AATTCTGTCCATCACCTCCTGCCTTGAAAGATGGATTTGTTCAAGATGAAGGTACAATGT
TTCCTGTGGGGAAAAATGTAGTGTACACTTGCAATGAAGGATACTCTCTTATTGGAAACC
CAGTGGCCAGATGTGGAGAAGATTTACGGTGGCTTGTTGGGGAAATGCATTGTCAGAAAA
TTGCCTGTGTTCTACCTGTACTGATGGATGGCATACAGAGTCACCCCCAAAAACCTTTCT
ACACAGTTGGTGAGAAGGTGACTGTTTCCTGTTCAGGTGGCATGTCCTTAGAAGGTCCTT
CAGCATTTCTCTGTGGCTCCAGCCTTAAGTGGAGTCCTGAGATGAAGAATGCCCGCTGTG
TACAAAAAGAAAATCCGTTAACACAGGCAGTGCCTAAATGTCAGCGCTGGGAGAAACTGC
AGAATTCAAGATGTGTTTGTAAAATGCCCTACGAATGTGGACCTTCCTTGGATGTATGTG
CTCAAGATGAGAGAAGCAAAAGGATACTGCCTCTGACAGTTTGCAAGATGCATGTTCTCC
ACTGTCAGGGTAGAAATTACACCCTTACTGGTAGGGACAGCTGTACTCTGCCTGCCTCAG
CTGAGAAAGCTTGTGGTGCCTGCCCACTGTGGGGAAAATGTGATGCTGAGAGCAGCAAAT
GTGTCTGCCGAGAAGCATCGGAGTGCGAGGAAGAAGGGTTTAGCATTTGTGTGGAAGTGA
ACGGCAAGGAGCAGACGATGTCTGAGTGTGAGGCGGGCGCTCTGAGATGCAGAGGGCAGA
GCATCTCTGTCACCAGCATAAGGCCTTGTGCTGCGGAAACCCAGTAGGCTCCTGGAGGCC
CTGGTCAGCTTGCTTGGAATCCAGCAGGCAGCTGGGGCTGAGTGAAAACATCTGCACAAC
TGGGCACTGGACAGCTTTTCCTTCTTCTCCAGTGTCTACCTTCCTCCTCAACTCCCAGCC
ATCTGTATAAACACAATCCTTTGTTCTCCCAAATCTGAATCGAATTACTCTTTTGCCTCC
TTTTTAATGTCAGTAAGGATATGAGCCTTTGCACAGGCTGGCTGCGTGTTCTTGAAATAG
GTGTTACCTTCTCTGGGCCTTGGTTTTTTAAAATCTGTAAAATTAGAGGATTGCACTAGA
GAAACTTGAATGCTCCATTCAGGCCTATCATTTTATTAAGTATGATTGACACAGCCCATG
GGCCAGAACACACTCTACAAAATGACTAGGATAACAGAAAGAACGTGATCTCCTGATTAG
AGAGGGTGGTTTTCCTCAATGGAACCAAATATAAAGAGGACTTGAACAAAAATGACAGAT
ACAAACTATTTCTATCCTGAGTAGTAATCTCACACTTCATCCTATAGAGTCAACCACCAC
AGATAGGAATTCCTTATTCTTTTTTTAATTTTTTTAAGACAGAGTCTCACTTTGTTGCCC
AGGCTGGAGCGCAGTGGGGTGATCTCATCTCCCTGCAACCTCCGCCTCCTGGGTTCAAGC
GATTCTTGTGCCTCAGCTTCCCAAGCAGCTGGGATTACAGGTGCCCGCCACCACGCCCAG
CTAATTTTTGCATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCACGCTCGTCTCCAA
CTCCTGACCTCAGGTAATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATG
AACCACCACGCCTGGCTGGAATACTTACTCTTGTCGGGAGATTGAACCACTAAAATGTTA
GAGCAGAATTCATTATGCTGTGGTCACAGGGGTGTCTTGTCTGAGAACAAATACAATTCA
GTCTTCTCTTTGGGGTTTTAGTATGTGTCAAACATAGGACTGGAAGTTTGCCCCTGTTCT
TTTTTCTTTTGAAAGAACATCAGTTCATGCCTGAGGCATGAGTGACTGTGCATTTGAGAA
TAGTTTTCCCTATTCTGTGGATACAGTCCCAGAGTTTTCAGGGAGTACACAGGTAGATTA
GTTTGAAGCATTGACCTTTTATTTATTCCTTATTTCTCTTTCATCAAAACAAAACAGCAG
CTGTGGGAGGAGAAATGAGAGGGCTTAAATGAAATTTAAAATAAGCTATATTATACAAAT
ACTATCTCTGTATTGTTCTGACCCTGGTAAATATATTTCAAAACTTCAGATGACAAGGAT
TAGAACACTCATTAAAGATGCTATTCTTCAGAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_000587
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_000587.2, NP_000578.2
RefSeq Size 4034 bp
RefSeq ORF 2532 bp
Locus ID 730
UniProt ID P10643
Cytogenetics 5p13.1
Domains CCP, FIMAC, ldl_recept_a, MACPF, tsp_1
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
Summary This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. provided by RefSeq, Nov 2016
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Documents
Resources
"NM_000587" in other vectors (5)
SKU Description Size Price
RC209562 C7 (Myc-DDK-tagged)-Human complement component 7 (C7) 10 ug
$772.00
RC209562L3 Lenti ORF clone of Human complement component 7 (C7), Myc-DDK-tagged 10 ug
$1,072.00
RC209562L4 Lenti ORF clone of Human complement component 7 (C7), mGFP tagged 10 ug
$1,072.00
RG209562 C7 (tGFP-tagged) - Human complement component 7 (C7) 10 ug
$789.00 $972.00
SC119808 C7 (untagged)-Human complement component 7 (C7) 10 ug
$773.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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