ASCC1 (NM_015947) Human Untagged Clone

SKU
SC322320
ASCC1 (untagged)-Human activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 3
  $457.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol ASCC1
Synonyms ASC1p50; CGI-18; RP11-150D20.4
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for SC322320 AGAGAACGCGCTCGCGTAGAGGAATTCCGGGTCCTCCTCCTCGCCCTACCTTGGTTTACC
TGCAGCCGCCTAGTCCTCTTCTCCTTCTCTTTGATGATTCAGGGCCTCGGCTTCCCTCAC
GGGCATAATTGGAATATCATTTGGAGAAAGTGTCATGGAAGTTCTGCGTCCACAGCTTAT
AAGAATTGATGGCCGGAATTACAGGAAGAATCCAGTCCAAGAACAGACCTATCAACATGA
AGAAGATGAAGAGGACTTCTATCAAGGCTCCATGGAGTGTGCTGATGAGCCCTGTGATGC
CTACGAGGTGGAGCAGACCCCACAAGGATTCCGGTCTACTTTGAGGGCCCCCAGCTTGCT
CTATAAGCATATAGTTGGAAAGAGAGGGGACACTAGGAAGAAAATAGAAATGGAGACCAA
AACTTCTATTAGCATTCCTAAACCTGGACAAGACGGGGAAATTGTAATCACTGGCCAGCA
TCGAAATGGTGTAATTTCAGCCCGAACACGGATTGATGTTCTTTTGGACACTTTTCGAAG
AAAGCAGCCCTTCACTCACTTCCTTGCCTTTTTCCTCAATGAAGTTGAGGTTCAGGAAGG
ATTCCTGAGATTCCAGGAGGAAGTACTGGCGAAGTGCTCCATGGATCATGGGGTTGACAG
CAGCATTTTCCAGAATCCTAAAAAGCTTCATCTAACTATTGGGATGTTGGTGCTTTTGAG
TGAGGAAGAGATCCAGCAGACATGTGAGATGCTACAGCAGTGTAAAGAGGAATTCATTAA
TGATATTTCTGGGGGTAAACCCCTAGAAGTGGAGATGGCAGGGATAGAATACATGAATGA
TGATCCTGGCATGGTGGATGTTCTTTACGCCAAAGTCCATATGAAAGATGGCTCCAACAG
GCTACAAGAATTAGTTGATCGAGTGCTGGAACGTTTTCAGGCATCTGGACTAATAGTGAA
AGAGTGGAATAGTGTGAAACTGCATGCTACAGTTATGAATACACTATTCAGGAAAGACCC
CAATGCTGAAGGCAGGTACAATCTCTACACAGCGGAAGGCAAATATATCTTCAAGGAAAG
AGAATCATTTGATGGCCGAAATATTTTAAAGTTGTTTGAGAACTTCTACTTTGGCTCCCT
AAAGCTGAATTCAATTCACATCTCTCAGAGGTTCACCGTAGACAGCTTTGGAAACTACGC
TTCCTGTGGACAAATTGACTTCTCCTGAGGTGGATCTTGGAAAGCACTAGAAACTAAACA
TCTTCACCAGGTGCTGAAGAAAAGTGTCTTCGTTTTAATTGCCAAGCAGGGATGTGGACA
TTTGGATGGTGACTTCCCTGGGTGGTTCCCCATAGATTCACCATTGCCTCTAATGGTGTC
TACACCCGTCATACTACCAGCTGAGATGGTGGTGGGCATAAGGAGAATTTGTGCCTATAA
CCCTTAGTGTGTTCTGGTTTTTTTTCTTTTAATTTTTAAATTGTCGTAAAATACTCATAA
AACATACTGTCTTCACCATTTTTAAGTGCACAGTTCAGTAACGTTAACTGTTAATACATT
CATAATGCTGTGTGGCCGTCACCGCCGTCCATCTCCATAGGCTTCTCAGCTTGTAAAATG
GAAACTGTACCCATTAAACAGTAATTCCCACTCCTCCCAGAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_015947
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_015947.2, NP_057031.2
RefSeq Size 2090 bp
RefSeq ORF 1074 bp
Locus ID 51008
Cytogenetics 10q22.1
Domains KH
Summary This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. provided by RefSeq, Dec 2011
Transcript Variant: This variant (3) differs in both UTRs and has multiple coding region differences compared to variant 1, one of which results in a frameshift. The resulting isoform (b) has a distinct C-terminus and is shorter than isoform a. Variants 2, 3, and 4 all encode the same isoform (b).
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Documents
Resources
"NM_015947" in other vectors (4)
SKU Description Size Price
RC201872 ASCC1 (Myc-DDK-tagged)-Human activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 3 10 ug
$457.00
RC201872L3 Lenti ORF clone of Human activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 3, Myc-DDK-tagged 10 ug
$757.00
RC201872L4 Lenti ORF clone of Human activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 3, mGFP tagged 10 ug
$757.00
RG201872 ASCC1 (tGFP-tagged) - Human activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 3 10 ug
$657.00

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