NSMCE4A (NM_017615) Human Untagged Clone

SKU
SC321141
NSMCE4A (untagged)-Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1
  $457.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol NSMCE4A
Synonyms C10orf86; NS4EA; NSE4A
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites Please inquire |
ACCN NM_017615
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_017615.1, NP_060085.1
RefSeq Size 1387 bp
RefSeq ORF 1158 bp
Locus ID 54780
UniProt ID Q9NXX6
Cytogenetics 10q26.13
Summary Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_017615" in other vectors (5)
SKU Description Size Price
RC209357 NSMCE4A (Myc-DDK-tagged)-Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1 10 ug
$289.00 $1,098.00
RC209357L3 Lenti ORF clone of Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1, Myc-DDK-tagged 10 ug
$1,398.00
RC209357L4 Lenti ORF clone of Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1, mGFP tagged 10 ug
$1,398.00
RG209357 NSMCE4A (tGFP-tagged) - Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1 10 ug
$1,298.00
SC114098 NSMCE4A (untagged)-Human non-SMC element 4 homolog A (S. cerevisiae) (NSMCE4A), transcript variant 1 10 ug
$457.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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