GDAP1L1 (NM_024034) Human Untagged Clone

SKU SC320647

GDAP1L1 (untagged)-Human ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: GDAP1L1
• Synonyms: dJ881L22.1; dJ995J12.1.1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024034.3 GAGAGCCGCCGCGCCGGAGCCTCCTTCTTTCCTGCCTCTGATTCCGGGCTGTCATGGCGA; CCCCCAACAATCTGACCCCCACCAACTGCAGCTGGTGGCCCATCTCCGCGCTGGAGAGCG; ATGCGGCCAAGCCAGCGGAGGCCCCCGACGCTCCCGAGGCGGCCAGCCCCGCCCATTGGC; CCAGGGAGAGCCTGGTTCTGTACCACTGGACCCAGTCCTTCAGCTCGCAGAAGGTGCGGC; TGGTGATCGCCGAGAAGGGCCTGGTGTGCGAGGAGCGGGACGTGAGCCTGCCACAGAGCG; AGCACAAGGAGCCCTGGTTCATGCGGCTCAACCTGGGCGAGGAGGTGCCCGTCATCATCC; ACCGCGACAACATCATCAGTGACTATGACCAGATCATTGACTATGTGGAGCGCACCTTCA; CAGGAGAGCACGTGGTGGCCCTGATGCCCGAGGTGGGCAGCCTGCAGCACGCACGGGTGC; TGCAGTACCGGGAGCTGCTGGACGCACTGCCCATGGATGCCTACACGCATGGCTGCATCC; TGCATCCCGAGCTCACCACCGACTCCATGATCCCCAAGTACGCCACGGCCGAGATCCGCA; GACATTTAGCCAATGCCACCACGGACCTCATGAAACTGGACCATGAAGAGGAGCCCCAGC; TCTCCGAGCCCTACCTTTCTAAACAAAAGAAGCTCATGGCCAAGATCTTGGAGCATGATG; ATGTGAGCTACCTGAAGAAGATCCTCGGGGAACTGGCCATGGTGCTGGACCAGATTGAGG; CGGAGCTGGAGAAGAGGAAGCTGGAGAACGAGGGGCAGAAATGCGAGCTGTGGCTCTGTG; GCTGTGCCTTCACCCTCGCTGATGTCCTCCTGGGAGCCACCCTGCACCGCCTCAAGTTCC; TGGGACTGTCCAAGAAATACTGGGAAGATGGCAGCCGGCCCAACCTGCAGTCCTTCTTTG; AGAGGGTCCAGAGACGCTTTGCCTTCCGGAAAGTCCTGGGTGACATCCACACCACCCTGC; TGTCGGCCGTCATCCCCAATGCTTTCCGGCTGGTCAAGAGGAAACCCCCATCCTTCTTCG; GGGCGTCCTTCCTCATGGGCTCCCTGGGTGGGATGGGCTACTTTGCCTACTGGTACCTCA; AGAAAAAATACATCTAGGGCCAGGCCTGGGGCTTGGTGTCTGAAAAAAAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_024034
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024034.3, NP_076939.3
• RefSeq Size: 2244 bp
• RefSeq ORF: 1104 bp
• Locus ID: 78997
• UniProt ID: Q96MZ0
• Cytogenetics: 20q13.12
• Protein Families: Transmembrane
• Summary: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]; Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.