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PAK4 (NM_001014831) Human Untagged Clone

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SKU
SC320565
PAK4 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2
  $551.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol PAK4
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_001014831.2 GCGGGAGTGTCCGCGGTGGTGGCGGTGCAAGAGAGCTGAGGGAGGCGCGAGGGCGCGGAG
TTCCAGGTCGAGCAGTTAGGCCGCGAGCGACTGCGGCGCCGAGCCGATGAGTAACCCGAA
GCCCCTAGAGGAGTGGTCACCTGCCTGAGGGCACTTCTGTCCCACCAGCATCAGACCAGG
TGTGTGCAGGCTCTCTATGGGATGCCGCCATCAGAATGTCTCTTCCTCAGCCCCTTTGTT
TTTTAAAGTGGCTTTGGTCGACCATTTGCTCTGTGCTTGGTACTGTGTCAAGGGCCCGAT
TGAAGACCACAGATCCTAAAGATAGGGGAGTGTCGCGACAAGGCTGCCTGGGGTGCCCTC
TTAACCCAGGGGATCAGTAACCCTGTGCTGAGTCAATATCCAAAGGCCGCACCGAGTCCC
CGGCACCATGTTTGGGAAGAGGAAGAAGCGGGTGGAGATCTCCGCGCCGTCCAACTTCGA
GCACCGCGTGCACACGGGCTTCGACCAGCACGAGCAGAAGTTCACGGGGCTGCCCCGCCA
GTGGCAGAGCCTGATCGAGGAGTCGGCTCGCCGGCCCAAGCCCCTCGTCGACCCCGCCTG
CATCACCTCCATCCAGCCCGGGGCCCCCAAGACCATCGTGCGGGGCAGCAAAGGTGCCAA
AGATGGGGCCCTCACGCTGCTGCTGGACGAGTTTGAGAACATGTCGGTGACACGCTCCAA
CTCCCTGCGGAGAGACAGCCCGCCGCCGCCCGCCCGTGCCCGCCAGGAAAATGGGATGCC
AGAGGAGCCGGCCACCACGGCCAGAGGGGGCCCAGGGAAGGCAGGCAGCCGAGGCCGGTT
CGCCGGTCACAGCGAGGCGGGTGGCGGCAGTGGTGACAGGCGACGGGCGGGGCCAGAGAA
GAGGCCCAAGTCTTCCAGGGAGGGCTCAGGGGGTCCCCAGGAGTCCTCCCGGGACAAACG
CCCCCTCTCCGGGCCTGATGTCGGCACCCCCCAGCCTGCTGGTCTGGCCAGTGGGGCGAA
ACTGGCAGCTGGCCGGCCCTTTAACACCTACCCGAGGGCTGACACGGACCACCCATCCCG
GGGTGCCCAGGGGGAGCCTCATGACGTGGCCCCTAACGGGCCATCAGCGGGGGGCCTGGC
CATCCCCCAGTCCTCCTCCTCCTCCTCCCGGCCTCCCACCCGAGCCCGAGGTGCCCCCAG
CCCTGGAGTGCTGGGACCCCACGCCTCAGAGCCCCAGCTGGCCCCTCCAGCCTGCACCCC
CGCCGCCCCTGCTGTTCCTGGGCCCCCTGGCCCCCGCTCACCACAGCGGGAGCCACAGCG
AGTATCCCATGAGCAGTTCCGGGCTGCCCTGCAGCTGGTGGTGGACCCAGGCGACCCCCG
CTCCTACCTGGACAACTTCATCAAGATTGGCGAGGGCTCCACGGGCATCGTGTGCATCGC
CACCGTGCGCAGCTCGGGCAAGCTGGTGGCCGTCAAGAAGATGGACCTGCGCAAGCAGCA
GAGGCGCGAGCTGCTCTTCAACGAGGTGGTAATCATGAGGGACTACCAGCACGAGAATGT
GGTGGAGATGTACAACAGCTACCTGGTGGGGGACGAGCTCTGGGTGGTCATGGAGTTCCT
GGAAGGAGGCGCCCTCACCGACATCGTCACCCACACCAGGATGAACGAGGAGCAGATCGC
GGCCGTGTGCCTTGCAGTGCTGCAGGCCCTGTCGGTGCTCCACGCCCAGGGCGTCATCCA
CCGGGACATCAAGAGCGACTCGATCCTGCTGACCCATGATGGCAGGGTGAAGCTGTCAGA
CTTTGGGTTCTGCGCCCAGGTGAGCAAGGAAGTGCCCCGAAGGAAGTCGCTGGTCGGCAC
GCCCTACTGGATGGCCCCAGAGCTCATCTCCCGCCTTCCCTACGGGCCAGAGGTAGACAT
CTGGTCGCTGGGGATAATGGTGATTGAGATGGTGGACGGAGAGCCCCCCTACTTCAACGA
GCCACCCCTCAAAGCCATGAAGATGATTCGGGACAACCTGCCACCCCGACTGAAGAACCT
GCACAAGGTGTCGCCATCCCTGAAGGGCTTCCTGGACCGCCTGCTGGTGCGAGACCCTGC
CCAGCGGGCCACGGCAGCCGAGCTGCTGAAGCACCCATTCCTGGCCAAGGCAGGGCCGCC
TGCCAGCATCGTGCCCCTCATGCGCCAGAACCGCACCAGATGAGGCCCAGCGCCCTTCCC
CTCAACCAAAGAGCCCCCCGGGTCACCCCCGCCCCACTGAGGCCAGTAGGGGGCCAGGCC
TCCCACTCCTCCCAGCCCGGGAGATGCTCCGCGTGGCACCACCCTCCTTGCTGGGGGTAG
ATGAGACCCTACTACTGAACTCCAGTTTTGATCTCGTGACTTTTAGAAAAACACAGGGAC
TCGTGGGAGCAAGCGAGGCTCCCAGGACCCCCACCCTCTGGGACAGGCCCTCCCCCATGT
TCTTCTGTCTCCAGGAAGGGCAGCGGCCCTCCCATCACTGGAAGTCTGCAGTGGGGGTCG
CTGGGGGTGGAGAGAACACTAAGAGGTGAACATGTATGAGTGTGTGCACGCGTGTGAGTG
TGCATGTGTGTGTGTGCAAAGGTCCAGCCACCCCGTCCTCCAGCCTGCAAGGGGTGTCTG
GCGCCTTGCCTGACACCCAGCCCCCTCTCCCCCTGAGCCATTGTGGGGGTCGATCATGAA
TGTCCGAAGAGTGGCCTTTTCCCGTAGCCCTGCGCCCCCTTTCTGTGGCTGGATGGGGAG
ACAGGTCAGGGCCCCCCACCCTCTCCAGCCCCTGCAGCAAATGACTACTGCACCTGGACA
GCCTCCTCTTTTCTAGAAGTCTATTTATATTGTCATTTTATAACACTCTAGCCCCTGCCC
TTATTGGGGGACAGATGGTCCCTGTCCTGCGGGGTGGCCCTGGCAGAACCACTGCCTGAA
GAACCAGGTTCCTGCCCGGTCAGCGCAGCCCCAGCCCGCCCACCCCTGCCTCGAGTTAGT
TTTACAATTAAAACATTGTCTTGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_001014831
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001014831.2, NP_001014831.1
RefSeq Size 3064 bp
RefSeq ORF 1776 bp
Locus ID 10298
UniProt ID O96013
Cytogenetics 19q13.2
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
Summary PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) has an additional segment in the 5' UTR, and encodes the same isoform (1), as compared to variant 1.
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"NM_001014831" in other vectors (7)
SKU Description Size Price
RC206847 PAK4 (Myc-DDK-tagged)-Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2 10 ug
$550.00
RC206847L1 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2, Myc-DDK-tagged 10 ug
$850.00
RC206847L2 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2, mGFP tagged 10 ug
$850.00
RC206847L3 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2, Myc-DDK-tagged 10 ug
$850.00
RC206847L4 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2, mGFP tagged 10 ug
$850.00
RG206847 PAK4 (tGFP-tagged) - Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2 10 ug
$750.00
SC301961 PAK4 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2 10 ug
$606.00

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