CEBP Beta (CEBPB) (NM_005194) Human Untagged Clone
$457.00
5 Days*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | CEBP Beta |
| Synonyms | C/EBP-beta; IL6DBP; NF-IL6; TCF5 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_005194 |
| Insert Size | 1038 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_005194.2, NP_005185.2 |
| RefSeq Size | 1837 bp |
| RefSeq ORF | 1038 bp |
| Locus ID | 1051 |
| UniProt ID | P17676 |
| Cytogenetics | 20q13.13 |
| Domains | BRLZ |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
| Summary | This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. provided by RefSeq, Oct 2013 Transcript Variant: This variant (1) encodes multiple isoforms through the use of alternative translation initiation codons. The isoform (a, also known as LAP*) represented in this RefSeq results from translation initiation at the 5' most AUG start codon and is the longest isoform. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_005194" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC205882 | CEBPB (Myc-DDK-tagged)-Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) | 10 ug |
$686.00
|
|
| RC205882L1 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB), Myc-DDK-tagged | 10 ug |
$986.00
|
|
| RC205882L2 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB), mGFP tagged | 10 ug |
$986.00
|
|
| RC205882L3 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB), Myc-DDK-tagged | 10 ug |
$986.00
|
|
| RC205882L4 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB), mGFP tagged | 10 ug |
$986.00
|
|
| RG205882 | CEBPB (tGFP-tagged) - Human CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) | 10 ug |
$886.00
|
|
Citations
CEBPB Expression in Tumor Cells Drives Immune Evasion in Colorectal Cancer via CTLA4 Up-regulation in T Cells
Yun, Park, Yun et al
Cancer Commun (Lond) (2026) 46, 0013 DOI: 10.34133/cancomm.0013
Yun, Park, Yun et al
Cancer Commun (Lond) (2026) 46, 0013 DOI: 10.34133/cancomm.0013
Cited by 1
AI Summary: OriGene’s human CEBPB (SC319561) and mouse Cebpb (MR227563) cDNA products were used as templates for PCR amplification to generate constructs for functional studies investigating the role of CEBPB in immune evasion in colorectal cancer.
Snippet: yes">LCN2 from HEK293T and mouse Lcn2 from CT26 were generated by PCR amplification, cDNA was obtained from human CEBPB (SC319561, OriGene) and mouse Cebpb (MR227563, OriGene), open reading frame clones were cloned into entry vector pDONR221 (12536017, Thermo Fisher Scientific), and entry vector with
Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder
Canchi, Swinton, Rissman et al
J Neuroinflammation (2020) 17 (1), 112 DOI: 10.1186/s12974-020-01781-w
Canchi, Swinton, Rissman et al
J Neuroinflammation (2020) 17 (1), 112 DOI: 10.1186/s12974-020-01781-w
Cited by 22
AI Summary: OriGene’s pC/EBPβ plasmid (CAT. SC319561) was used to transfect human astroglial cells, enabling the study of C/EBPβ’s role in gene expression changes associated with HIV-associated neurocognitive disorder.
Snippet: …SC319561) (1 μg) with p3000 were diluted separately in Opti-Mem Media and then mixed together at a 1:1 ratio and left to incubate for 15 min at room temp;- HIV-associated neurocognitive disorders (HAND) persist in the era of combined antiretroviral therapy (ART) despite reductions in viral load (VL) and overall disease severity. …
C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
Gardiner, Abegglen, Huang et al
Oncotarget (2017) 8 (16), 26013-26026 DOI: 10.18632/oncotarget.14847
Gardiner, Abegglen, Huang et al
Oncotarget (2017) 8 (16), 26013-26026 DOI: 10.18632/oncotarget.14847
Snippet: CEBPB was cloned from an Origene Human cDNA clone (SC319561, Origene;accession number NM_005194.2). …
Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions
Segura, Jubierre, Li et al
Oncotarget (2017) 8 (16), 26298-26311 DOI: 10.18632/oncotarget.15459
Segura, Jubierre, Li et al
Oncotarget (2017) 8 (16), 26298-26311 DOI: 10.18632/oncotarget.15459
Snippet: he vectors pCMV6-XL4-BACH1, pCMV6-XL5-PAX9, pCMV6-XL5-ZNF148, pCMV6-XL5-ZNF83, pCMV6-AC-CEBPB, and pCMV6-XL-ZEB1 were purchased from Origene (Rockville, MD, USA). For transactivation experiments, transfection efficiency (70–75%) was monitored by scoring GFP positive cells at 48 hours post-transfection
Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis
Chen, Tian, Li et al
Tumour Biol. (2015)
Chen, Tian, Li et al
Tumour Biol. (2015)
Cited by 17
AI Summary: OriGene contributed to this study by providing the C/EBPβ cDNA clone, which was used to investigate the role of C/EBPβ in regulating cell cycle arrest and apoptosis in hepatocellular carcinoma cells treated with the isocorydine derivative.
Snippet: Vector construction and lentivirus packaging The C/EBPβ complementary DNA (cDNA) clone was purchased from OriGene. The above cDNA sequences were cloned into the lentiviral expression vector pWPXL (Addgene) by replacement of the GFP frag- ment. ... Cite SaveSaving
Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p
He, Qi, Jia et al
Cancer Lett. (2015) 368 (1), 115-25 DOI: 10.1016/j.canlet.2015.07.036
He, Qi, Jia et al
Cancer Lett. (2015) 368 (1), 115-25 DOI: 10.1016/j.canlet.2015.07.036
Cited by 51
AI Summary: OriGene products pCMV6-AC-CEBPB and pCMV6-AC-POU2F1 plasmids were used to overexpress the transcription factors CEBPB and POU2F1, enabling the study of their roles in regulating miR-542-3p expression in the context of tumor-induced angiogenesis.
Snippet: corresponding pGL3-promoter plasmid. Cells were cotransfected with the pGL3-promoter plasmids along with pCMV6-AC-CEBPB or pCMV6-AC-POU2F1 plasmid (Origene) using Lipofectamine 2000. Cells were harvested ... Cite SaveSaving
Showing 1-6 of 12 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
