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Complement Component 6 (C6) (NM_001115131) Human Untagged Clone

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SKU
SC319008
C6 (untagged)-Human complement component 6 (C6), transcript variant 2
  $942.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol Complement Component 6
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC319008 representing NM_001115131.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGGCCAGACGCTCTGTCTTGTACTTCATCCTGCTGAATGCTCTGATCAACAAGGGCCAAGCCTGCTTC
TGTGATCACTATGCATGGACTCAGTGGACCAGCTGCTCAAAAACTTGCAATTCTGGAACCCAGAGCAGA
CACAGACAAATAGTAGTAGATAAGTACTACCAGGAAAACTTTTGTGAACAGATTTGCAGCAAGCAGGAG
ACTAGAGAATGTAACTGGCAAAGATGCCCCATCAACTGCCTCCTGGGAGATTTTGGACCATGGTCAGAC
TGTGACCCTTGTATTGAAAAACAGTCTAAAGTTAGATCTGTCTTGCGTCCCAGTCAGTTTGGGGGACAG
CCATGCACTGCGCCTCTGGTAGCCTTTCAACCATGCATTCCATCTAAGCTCTGCAAAATTGAAGAGGCT
GACTGCAAGAATAAATTTCGCTGTGACAGTGGCCGCTGCATTGCCAGAAAGTTAGAATGCAATGGAGAA
AATGACTGTGGAGACAATTCAGATGAAAGGGACTGTGGGAGGACAAAGGCAGTATGCACACGGAAGTAT
AATCCCATCCCTAGTGTACAGTTGATGGGCAATGGGTTTCATTTTCTGGCAGGAGAGCCCAGAGGAGAA
GTCCTTGATAACTCTTTCACTGGAGGAATATGTAAAACTGTCAAAAGCAGTAGGACAAGTAATCCATAC
CGTGTTCCGGCCAATCTGGAAAATGTCGGCTTTGAGGTACAAACTGCAGAAGATGACTTGAAAACAGAT
TTCTACAAGGATTTAACTTCTCTTGGACACAATGAAAATCAACAAGGCTCATTCTCAAGTCAGGGGGGG
AGCTCTTTCAGTGTACCAATTTTTTATTCCTCAAAGAGAAGTGAAAATATCAACCATAATTCTGCCTTC
AAACAAGCCATTCAAGCCTCTCACAAAAAGGATTCTAGTTTTATTAGGATCCATAAAGTGATGAAAGTC
TTAAACTTCACAACGAAAGCTAAAGATCTGCACCTTTCTGATGTCTTTTTGAAAGCACTTAACCATCTG
CCTCTAGAATACAACTCTGCTTTGTACAGCCGAATATTCGATGACTTTGGGACTCATTACTTCACCTCT
GGCTCCCTGGGAGGCGTGTATGACCTTCTCTATCAGTTTAGCAGTGAGGAACTAAAGAACTCAGGTTTA
ACCGAGGAAGAAGCCAAACACTGTGTCAGGATTGAAACAAAGAAACGCGTTTTATTTGCTAAGAAAACA
AAAGTGGAACATAGGTGCACCACCAACAAGCTGTCAGAGAAACATGAAGGTTCATTTATACAGGGAGCA
GAGAAATCCATATCCCTGATTCGAGGTGGAAGGAGTGAATATGGAGCAGCTTTGGCATGGGAGAAAGGG
AGCTCTGGTCTGGAGGAGAAGACATTTTCTGAGTGGTTAGAATCAGTGAAGGAAAATCCTGCTGTGATT
GACTTTGAGCTTGCCCCCATCGTGGACTTGGTAAGAAACATCCCCTGTGCAGTGACAAAACGGAACAAC
CTCAGGAAAGCTTTGCAAGAGTATGCAGCCAAGTTCGATCCTTGCCAGTGTGCTCCATGCCCTAATAAT
GGCCGACCCACCCTCTCAGGGACTGAATGTCTGTGTGTGTGTCAGAGTGGCACCTATGGTGAGAACTGT
GAGAAACAGTCTCCAGATTATAAATCCAATGCAGTAGACGGACAGTGGGGTTGTTGGTCTTCCTGGAGT
ACCTGTGATGCTACTTATAAGAGATCGAGAACCCGAGAATGCAATAATCCTGCCCCCCAACGAGGAGGG
AAACGCTGTGAGGGGGAGAAGCGACAAGAGGAAGACTGCACATTTTCAATCATGGAAAACAATGGACAA
CCATGTATCAATGATGACGAAGAAATGAAAGAGGTCGATCTTCCTGAGATAGAAGCAGATTCCGGGTGT
CCTCAGCCAGTTCCTCCAGAAAATGGATTTATCCGGAATGAAAAGCAACTATACTTGGTTGGAGAAGAT
GTTGAAATTTCATGCCTTACTGGCTTTGAAACTGTTGGATACCAGTACTTCAGATGCTTACCAGACGGG
ACCTGGAGACAAGGGGATGTGGAATGCCAACGGACGGAGTGCATCAAGCCAGTTGTGCAGGAAGTCCTG
ACAATTACACCATTTCAGAGATTGTATAGAATTGGTGAATCCATTGAGCTAACTTGCCCCAAAGGCTTT
GTTGTTGCTGGGCCATCAAGGTACACATGCCAGGGGAATTCCTGGACACCACCCATTTCAAACTCTCTC
ACCTGTGAAAAAGATACTCTAACAAAATTAAAAGGCCATTGTCAGCTGGGACAGAAACAATCAGGATCT
GAATGCATTTGTATGTCTCCAGAAGAAGACTGTAGCCATCATTCAGAAGATCTCTGTGTGTTTGACACA
GACTCCAACGATTACTTTACTTCACCCGCTTGTAAGTTTTTGGCTGAGAAATGTTTAAATAATCAGCAA
CTCCATTTTCTACATATTGGTTCCTGCCAAGACGGCCGCCAGTTAGAATGGGGTCTTGAAAGGACAAGA
CTTTCATCCAACAGCACAAAGAAAGAATCCTGTGGCTATGACACCTGCTATGACTGGGAAAAATGTTCA
GCCTCCACTTCCAAATGTGTCTGCCTATTGCCCCCACAGTGCTTCAAGGGTGGAAACCAACTCTACTGT
GTCAAAATGGGATCATCAACAAGTGAGAAAACATTGAACATCTGTGAAGTGGGAACTATAAGATGTGCA
AACAGGAAGATGGAAATACTGCATCCTGGAAAGTGTTTGGCCTAG
AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGAT
ATCCTGGATTACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-RsrII |
ACCN NM_001115131
Insert Size 2805 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001115131.2
RefSeq Size 3749 bp
RefSeq ORF 2805 bp
Locus ID 729
UniProt ID P13671
Cytogenetics 5p13.1
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
MW 104.8 kDa
Summary This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.provided by RefSeq, Nov 2012
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_001115131" in other vectors (4)
SKU Description Size Price
RC226266 C6 (Myc-DDK-tagged)-Human complement component 6 (C6), transcript variant 2 10 ug
$855.00
RC226266L3 Lenti ORF clone of Human complement component 6 (C6), transcript variant 2, Myc-DDK-tagged 10 ug
$1,155.00
RC226266L4 Lenti ORF clone of Human complement component 6 (C6), transcript variant 2, mGFP tagged 10 ug
$1,155.00
RG226266 C6 (tGFP-tagged) - Human complement component 6 (C6), transcript variant 2 10 ug
$1,055.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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