PROX1 (NM_002763) Human Untagged Clone
$1,013.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PROX1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_002763 |
| Insert Size | 5500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002763.3, NP_002754.2 |
| RefSeq Size | 3088 bp |
| RefSeq ORF | 2214 bp |
| Locus ID | 5629 |
| UniProt ID | Q92786 |
| Cytogenetics | 1q32.3 |
| Domains | Prox1 |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS |
| Summary | The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2012 Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_002763" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC201140 | PROX1 (Myc-DDK-tagged)-Human prospero homeobox 1 (PROX1) | 10 ug |
$1,013.00
|
|
| RC201140L1 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), Myc-DDK-tagged | 10 ug |
$1,313.00
|
|
| RC201140L2 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), mGFP tagged | 10 ug |
$1,313.00
|
|
| RC201140L3 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), Myc-DDK-tagged | 10 ug |
$1,313.00
|
|
| RC201140L4 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), mGFP tagged | 10 ug |
$1,313.00
|
|
| RG201140 | PROX1 (tGFP-tagged) - Human prospero homeobox 1 (PROX1) | 10 ug |
$1,213.00
|
|
Citations
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1
Flister, Wilber, Hall et al
Blood (2010) 115 (2), 418-29 DOI: 10.1182/blood-2008-12-196840
Flister, Wilber, Hall et al
Blood (2010) 115 (2), 418-29 DOI: 10.1182/blood-2008-12-196840
Cited by 214
Showing 1-1 of 1 papers.
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