RIP3 (RIPK3) (NM_006871) Human Untagged Clone
$725.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | RIP3 |
| Synonyms | RIP3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_006871 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_006871.2, NP_006862.2 |
| RefSeq Size | 1940 bp |
| RefSeq ORF | 1557 bp |
| Locus ID | 11035 |
| UniProt ID | Q9Y572 |
| Cytogenetics | 14q12 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Cytosolic DNA-sensing pathway |
| Summary | The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_006871" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC209549 | RIPK3 (Myc-DDK-tagged)-Human receptor-interacting serine-threonine kinase 3 (RIPK3) | 10 ug |
$723.00
|
|
| RC209549L1 | Lenti ORF clone of Human receptor-interacting serine-threonine kinase 3 (RIPK3), Myc-DDK-tagged | 10 ug |
$1,023.00
|
|
| RC209549L2 | Lenti ORF clone of Human receptor-interacting serine-threonine kinase 3 (RIPK3), mGFP tagged | 10 ug |
$1,023.00
|
|
| RC209549L3 | Lenti ORF clone of Human receptor-interacting serine-threonine kinase 3 (RIPK3), Myc-DDK-tagged | 10 ug |
$1,023.00
|
|
| RC209549L4 | Lenti ORF clone of Human receptor-interacting serine-threonine kinase 3 (RIPK3), mGFP tagged | 10 ug |
$1,023.00
|
|
| RG209549 | RIPK3 (tGFP-tagged) - Human receptor-interacting serine-threonine kinase 3 (RIPK3) | 10 ug |
$923.00
|
|
Citations
Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease
Saeed, Jun, Jang et al
World J. Gastroenterol. (2018) 24 (48), 5477-5490 DOI: 10.3748/wjg.v24.i48.5477
Saeed, Jun, Jang et al
World J. Gastroenterol. (2018) 24 (48), 5477-5490 DOI: 10.3748/wjg.v24.i48.5477
AI Summary: OriGene's TrueORF cDNA Clones were used to amplify human RIP3 coding regions, enabling the construction of RIP3 non-viral expression vectors for functional studies in this paper.
Snippet: Germany). RIP3 non-viral vector construction. The human RIP3 (NM_006871) coding regions were amplified by polymerase chain reaction (PCR) using TrueORF cDNA Clones (Origene, Rockville, MD, United States) for genes
Showing 1-1 of 1 papers.
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