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SLIT1 (NM_003061) Human Untagged Clone

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SKU
SC303271
SLIT1 (untagged)-Human slit homolog 1 (Drosophila) (SLIT1)
  $1,444.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SLIT1
Synonyms MEGF4; SLIL1; SLIT-1; SLIT3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC303271 representing NM_003061.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGGCGCTGACTCCCGGGTGGGGGTCCTCGGCGGGGCCGGTCCGGCCGGAGCTCTGGCTGCTGCTGTGG
GCAGCCGCGTGGCGCCTGGGTGCCTCGGCGTGCCCCGCCCTCTGCACCTGCACCGGAACCACGGTGGAC
TGCCACGGCACGGGGCTGCAGGCCATTCCCAAGAATATACCTCGGAACACCGAGCGCCTGGAACTCAAT
GGCAACAACATCACTCGGATCCATAAGAATGACTTTGCGGGGCTCAAGCAGCTGCGGGTGCTGCAGCTG
ATGGAGAACCAGATTGGAGCAGTGGAACGTGGTGCTTTTGATGACATGAAGGAGCTGGAGCGGCTGCGA
CTGAACCGAAACCAGCTGCACATGTTACCGGAACTGCTGTTCCAGAACAACCAGGCTTTGTCAAGACTG
GACTTGAGTGAGAACGCCATCCAGGCCATCCCCAGGAAAGCTTTTCGGGGAGCTACGGACCTTAAAAAT
TTACAGCTGGACAAGAACCAGATCAGCTGCATTGAGGAAGGGGCCTTCCGTGCTCTGCGGGGGCTGGAG
GTGCTGACCCTGAACAACAACAATATCACCACCATCCCCGTGTCCAGCTTCAACCATATGCCCAAGCTA
CGGACCTTCCGCCTGCACTCCAACCACCTGTTTTGCGACTGCCACCTGGCCTGGCTCTCGCAGTGGCTG
AGGCAGCGGCCAACCATCGGGCTCTTCACCCAGTGCTCGGGCCCAGCCAGCCTGCGTGGCCTCAATGTG
GCAGAGGTCCAGAAGAGTGAGTTCAGCTGCTCAGGCCAGGGAGAAGCGGGGCGCGTGCCCACCTGCACC
CTGTCCTCCGGCTCCTGCCCGGCCATGTGCACCTGCAGCAATGGCATCGTGGACTGTCGTGGAAAAGGC
CTCACTGCCATCCCGGCCAACCTGCCCGAGACCATGACGGAGATACGCCTGGAGCTGAACGGCATCAAG
TCCATCCCTCCTGGAGCCTTCTCACCCTACAGAAAGCTACGGAGGATAGACCTGAGCAACAATCAGATC
GCTGAGATTGCACCCGACGCCTTCCAGGGCCTCCGCTCCCTGAACTCGCTGGTCCTCTATGGAAACAAG
ATCACAGACCTCCCCCGTGGTGTGTTTGGAGGCCTATACACCCTACAGCTCCTGCTCCTGAATGCCAAC
AAGATCAACTGCATCCGGCCCGATGCCTTCCAGGACCTGCAGAACCTCTCACTGCTCTCCCTGTATGAC
AACAAGATCCAGAGCCTCGCCAAGGGCACTTTCACCTCCCTGCGGGCCATCCAGACTCTGCACCTGGCG
CAGAACCCTTTCATTTGCGACTGTAACCTCAAGTGGCTGGCAGACTTCCTGCGCACCAATCCCATCGAG
ACGAGTGGTGCCCGCTGTGCCAGTCCCCGGCGCCTCGCCAACAAGCGCATCGGGCAGATCAAGAGCAAG
AAGTTCCGGTGCTCAGCCAAAGAGCAGTACTTCATTCCAGGCACGGAGGATTACCAGCTGAACAGCGAG
TGCAACAGCGACGTGGTCTGTCCCCACAAGTGCCGCTGTGAGGCCAACGTGGTGGAGTGCTCCAGCCTG
AAGCTCACCAAGATCCCTGAGCGCATCCCCCAGTCCACGGCAGAACTGCGATTGAATAACAATGAGATT
TCCATCCTGGAGGCCACTGGGATGTTTAAAAAACTTACACATCTGAAGAAAATCAATCTGAGCAACAAC
AAGGTGTCAGAAATTGAAGATGGGGCCTTCGAGGGCGCAGCCTCTGTGAGCGAGCTGCACCTAACTGCC
AACCAGCTGGAGTCCATCCGGAGCGGCATGTTCCGGGGTCTGGATGGCTTGAGGACCCTAATGCTGCGG
AACAACCGCATCAGCTGCATCCACAACGACAGCTTCACGGGCCTGCGCAACGTCCGGCTCCTCTCGCTC
TACGACAACCAGATCACCACCGTATCCCCAGGAGCCTTCGACACCCTCCAGTCCCTCTCCACACTGAAT
CTCCTGGCCAACCCTTTCAACTGCAACTGCCAGCTGGCCTGGCTAGGAGGCTGGCTACGGAAGCGCAAG
ATCGTGACGGGGAACCCGCGATGCCAGAACCCTGACTTTTTGCGGCAGATTCCCCTGCAGGACGTGGCC
TTCCCTGACTTCAGGTGTGAGGAAGGCCAGGAGGAGGGGGGCTGCCTGCCCCGCCCACAGTGCCCACAG
GAGTGCGCCTGCCTGGACACCGTGGTCCGATGCAGCAACAAGCACCTGCGGGCCCTGCCCAAGGGCATT
CCCAAGAATGTCACAGAACTCTATTTGGACGGGAACCAGTTCACGCTGGTTCCGGGACAGCTGTCTACC
TTCAAGTACCTGCAGCTCGTGGACCTGAGCAACAACAAGATCAGTTCCTTAAGCAATTCCTCCTTCACC
AACATGAGCCAGCTGACCACTCTGATCCTCAGCTACAATGCCCTGCAGTGCATCCCGCCTTTGGCCTTC
CAGGGACTCCGCTCCCTGCGCCTGCTGTCTCTCCACGGCAATGACATCTCCACCCTCCAAGAGGGCATC
TTTGCAGACGTGACCTCCCTGTCTCACCTGGCCATTGGTGCCAACCCCCTATACTGTGACTGCCACCTC
CGCTGGCTGTCCAGCTGGGTGAAGACTGGCTACAAGGAACCGGGCATTGCTCGTTGTGCTGGGCCCCAG
GACATGGAGGGCAAGCTGCTCCTCACCACGCCTGCCAAGAAGTTTGAATGCCAAGGTCCTCCAACGCTG
GCTGTCCAGGCCAAGTGTGATCTCTGCTTGTCCAGTCCGTGCCAGAACCAGGGCACCTGCCACAACGAC
CCCCTTGAGGTGTACAGGTGCGCCTGCCCCAGCGGCTATAAGGGTCGAGACTGTGAGGTGTCCCTGGAC
AGCTGTTCCAGTGGCCCCTGTGAAAATGGGGGCACCTGCCATGCACAGGAGGGCGAGGATGCCCCGTTC
ACGTGCTCCTGTCCCACCGGCTTTGAAGGACCAACCTGTGGGGTGAACACAGATGACTGTGTGGATCAT
GCCTGTGCCAATGGGGGCGTCTGTGTGGATGGTGTGGGCAACTACACCTGCCAGTGCCCCCTGCAGTAT
GAGGGAAAGGCCTGTGAGCAGCTGGTGGACTTGTGCTCTCCGGATCTGAACCCATGTCAACACGAGGCC
CAGTGTGTGGGCACCCCGGATGGGCCCAGGTGTGAGTGCATGCCAGGTTATGCAGGTGACAACTGCAGT
GAGAACCAGGATGACTGCAGGGACCACCGCTGCCAGAATGGGGCCCAGTGTATGGATGAAGTCAACAGC
TACTCCTGCCTCTGTGCTGAGGGCTACAGTGGACAGCTCTGTGAGATCCCTCCCCATCTGCCTGCCCCC
AAGAGCCCCTGTGAGGGGACTGAGTGCCAGAATGGGGCCAACTGTGTGGACCAGGGCAACAGGCCTGTG
TGCCAGTGCCTCCCAGGCTTCGGTGGCCCTGAGTGTGAGAAGTTGCTCAGTGTCAACTTTGTGGATCGG
GACACTTACCTGCAGTTCACTGACCTGCAAAACTGGCCACGGGCCAACATCACGTTGCAGGTCTCCACG
GCAGAGGACAATGGGATCCTTCTGTACAACGGGGACAACGACCACATTGCAGTTGAGCTGTACCAGGGC
CATGTGCGTGTCAGCTACGACCCAGGCAGCTACCCCAGCTCTGCCATCTACAGTGCTGAGACGATCAAC
GATGGGCAATTCCACACCGTTGAGCTGGTTGCCTTTGACCAGATGGTGAATCTCTCCATTGATGGCGGG
AGCCCCATGACCATGGACAACTTTGGCAAACATTACACGCTCAACAGCGAGGCGCCACTCTATGTGGGA
GGGATGCCCGTGGATGTCAACTCAGCTGCCTTCCGCCTGTGGCAGATCCTCAACGGCACCGGCTTCCAC
GGTTGCATCCGAAACCTGTACATCAACAACGAGCTGCAGGACTTCACCAAGACGCAGATGAAGCCAGGC
GTGGTGCCAGGCTGCGAACCCTGCCGCAAGCTCTACTGCCTGCATGGCATCTGCCAGCCCAATGCCACC
CCAGGGCCCATGTGCCACTGCGAGGCTGGCTGGGTGGGCCTGCACTGTGACCAGCCCGCTGACGGCCCC
TGCCATGGCCACAAGTGTGTCCATGGGCAATGCGTGCCCCTCGACGCTCTTTCCTACAGCTGCCAGTGC
CAGGATGGGTACTCGGGGGCACTGTGCAACCAGGCCGGGGCCCTGGCAGAGCCCTGCAGAGGCCTGCAG
TGCCTGCATGGCCACTGCCAGGCCTCAGGCACCAAGGGGGCACACTGTGTGTGTGACCCCGGCTTTTCG
GGCGAGCTGTGTGAGCAAGAGTCCGAGTGCCGGGGGGACCCTGTCCGGGACTTTCACCAGGTCCAGAGG
GGCTATGCCATCTGCCAGACCACGCGCCCCCTGTCATGGGTGGAGTGCCGGGGCTCGTGCCCAGGCCAG
GGCTGCTGCCAGGGCCTTCGGCTGAAGCGGAGGAAGTTCACCTTTGAGTGCAGCGATGGGACCTCTTTT
GCCGAGGAGGTGGAAAAGCCCACCAAGTGTGGCTGTGCCCTCTGCGCATAG
ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites SgfI-MluI |
ACCN NM_003061
Insert Size 4605 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_003061.2
RefSeq Size 7949 bp
RefSeq ORF 4605 bp
Locus ID 6585
UniProt ID O75093
Cytogenetics 10q24.1
Protein Families Druggable Genome
Protein Pathways Axon guidance
MW 167.9 kDa
Summary Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_003061" in other vectors (6)
SKU Description Size Price
RC218562 SLIT1 (Myc-DDK-tagged)-Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$589.00 $1,312.00
RC218562L1 Lenti-ORF clone of SLIT1 (Myc-DDK-tagged)-Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$1,612.00
RC218562L2 Lenti-ORF clone of SLIT1 (mGFP-tagged)-Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$1,612.00
RC218562L3 Lenti-ORF clone of SLIT1 (Myc-DDK-tagged)-Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$1,612.00
RC218562L4 Lenti-ORF clone of SLIT1 (mGFP-tagged)-Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$1,612.00
RG218562 SLIT1 (tGFP-tagged) - Human slit homolog 1 (Drosophila) (SLIT1) 10 ug
$1,512.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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