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EXD2 (NM_018199) Human Untagged Clone

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SKU
SC128176
EXD2 (untagged)-Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol EXD2
Synonyms C14orf114; EXDL2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC128176 sequence for NM_018199 edited (data generated by NextGen Sequencing)
ATGGCCTCCCCAAGTGGCCTGTGTGTCTTGGTTCGCCTGCCCAAGCTAATCTGTGGAGGA
AAAACACTACCAAGAACGTTATTGGATATTTTGGCAGATGGCACCATTTTGAAAGTTGGA
GTGGGATGCTCAGAAGATGCCAGCAAGCTTCTGCAGGATTATGGCCTCGTTGTTAGGGGG
TGCCTGGACCTCCGATACCTAGCCATGCGGCAGAGAAACAATTTGCTCTGTAATGGGCTT
AGCCTGAAGTCCCTCGCTGAGACTGTTTTGAACTTTCCCCTTGACAAGTCCCTTCTACTT
CGTTGCAGCAACTGGGATGCTGAGACTCTCACAGAGGACCAGGTAATTTATGCTGCCAGG
GATGCCCAGATTTCAGTGGCTCTCTTTCTTCATCTTCTTGGATACCCTTTCTCTAGGAAT
TCACCTGGAGAAAAAAACGATGACCACAGTAGCTGGAGAAAAGTCTTGGAAAAATGCCAG
GGTGTGGTCGACATCCCATTTCGAAGCAAAGGAATGAGCAGATTGGGAGAAGAGGTTAAT
GGGGAAGCAACAGAATCTCAGCAGAAGCCAAGAAATAAGAAGTCTAAGATGGATGGGATG
GTGCCAGGCAACCACCAAGGGAGAGACCCCAGAAAACATAAAAGAAAGCCTCTGGGGGTG
GGCTATTCTGCCAGAAAATCACCTCTTTATGATAACTGCTTTCTCCATGCTCCTGATGGA
CAGCCCCTCTGCACTTGTGATAGAAGAAAAGCTCAGTGGTACCTGGACAAAGGCATTGGT
GAGCTGGTGAGTGAAGAGCCCTTTGTGGTGAAGCTACGGTTTGAACCTGCAGGAAGGCCC
GAATCTCCTGGAGACTATTACTTGATGGTTAAAGAGAACCTGTGTGTAGTGTGTGGCAAG
AGAGACTCCTACATTCGGAAGAACGTGATTCCACATGAGTACCGGAAGCACTTCCCCATC
GAGATGAAGGACCACAACTCCCACGATGTGCTGCTGCTCTGCACCTCCTGCCATGCCATT
TCCAACTACTATGACAACCATCTGAAGCAGCAGCTGGCCAAGGAGTTCCAGGCCCCCATC
GGCTCTGAGGAGGGCTTGCGCCTGCTGGAAGATCCTGAGCGCCGGCAGGTGCGTTCTGGG
GCCAGGGCCCTGCTCAACGCGGAGAGCCTGCCTACTCAGCGAAAGGAGGAGCTGCTGCAA
GCACTCAGAGAGTTTTATAACACAGACGTGGTCACAGAGGAGATGCTTCAAGAGGCTGCC
AGCCTGGAGACCAGAATCTCCAATGAAAACTATGTTCCTCACGGGCTGAAGGTGGTGCAG
TGTCACAGCCAGGGTGGCCTGCGCTCCCTCATGCAGCTGGAGAGCCGCTGGCGTCAGCAC
TTCCTGGACTCCATGCAGCCCAAGCACCTGCCCCAGCAGTGGTCAGTGGACCACAACCAT
CAGAAGCTGCTCCGGAAATTCGGGGAAGATCTTCCCATCCAGCTGTCTTGA

Clone variation with respect to NM_018199.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_018199 unedited
ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGA
GGATCAAATCGAGCCCTTGCTTAGAAGTGAATTAGAAGATTTTCCAGTACTTGGAATTGA
CTGTGAGTGGGTAAATTTGGAAGGCAAAGCCAGCCCTCTGTCACTTCTACAAATGGCCTC
CCCAAGTGGCCTGTGTGTCTTGGTTCGCCTGCCCAAGCTAATCTGTGGAGGAAAAACACT
ACCAAGAACGTTATTGGATATTTTGGCAGATGGCACCATTTTGAAAGTTGGAGTGGGATG
CTCAGAAGATGCCAGCAAGCTTCTGCAGGATTATGGCCTCGTTGTTAGGGGGTGCCTGGA
CCTCCGATACCTAGCCATGCGGCAGAGAAACAATTTGCTCTGTAATGGGCTTAGCCTGAA
GTCCCTCGCTGAGACTGTTTTGAACTTTCCCCTTGACAAGTCCCTTCTACTTCGTTGCAG
CAACTGGGATGCTGAGACTCTCACAGAGGACCAGGTAATTTATGCTGCCAGGGATGCCCA
GATTTCAGTGGCTCTCTTTCTTCATCTTCTTGGATACCCTTTCTCTAGGAATTCACCTGG
AGAAAAAAACGATGACCACAGTAGCTGGAGAAAAGTCTTGGAAAAATGCCANGGTGTGGT
CGACATCCCATTTCGAAGCNAGGAATGAGCAGATTGGGAGAAAGAGGTTAATGGGGAAGA
ACAGAATCTCAGCAGAAGCCAGAAATAAGAGTCTAGATGGATGGGATGGTGCCCAGGCAC
CACCAGGGAGAGACCCAGAAACTAAAGAAGCTCTGGGGGGTGGGCTATCTGCAAAAATAC
CTCTTAGATACTGCTTCTTCTGCTCTGAGGGAAGCCCTTGGACTGTGAAGAGAAACTTAN
TGTACTGACAGGCATGTGANCTGGAGGAAACCCTTTGGAAACACCGTTACCCTCGGAGGC
CATTT
3' Read Nucleotide Sequence
>OriGene 3' genomic read for NM_018199 unedited
CGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTGAAATTTAAAATTTTATTTTT
TTACCTTTTTTTTACATTTTTATTTTAAAATAAACAGTGTTTCCAAAAAACATTGACTAC
AAGGGGGAAATGAGGCAATAAGGTTGGAAGAAGGGAAGGACTCAAGAAGAAATGCTGAAC
CTGCAAACACAATGATCAGGGAGCATGCAGAGAGGCCCTTGCTGTGACACTGTCCTCTCA
CTGCTACTCCTATGAAGCCCAGTGACTATGCTGGGACACTGGAGCTAAAGGGTCAAAGAG
AAGCATTTCATTCCTAAAAGGTGATGTCAATTTGTACTTAGCCCCAGCAATGTGAATCCC
CCTCTTCACAGTCCAATTCTAAGATTCCATTCTTAAGAAATTACCAAAGATAGAGCCAAA
GAGATATATACAAGAAACTTTATCACATCATCATTGATAATAAAAGTATCTGAAACAACC
AAAATTTTCAACAGTGTGGGGATGGATAAGGTAGAACCACTAGAAATCTATTTTCAAAGA
TTTAAAAACATAGGAAGTTACTCGTGATACCATGTTAATCAGTGAGAGGGTAAAGTTAGG
ATACCAACCTGTATCTATGTATGACCTTCAATTTTGTGTAAATATACACCTTATATGCAC
TTTTTAATACTGAAAGGAAATTCATAAACATATCAGCAAAGTTTAGCTCTGTTTTAGATG
GAGAGAAGATGGCTAATTTTTATTCTTTGNTTAGATTCTTCTGTAATGAGCATTGTTACT
TTTATATCAGAAAAATAGACATTTGCCATANNATAAGTCTACCCTCAATCTCTGATTTAG
ACGACATTTGTAGTCTTTAGAAAAGCTGCNTAAGTCAAGCAGACTCAAGAAAAAGATTCA
ATCTAACAGTGACTCTCCCTGAAAAGATGAGAAATCTGTGTGACGCANCTGGCTTTTCCT
CTACTTGCTGNGGCTTT
Restriction Sites NotI-NotI |
ACCN NM_018199
Insert Size 4250 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_018199.1, NP_060669.1
RefSeq Size 2833 bp
RefSeq ORF 1491 bp
Locus ID 55218
UniProt ID Q9NVH0
Cytogenetics 14q24.1
Domains 3_5_exonuclease
Summary Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (5) is missing 2 internal exons compared to variant 1. This results in translation initiation from an in-frame downstream AUG and a shorter isoform (2) compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_018199" in other vectors (6)
SKU Description Size Price
RC200127 EXD2 (Myc-DDK-tagged)-Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5 10 ug
$457.00
RC200127L1 Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, Myc-DDK-tagged 10 ug
$757.00
RC200127L2 Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, mGFP tagged 10 ug
$757.00
RC200127L3 Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, Myc-DDK-tagged 10 ug
$757.00
RC200127L4 Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, mGFP tagged 10 ug
$757.00
RG200127 EXD2 (tGFP-tagged) - Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5 10 ug
$489.00 $657.00

file-alt Citations

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