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CLK2 (NM_003993) Human Untagged Clone

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SKU
SC128171
CLK2 (untagged)-Human CDC-like kinase 2 (CLK2)
  $457.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CLK2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_003993 edited
AGCATTTCGTCGCCGCGGGGGTGCCGGGACTCCGGCCGCAGTGTCGCCGCCATCACGGAC
TTCCTGTGGGACAAGCGCACGGGCCTCGCCGCCAGAACGATGCCGCATCCTCGAAGGTAC
CACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCAT
AAGCGACGAAGAAGTCGCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGA
GAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTTCGTCCGACCGGAGG
GTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGA
GATGCCTACTATGACACAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGT
TACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGAGGCGCAGCCGGACA
TTTAGCCGCTCATCTTCGCAGCACAGCAGCCGGAGAGCCAAGAGTGTAGAGGACGACGCT
GAGGGCCACCTCATCTACCACGTCGGGGACTGGCTACAAGAGCGATATGAAATCGTTAGC
ACCTTAGGAGAGGGGACCTTCGGCCGAGTTGTACAATGTGTTGACCATCGCAGGGGTGGG
GCTCGAGTTGCCCTGAAGATCATTAAGAATGTGGAGAAGTACAAGGAAGCAGCTCGACTT
GAGATCAACGTGCTAGAGAAAATCAATGAGAAAGACCCTGACAACAAGAACCTCTGTGTC
CAGATGTTTGACTGGTTTGACTACCATGGCCACATGTGTATCTCCTTTGAGCTTCTGGGC
CTTAGCACCTTCGATTTCCTCAAAGACAACAACTACCTGCCCTACCCCATCCACCAAGTG
CGCCACATGGCCTTCCAGCTGTGCCAGGCTGTCAAGTTCCTCCATGATAACAAGCTGACA
CATACAGACCTCAAGCCTGAAAATATTCTGTTTGTGAATTCAGACTATGAGCTCACCTAC
AACCTAGAGAAGAAGCGAGATGAGCGCAGTGTGAAGAGCACAGCTGTGCGGGTGGTAGAC
TTTGGCAGTGCCACCTTTGACCATGAGCACCATAGCACCATTGTCTCCACTCGCCATTAC
CGAGCACCAGAAGTCATCCTTGAGTTGGGCTGGTCACAGCCTTGTGATGTGTGGAGTATA
GGCTGCATCATCTTTGAATACTATGTGGGATTCACCCTCTTCCAGACCCATGACAACAGA
GAGCATCTAGCCATGATGGAAAGGATCTTGGGTCCTATCCCTTCCCGGATGATCCGAAAG
ACAAGAAAGCAGAAATATTTTTACCGGGGTCGCCTGGATTGGGATGAGAACACATCAGCT
GGGCGCTATGTTCGTGAGAACTGCAAACCGCTGCGGCGGTATCTGACCTCAGAGGCAGAG
GAACACCACCAGCTCTTCGATCTGATTGAAAGCATGCTAGAGTATGAACCAGCTAAGCGG
CTGACCTTGGGTGAAGCCCTTCAGCATCCTTTCTTCGCCCGCCTTCGGGCTGAGCCGCCC
AACAAGTTGTGGGACTCCAGTCGGGATATCAGTCGGTGACGATCAGGCCCTGGGCCCCCC
TGCATCTTTTATAGCAGTGGGTGTCCAGTCCAGGACACTGGTGCTTTTTTATACAAGAGA
ACGAGCCAGAGTTCACTCC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_003993 unedited
ATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGGCGGAGCGGAGAGGCCAGAGC
CGGAGACCGAGCTGGGATCGGGCCCCGGGCGGGGGCGGTGCGAGCGGCGCCAAGCAGATC
TTAGGGGCGGGGACGGAGCCGGGGCGGGCGGGACTGAAGCGGAGCCCGGGAACGGGGCGG
GAGGTCCCAGGGTCCCGGGTTGGGGGGGGTGGAGCAGCATTTCGTCGCCGCGGGGGTGCC
GGGACTCCGGCCGCAGTGTCGCCGCCATCACGGACTTCCTGTGGGACAAGCGCACGGGCC
TCGCCGCCAGAACGATGCCGCATCCTCGAAGGTACCACTCCTCAGAGCGAGGCANGCCGG
GGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTCGCTCCTGG
TCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCT
GNAAGCAGTTATGATTGATCGTTCGTCCGCCGGGGAGGGTGTATGACCGGCGATACTGTG
GCAGNCTACAGACGCACGATATAGCCGGGGATCGGGGAGATGCCTACTATGACACAGACT
ATCGGCATTCCTATGAATTTCAGGGGGGGAACAGGAAGTTCCGGAACCAGGGCAAAACCG
GGGGGGACCCCAAAGGGGGAGGGGGGCACCCGGAATTTTACCTTTTTTTTTCCACCAAAA
CCGGGGACCAAGGTTTAAAGGGCACCTTTGGGCCCCTTTTTCCCCGGGGGGGGCGGTTTC
CAGAGGATTTAAAACTGCCCCTTTTGGAAGGGGGTCTTCCCGGTGTTCAATGGTGGCCCC
CGGGGGGGGGGGGGGCNNCCCCCCAAAAAAAAAAAGGGGGGAAAACACACGCACCC
Restriction Sites NotI-NotI |
ACCN NM_003993
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_003993.2, NP_003984.2
RefSeq Size 2175 bp
RefSeq ORF 1497 bp
Locus ID 1196
UniProt ID P49760
Cytogenetics 1q22
Domains pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase
Summary This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2014
Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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Documents
Resources
"NM_003993" in other vectors (7)
SKU Description Size Price
RC208778 CLK2 (Myc-DDK-tagged)-Human CDC-like kinase 2 (CLK2) 10 ug
$457.00
RC208778L1 Lenti ORF clone of Human CDC-like kinase 2 (CLK2), Myc-DDK-tagged 10 ug
$757.00
RC208778L2 Lenti ORF clone of Human CDC-like kinase 2 (CLK2), mGFP tagged 10 ug
$757.00
RC208778L3 Lenti ORF clone of Human CDC-like kinase 2 (CLK2), Myc-DDK-tagged 10 ug
$757.00
RC208778L4 Lenti ORF clone of Human CDC-like kinase 2 (CLK2), mGFP tagged 10 ug
$757.00
RG208778 CLK2 (tGFP-tagged) - Human CDC-like kinase 2 (CLK2) 10 ug
$489.00 $657.00
SC323449 CLK2 (untagged)-Kinase deficient mutant (K192M) of Human CDC-like kinase 2 (CLK2) 10 ug
$457.00

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