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CTDSP2 (NM_005730) Human Untagged Clone

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SKU
SC128037
CTDSP2 (untagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2)
  $300.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CTDSP2
Synonyms OS4; PSR2; SCP2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC128037 sequence for NM_005730 edited (data generated by NextGen Sequencing)
ATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAG
CAAGGCCTGGTCTCCAAGTCCTCTCCTAAGAAGCCTCGTGGACGTAACATCTTCAAGGCC
CTTTTCTGCTGTTTTCGCGCCCAGCATGTTGGCCAGTCAAGTTCCTCCACTGAGCTCGCT
GCGTATAAGGAGGAAGCAAACACCATTGCTAAGTCGGATCTGCTCCAGTGTCTCCAGTAC
CAGTTCTACCAGATCCCAGGGACCTGCCTGCTCCCAGAGGTGACAGAGGAAGATCAAGGA
AGGATCTGTGTGGTCATTGACCTCGATGAAACCCTTGTGCATAGCTCCTTTAAGCCAATC
AACAATGCTGACTTCATAGTGCCTATAGAGATTGAGGGGACCACTCACCAGGTGTATGTG
CTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATGTGTT
CTCTTCACTGCCAGCCTGGCCAAGTATGCCGACCCTGTGACAGACCTGCTGGACCGGTGT
GGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCTACGTC
AAGGACCTCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTCGCCT
GCTTCTTACATATTCCACCCCGAGAATGCAGTGCCTGTGCAGTCCTGGTTTGATGACATG
GCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAGAGGAC
GTCTACACCAGCCTTGGGCAGCTGCGGGCCCCTTAG

Clone variation with respect to NM_005730.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_005730 unedited
AGGCGGCCCGCGAATTCGCACGAGGGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGG
GGGCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCCTTTGTACAGGCCGCCTCCCTTCC
CGGTCCGGGGAGGAAACGAGAGGGGGGATGTGAACAGCTGTGGAAGTCGGAGTCTCGGGA
GCCGGAGCGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCC
TCCCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGATGGAACACGGCTCCATCATCACC
CAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAGCAAGGCCTGGTCTCCAAGTCCTCT
CCTAAGAAGCCTCGTGGACGTAACATCTTCAAGGCCCTTTTCTGCTGTTTTCGCGCCCAG
CATGTTGGCCAGTCAAGTTCCTCCACTGAGCTCGCTGCGTATAAGGAGGAAGCAAACACC
ATTGCTAAGTCGGATCTGCTCCAGTGTCTCCAGTACCAGTTCTACCAGATCCCAGGGACC
TGCCTGCTCCCAGAGGTGACAGAGGAAGATCAAGAAGGATCTGTGTGGTCATTGACCTCG
ATGAAACCCTTGTGCATAGCTCCTTTAAGCCAATCAACAATGCTGACTTCATAGTGCCTA
TAGAGATTGAGGGGACCACTCACCAGGNTGTATGTGCTCAANGAGCCTTTATGTGGATGA
GCTCCTGAGACGCATGGNGGAACTCTTTGNATGTGTTCTGCTCACTGGCAGCCTGGCCAA
GTATGCCGACCCTGTGACAGACTGCTGAACCGTGTGGGGGGGGTTCCGGCCCGCCTATTC
GTGAGTTTTTTGGGTGTTCACCAAGGCTGGTCGTTAAGGACCTCAACGCTTGGGGGAGGA
CCGAAAAGAACCTCTTCTGGACACTGGCTGCTTTG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_005730 unedited
NNNNGGGGGGTGGGAGGTTTTTTAAACCCACTTTNTATAATTAATTGTAAGTAATACAAA
TATTCCAAAAATATAAACAGACACTTAATGGCGTCCTGCATTTCAAGTTTTTGAATACAA
CAAATTTATCAAACCATGAATCTGTAAGCAAGGTAGTCAGAATCCCATAGCCCAGTCACA
GTGGGAAGCAGATCCCCTACCCTCCAAATGGCATCTTGAAGGGGGAAAGCGGCACGAAAT
GGAACATGATAAGCAAAAAAGCTCACGAGGCCCAAAGAGGAGGGTCCGCTCCATGGGCAG
GCCCTACAACGTTAAAAGAATGGGGCAGCTGGCCCGACCTCTGGCCTCCTCTTCCCTGGC
TGAATGTAAATATTTACCAGCATTTAGAAAAAAGGAGAAAAAAGACAGAACTAAACCCGT
TTAGGAAAAAGGGACCGAGGGACAGCAGTGGTTAAGTAATCCACTGAGGACCTGAAGGGG
AAAATGGACTTACCTTTCTCATATACTTGGCCTGGCTAGGACACTGGGTGCCAGACAGCC
TTCTGAGGGGATTTTCTTTCTAAATGAGGCCTCAGGAACAGGTAGGGGCAGCAGAATAGA
ATAGCATCCATTTCCCAGAGAAAGACTGCCTTTACATTTCCCATGCTTTTAGCACAAAGC
AGCGTCTGGGCCACTGTTACCAGAGGTGAGTTTATACATTTACAAAATGCTTAANATCTT
TGGGAAGCAAGAGGAAGCTAAACAGAAGGTCCCATGTTAACTGAAGGCAAATTCACTCAA
CCTCTCTAGTAAGGGACCCATGGGCCTACAGAGTGTTTCCTCTACAATGTGCAGAGTGGA
AACCCTTACCTGAGCCTTTTCAGAAATGGTCCTGTGG
Restriction Sites ECoRI-NOT |
ACCN NM_005730
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_005730.2, NP_005721.2
RefSeq Size 4833 bp
RefSeq ORF 852 bp
Locus ID 10106
UniProt ID O14595
Cytogenetics 12q14.1
Domains CPDc
Protein Families Druggable Genome, Phosphatase
Summary Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_005730" in other vectors (5)
SKU Description Size Price
RC209026 CTDSP2 (Myc-DDK-tagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2) 10 ug
$300.00
RC209026L3 Lenti ORF clone of Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2), Myc-DDK-tagged 10 ug
$600.00
RC209026L4 Lenti ORF clone of Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2), mGFP tagged 10 ug
$600.00
RG209026 CTDSP2 (tGFP-tagged) - Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2) 10 ug
$489.00 $500.00
SC324051 CTDSP2 (untagged)-Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (CTDSP2) 10 ug
$300.00

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