BEX1 (NM_018476) Human Untagged Clone

SKU SC127703

BEX1 (untagged)-Human brain expressed, X-linked 1 (BEX1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: BEX1
• Synonyms: BEX2; HBEX2; HGR74-h
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127703 sequence for NM_018476 edited (data generated by NextGen Sequencing); ATGGAGTCCAAAGAGAAACGAGCAGTAAACAGTCTCAGCATGGAAAATGCCAACCAAGAA; AATGAAGAAAAGGAGCAAGTTGCTAATAAAGGGGAGCCCTTGGCCCTCCCTTTGGATGCT; GGTGAATACTGTGTGCCTAGAGGAAATCGTAGGCGGTTCCGCGTTAGGCAGCCCATCCTG; CAGTATAGATGGGATATGATGCATAGGCTTGGAGAACCACAGGCAAGGATGAGAGAAGAG; AATATGGAAAGGATTGGGGAGGAGGTGAGACAGCTGATGGAAAAGCTGAGGGAAAAGCAG; TTGAGTCATAGTCTGCGGGCAGTCAGCACTGACCCCCCTCACCATGACCATCATGATGAG; TTTTGCCTTATGCCCTGA; ; Clone variation with respect to NM_018476.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018476 unedited; TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGCTCCCCGCTGCCC; TGCGCTCGGCGCGCTGGCATCCGGCCCGGGGGAAAGCGGACCAGCCCTTCTGCAGGTCTG; CGGGGCCAAGTGTCCCGGCGGCGCACCTCGTGGCGAGAATCGGGAGAAGGAGGAGACTAC; AAGGATAGGCCCAGGAGTAATGGAGTCCAAAGAGAAACGAGCAGTAAACAGTCTCAGCAT; GGAAAATGCCAACCAAGAAAATGAAGAAAAGGAGCAAGTTGCTAATAAAGGGGAGCCCTT; GGCCCTCCCTTTGGATGCTGGTGAATACTGTGTGCCTAGAGGAAATCGTAGGCGGTTCCG; CGTTAGGCAGCCCATCCTGCAGTATAGATGGGATATGATGCATAGGCTTGGAGAACCACA; GGCAAGGATGAGAGAAGAGAATATGGAAAGGATTGGGGAGGAGGTGAGACAGCTGATGGA; AAAGCTGAGGGAAAAGCAGTTGAGTCATAGTCTGCGGGCAGTCAGCACTGACCCCCCTCA; CCATGACCATCATGATGAGTTTTGCCTTATGCCCTGAATCCTGATGGTTTCCCTAAAGTT; ATTACGGAAACAGACCCCTGCTTTCGATTTACATGTTCATGATGTGCCCTTGTTGTAAAC; CTTTACCTGTCACTTGTTTACGTGGNGTCTCCTATTACCAGCTTCTATTGAATATTNGNG; TTNTGAACCAGTCTGNTAGATTTTTGTTAGCAGAAGAATTTTACCTATTGCATGANAAGA; TGCTCATTATAAGTGAAAGTATAAAAGCACCTTTAANAAGCANAAAAAAAAAAAAACTCG; ACTCTAGATTGCGGNCGCGTCATAACTTGTTCTGAACAATCCGGNTGGGATCCTGGGAAC; CTCCCCATGC;
• Restriction Sites: NotI-NotI
• ACCN: NM_018476
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_018476.3, NP_060946.3
• RefSeq Size: 862 bp
• RefSeq ORF: 378 bp
• Locus ID: 55859
• UniProt ID: Q9HBH7
• Cytogenetics: Xq22
• Domains: BEX
• Summary: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).[UniProtKB/Swiss-Prot Function]