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WNT7B (NM_058238) Human Untagged Clone

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SKU
SC125825
WNT7B (untagged)-Human wingless-type MMTV integration site family, member 7B (WNT7B)
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol WNT7B
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_058238 edited
AGTCTGCCCGCAGCCCCCTGGCCCCTGCCCGGCCCTGCCGGGCCCGCGCGTCCCCTCCGG
CCGCCGCTGTCTATGGCGCAGCCCCCCTCCCTGGATCATGCACAGAAACTTTCGCAAGTG
GATTTTCTACGTGTTTCTCTGCTTTGGCGTCCTGTACGTGAAGCTCGGAGCACTGTCATC
CGTGGTGGCCCTGGGAGCCAACATCATCTGCAACAAGATTCCTGGCCTAGCCCCGCGGCA
GCGTGCCATCTGCCAGAGTCGGCCCGATGCCATCATTGTGATTGGGGAGGGGGCGCAGAT
GGGCATCAACGAGTGCCAGTACCAGTTCCGCTTCGGACGCTGGAACTGCTCTGCCCTCGG
CGAGAAGACCGTCTTCGGGCAAGAGCTCCGAGTAGGGAGCCGTGAGGCTGCCTTCACGTA
CGCCATCACCGCGGCTGGCGTGGCGCACGCCGTCACCGCTGCCTGCAGCCAAGGGAACCT
GAGCAACTGCGGCTGCGACCGCGAGAAGCAGGGCTACTACAACCAAGCCGAGGGCTGGAA
GTGGGGCGGCTGCTCGGCCGACGTGCGTTACGGCATCGACTTCTCCCGGCGCTTCGTGGA
CGCTCGGGAGATCAAGAAGAACGCGCGGCGCCTCATGAACCTGCATAACAATGAGGCCGG
CAGGAAGGTTCTAGAGGACCGGATGCAGCTGGAGTGCAAGTGCCACGGCGTGTCTGGCTC
CTGCACCACCAAAACCTGCTGGACCACGCTGCCCAAGTTCCGAGAGGTGGGCCACCTGCT
GAAGGAGAAGTACAACGCGGCCGTGCAGGTGGAGGTGGTGCGGGCCAGCCGTCTGCGGCA
GCCCACCTTCCTGCGCATCAAACAGCTGCGCAGCTATCAGAAGCCCATGGAGACAGACCT
GGTGTACATTGAGAAGTCGCCCAACTACTGCGAGGAGGACGCGGCCACGGGCAGCGTGGG
CACGCAGGGCCGTCTCTGCAACCGCACGTCGCCCGGCGCGGACGGCTGTGACACCATGTG
CTGCGGCCGAGGCTACAACACCCACCAGTACACCAAGGTGTGGCAGTGCAACTGCAAATT
CCACTGGTGCTGCTTCGTCAAGTGCAACACCTGCAGCGAGCGCACCGAGGTCTTCACCTG
CAAGTGAGGCCAGGCCCGGAGGCGGCCGCGGGCACCCTGGAACCCGGCGGCATTTTGCAC
ATCCACTCCTCACCTTCCCTGCCTTGGTGCTGCCAGCAGCAGACATAGACGGGTGCAGAA
GCGGGGAGCTCCAGGTGCAGGAGGGCACCGGCCGGGGCCCACGCCCTCTGCCCGCCTCCC
TGGGGCTCCTTCCTGCCACCTCCTCCCATCACCTCCTGCGGCAGAACAGCACCCGTGACC
CACCCAGAGAGCAAGGCCAGGGGCCTTGGTGCTCCCCGACGGGGCCCGGCAAGTTCTCTT
TCTTCTCTCTGGGAAAATGAACGTCCAGGACACACCTGTATCCCAGAGAGCAAAGTGATG
AGGAGACTGAGCGTCCCCAGCCCCACCTGGCGGCATGGACACAGAAAAGCTACGCCGGCT
GGCCTCTCCAGACCAGTTCCCAGGCTGGGTCTGCCGCTGGGCCCTGGGGCGGTGGGGACA
GATGTTGACACAAATTATTTATGTTTTCTTAGTATCAGAAGAGGATTCTCGGCACTAACA
CATAGCCAGTCCTAACTCCGTACTCTGTGTCAGCCCATCCCCTCGACACCCTCTGTTTCC
TTTCCCGGCCCCACCTGGCCGGCCCTCTGCCCCTGCAGAGCTGAGGCAGCCTGGGGTTGA
TGGGGACCACGCGGTGCCTGCAGGTCCTAGAAGTGAGCTGGGCAGGGGCTCTTCAGACCA
CACAGCCCTGACCGGGCCTTGGAGGAGAGCCATGGACAGGCTCCTCCATGCCGTCTTTCC
TTCTTTTGAAAATCCTATCAATGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACT
TTGGGAGACCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAAC
GTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGTGCACC
TGTAATCCCAGCTACTCAGGAGGCTGAGACAGGACACTTGCTTGAACCCGGGAGGTGGAG
GTTGCAATGAGCCAAGATTGTGCCACTGTATTCCAACCTGGGTGACAGAGCACGACTCTG
TCTCAAAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_058238 unedited
TGATTTTGTATACGACNACTATAGGCGGCCGCGTAATTCGCACGAGGAGTCTGCCCGCAG
CCCCCTGGCCCCTGCCCGGCCCTGCCGGGCCCGCGCGTCCCCTCCGGCCGCCGCTGTCTA
TGGCGCAGCCCCCCTCCCTGGATCATGCACAGAAACTTTCGCAAGTGGATTTTCTACGTG
TTTCTCTGCTTTGGCGTCCTGTACGTGAAGCTCGGAGCACTGTCATCCGTGGTGGCCCTG
GGAGCCAACATCATCTGCAACAAGATTCCTGGCCTAGCCCCGCGGCAGCGTGCCATCTGC
CAGAGTCGGCCCGATGCCATCATTGTGATTGGGGAGGGGGCGCAGATGGGCATCAACGAG
TGCCAGTACCAGTTCCGCTTCGGACGCTGGAACTGCTCTGCCCTCGGCGAGAAGACCGTC
TTCGGGCAAGAGCTCCGAGTAGGGAGCCGTGAGGCTGCCTTCACGTACGCCATCACCGCG
GCTGGCGTGGCGCACGCCGTCACCGCTGCCTGCAGCCAAGGGAACCTGAGCAACTGCGGC
TGCGACCGCGAGAAGCAGGGCTACTACAACCAAGCCNAGGGCTGGAATGTGGGCGGCTGC
TCGGCCGACGTGCGTTACGGCATCNACTTCTCCCGGCGCTTCGTGGACGCTCGGGAGATC
AAGAAGACGCGCGGCGCCTCATGAACCTGCATAACAATGAGGCCCGCAGGGAAGTTCTAG
AGGACCGATGCANNCTGAGTGCANGTGCCCACGCGTGTCTGGCTTCTGCACCAACAAAAC
TTGCTGGACACCCCTGCCCAGTTTCGAAAGGTGGCCACTTGCTTGAGGAGAAATACAACC
CGGCCCTCCAGTGGAGGGGTGCGGCCCACCCTTTGGGGGAGCCCACTTTCGGGGCATAAA
AACTGTGCACTTTAAAAACCTTGGAAACAAACCGGGGAACGTGGAAGTCCCAACT
Restriction Sites NotI-NotI |
ACCN NM_058238
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_058238.1, NP_478679.1
RefSeq Size 2250 bp
RefSeq ORF 1050 bp
Locus ID 7477
UniProt ID P56706
Cytogenetics 22q13.31
Protein Families Adult stem cells, Cancer stem cells, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway
Summary This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. provided by RefSeq, Oct 2008
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Documents
Resources
"NM_058238" in other vectors (6)
SKU Description Size Price
RC207691 WNT7B (Myc-DDK-tagged)-Human wingless-type MMTV integration site family, member 7B (WNT7B) 10 ug
$457.00
RC207691L1 Lenti ORF clone of Human wingless-type MMTV integration site family, member 7B (WNT7B), Myc-DDK-tagged 10 ug
$757.00
RC207691L2 Lenti ORF clone of Human wingless-type MMTV integration site family, member 7B (WNT7B), mGFP tagged 10 ug
$757.00
RC207691L3 Lenti ORF clone of Human wingless-type MMTV integration site family, member 7B (WNT7B), Myc-DDK-tagged 10 ug
$757.00
RC207691L4 Lenti ORF clone of Human wingless-type MMTV integration site family, member 7B (WNT7B), mGFP tagged 10 ug
$757.00
RG207691 WNT7B (tGFP-tagged) - Human wingless-type MMTV integration site family, member 7B (WNT7B) 10 ug
$489.00 $657.00

file-alt Citations

Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development
Afelik, Pool, Schmerr et al
Dev. Biol. (2015)
Cited by 66
AI Summary: In this study, the full-length human Wnt7b cDNA clone from OriGene Technologies was used to investigate the role of Wnt7b in pancreatic development, enabling the authors to assess how Wnt7b regulates progenitor cell growth and epithelial-to-mesenchymal signaling.
Snippet: These studies provide a basis for understanding Wnt7b-mediated organ growth, and uncover a novel epithelial-to-mesenchymal signaling pathway. Materials and Methods. Animals. The full length human Wnt7b cDNA clone was purchased from OriGene Technologies ... Related articles All 3 versions Cite SaveSaving
Showing 1-1 of 1 papers.
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