MAGEB2 (NM_002364) Human Untagged Clone
$480.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | MAGEB2 |
| Synonyms | CT3.2; DAM6; MAGE-XP-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_002364 |
| Insert Size | 960 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002364.4 |
| RefSeq Size | 1628 bp |
| RefSeq ORF | 960 bp |
| Locus ID | 4113 |
| UniProt ID | O15479 |
| Cytogenetics | Xp21.2 |
| MW | 35.3 kDa |
| Summary | This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_002364" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC205338 | MAGEB2 (Myc-DDK-tagged)-Human melanoma antigen family B, 2 (MAGEB2) | 10 ug |
$450.00
|
|
| RC205338L1 | Lenti ORF clone of Human melanoma antigen family B, 2 (MAGEB2), Myc-DDK-tagged | 10 ug |
$750.00
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|
| RC205338L2 | Lenti ORF clone of Human melanoma antigen family B, 2 (MAGEB2), mGFP tagged | 10 ug |
$750.00
|
|
| RC205338L3 | Lenti ORF clone of Human melanoma antigen family B, 2 (MAGEB2), Myc-DDK-tagged | 10 ug |
$750.00
|
|
| RC205338L4 | Lenti ORF clone of Human melanoma antigen family B, 2 (MAGEB2), mGFP tagged | 10 ug |
$750.00
|
|
| RG205338 | MAGEB2 (tGFP-tagged) - Human melanoma antigen family B, 2 (MAGEB2) | 10 ug |
$650.00
|
|
Citations
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1
Landegren, Sharon, Freyhult et al
Sci Rep (2016) 6, 20104 DOI: 10.1038/srep20104
Landegren, Sharon, Freyhult et al
Sci Rep (2016) 6, 20104 DOI: 10.1038/srep20104
Cited by 71
AI Summary: OriGene products, specifically the MAGEB2 and PDILT cDNA clones, were used in this study to validate and characterize novel autoantigens identified in APS1 patient sera.
MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma
Pattani, Soudry, Glazer et al
PLoS ONE (2012) 7 (9), e45534 DOI: 10.1371/journal.pone.0045534
Pattani, Soudry, Glazer et al
PLoS ONE (2012) 7 (9), e45534 DOI: 10.1371/journal.pone.0045534
Cited by 52
AI Summary: OriGene’s full-length ORF cDNA plasmid for MAGEB2 (SKU: SC122625) was used for transient transfection experiments to study the functional role of MAGEB2 in head and neck squamous cell carcinoma in this paper.
Snippet: A full-length ORF cDNA plasmids of MAGEAB2 (SKU: SC122625) was obtained for transient transfections from OriGene (Rockville, MD). ... function, and association between MAGE-A expression levels and resistance to etoposide treatment was shown in short- term melanoma
Showing 1-2 of 2 papers.
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