HEXIM2 (NM_144608) Human Untagged Clone

SKU SC120749

HEXIM2 (untagged)-Human hexamthylene bis-acetamide inducible 2 (HEXIM2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: HEXIM2
• Synonyms: L3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_144608, the custom clone sequence may differ by one or more nucleotides; ; ; ATGATGGCCACTCCGAACCAGACCGCCTGTAATGCAGAGTCACCAGTGGCCCTGGAGGAGGCCAAGACCT; CTGGTGCCCCGGGGAGCCCCCAAACACCCCCTGAGCGTCATGACTCTGGTGGTTCCCTGCCCCTGACACC; GCGGATGGAGAGCCACTCAGAGGATGAAGATCTTGCTGGGGCTGTCGGTGGCCTGGGCTGGAACAGTAGG; AGTCCCCGGACCCAGAGCCCAGGGGGCTGCTCAGCGGAGGCTGTGCTGGCCCGGAAGAAACACCGTCGGC; GGCCATCGAAGCGCAAAAGGCACTGGCGACCCTACCTGGAGCTGAGCTGGGCTGAGAAACAACAGCGGGA; TGAGAGGCAGAGCCAGAGGGCCTCCCGGGTCCGCGAAGAGATGTTCGCCAAAGGCCAGCCCGTGGCCCCC; TACAACACCACCCAGTTCCTGATGAATGACAGGGACCCGGAGGAGCCCAACTTGGATGTGCCCCATGGGA; TCTCCCACCCAGGTTCCAGTGGGGAGAGTGAGGCCGGGGACAGTGATGGGCGGGGCCGAGCGCACGGTGA; GTTCCAGCGGAAGGACTTCTCTGAGACTTACGAACGCTTCCACACCGAGAGCCTGCAGGGCCGCAGCAAG; CAGGAGCTGGTGCGAGACTACCTGGAGCTGGAGAAGCGGCTGTCGCAGGCGGAGGAGGAGACTAGGAGGC; TGCAGCAGCTGCAGGCGTGCACCGGCCAGCAGTCCTGCCGCCAGGTGGAGGAGCTGGCTGCCGAGGTCCA; GAGGCTCCGGACCGAAAACCAGCGGCTTCGTCAGGAGAACCAGATGTGGAACCGAGAGGGCTGCCGCTGT; GATGAGGAGCCGGGTACCTAG; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144608 unedited; GGAATTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGCGACATGCTA; GGTCAGGTTGTCCGGAGATCGGGGCTGAATGGGAGAGATCTTGAGGGCAAGAGCCTCAGA; GACCTTCAGGCACCGAGCTCGTGAAGGTTTCCAAGTGCCCCTCTCTAGCTGCTCCCAGGG; GGAATTAGTGGTTGCTACAGTAGTTTAAGAGGGTCGTGGTTTTTCGCAACCCGGGCGGCG; AGATGGCGCTTTGGTGTAAGCGAGGAGGACAGTACAGGACATGAGTCCTGGTGAGGGACC; CGAGGAGCAGGACAGAGAAGACGGCCCCTGAATCCCATTTGGCCCCTTGCTGGCTGGAGG; TGTGAAAACCAGCGGTGGAGGCAGCCTTCGGGGCCTGCATTTGAGAATAAGGGTGTCACT; AGTTCCAGGCGTCTGCTGAAAGATTTGGAACAGAAGATGATGGCCACTCCGAACCAGACC; GCCTGTAATGCAGAGTCACCAGTGGCCCTGGAGGAGGCCAAGACCTCTGGTGCCCCGGGG; AGCCCCCAAACACCCCCTGAGCGTCATGACTCTGGTGGTTCCCTGCCCCTGACACCGCGG; ATGGAGAGCCACTCAGAGGATGAAGATCTTGCTGGGGCTGTCGGTGGCCTGNGCTGGAAC; AGTANGAGTCCCCGGACCCAGAGCCCAGGGGGGCTGCTCAGNCGGAGCTGTGCTGGCCCG; GAAAGAACACCGTCGGCGGCCATCGAAGCGCAAAGGCACTGGCGACCCTACCTGGAGCTG; AGCTGGGCTGAGAAACACAGCGGGATGAGAAGCANAGCCCAGAGGCCTNCCGGNTCCGCG; AAGAGATGNTCGNCAAAGCCAGNCCGTGGNCCNCTACACACCACCCANTCCTGATAATGA; CAGGNACCCNGAGAGCCACTNGATGTGCCATGGGACTCCACCAGNNTCATGNGNAAATGA; GCCNGGAANTGAT;
• Restriction Sites: NotI-NotI
• ACCN: NM_144608
• Insert Size: 1650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_144608.1, NP_653209.1
• RefSeq Size: 1330 bp
• RefSeq ORF: 861 bp
• Locus ID: 124790
• UniProt ID: Q96MH2
• Cytogenetics: 17q21.31
• Protein Families: Transcription Factors
• Summary: This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]; Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same isoform (1).