CDS2 (NM_003818) Human Untagged Clone

SKU SC120671

CDS2 (untagged)-Human CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (CDS2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CDS2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120671 sequence for NM_003818 edited (data generated by NextGen Sequencing); ATGACAGAGCTGAGGCAGAGGGTGGCCCATGAGCCGGTTGCGCCACCCGAGGACAAGGAG; TCAGAGTCAGAAGCAAAGGTAGATGGAGAGACTGCATCGGACAGTGAGAGCCGGGCAGAA; TCCGCACCCCTGCCAGTCTCTGCAGATGATACCCCGGAGGTCCTCAATAGGGCCCTTTCC; AACTTGTCTTCAAGATGGAAGAACTGGTGGGTGAGAGGCATCCTGACTTTGGCCATGATT; GCATTTTTCTTCATCATCATTTACCTGGGACCAATGGTTTTGATGATAATCGTGATGTGC; GTTCAGATTAAGTGTTTCCATGAGATAATCACTATTGGCTACAACGTCTACCACTCATAT; GATCTGCCCTGGTTCAGGACGCTCAGCTGGTACTTTCTCCTGTGTGTAAACTATTTCTTC; TATGGTGAGACAGTGACGGATTACTTCTTCACCCTGGTCCAGAGAGAAGAGCCTTTGCGG; ATTCTCAGTAAATACCACCGGTTCATTTCCTTTACTCTCTATCTAATAGGATTCTGCATG; TTTGTACTGAGTCTGGTCAAGAAGCATTATCGACTGCAGTTCTACATGTTTGGCTGGACC; CATGTGACATTGCTGATTGTTGTAACACAGTCACATCTTGTTATCCACAACCTATTTGAA; GGAATGATCTGGTTCATTGTCCCCATATCTTGTGTGATCTGTAATGACATCATGGCCTAT; ATGTTTGGCTTTTTCTTTGGTCGGACCCCACTCATCAAGCTGTCCCCGAAGAAGACCTGG; GAAGGCTTCATTGGGGGCTTCTTTGCTACTGTGGTGTTTGGCCTTCTGCTGTCCTATGTG; ATGTCCGGGTACAGATGCTTTGTCTGCCCTGTGGAGTACAACAATGACACCAACAGCTTC; ACTGTGGACTGTGAGCCCTCGGACCTGTTTCGCCTGCAGGAGTACAACATTCCTGGGGTG; ATCCAGTCAGTCATTGGCTGGAAAACGGTCCGGATGTACCCCTTCCAGATTCACAGCATC; GCTCTCTCCACCTTTGCCTCGCTCATTGGCCCCTTTGGAGGATTCTTCGCAAGTGGATTC; AAACGAGCCTTTAAAATCAAAGACTTTGCCAATACCATTCCTGGCCATGGAGGCATCATG; GATCGCTTTGACTGCCAGTATCTGATGGCCACCTTTGTCAATGTATACATCGCCAGTTTT; ATCAGAGGCCCTAACCCAAGCAAACTGATTCAGCAGTTCCTGACTTTACGGCCAGATCAG; CAGCTCCACATCTTCAACACGCTGCGGTCTCATCTGATCGACAAAGGGATGCTGACATCC; ACCACAGAGGACGAGTAG; ; Clone variation with respect to NM_003818.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003818 unedited; NGGTCACTTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGCTGGGCTGC; TAAGGGAACTGTGAGCCGCTCAGAGCCGCGCGCCTCCCGGGCGGGGCGGGGCCGGCCGTG; GGAGTCCGCGCGTGCCCGCGCCGAGCTGCCTGCTCCGGCGGCTTCGCTGCTAGCTCGCGG; CGACGTCGGGCCGATTTTCCCAGGATGACAGAGCTGAGGCAGAGGGTGGCCCATGAGCCG; GTTGCGCCACCCGAGGACAAGGAGTCAGAGTCAGAAGCAAAGGTAGATGGAGAGACTGCA; TCGGACAGTGAGAGCCGGGCAGAATCCGCACCCCTGCCAGTCTCTGCAGATGATACCCCG; GAGGTCCTCAATAGGGCCCTTTCCAACTTGTCTTCAAGATGGAAGAACTGGTGGGTGAGA; GGCATCCTGACTTTGGCCATGATTGCATTTTTCTTCATCATCATTTACCTGGGACCAATG; GTTTTGATGATAATCGTGATGTGCGTTCAGATTAAGTGTTTCCATGAGATAATCACTATT; GGCTACAACGTCTACCACTCATATGATCTGCCCTGGTTCAGGACGCTCAGCTGGTACTTT; CTCCTGTGTGTAAACTATTTCTTCTATGGTGAGACAGTGACGGATTACTTCTTCACCCTG; GTCCAGAGAGAAGAGCCTTTGCGGATTCTCAGTAAATACCACCGGTTCATTTCCTTTACT; CTCTATCTAATAGGATTCTGCATGTTTGTACTGAGTCTGGTCAAGAAGCATTATCGACTG; CAGTTCTACATGTTTGGGCTGGACCCATGTGACATTGCTGATTGGTGTAACACAGTCACA; TCTTGTTATCCACAACCTATTTGAAGGAATGATCTGGNTCATTGTCCCATATCTTGTGTG; ATCTGTAATGACATCATGCNCCTATATGTTG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003818 unedited; NNTTTTCGCTCTGGACCCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTAC; ACATTATATAAAAGTGTGCATTTAATCTTCAAAATAGTCAAGGCTCTAATCAGGTTAGGT; TTTCCATAGTTTTAAGCAGGACTTTGTGGTTTTAGTGAAGAAGTCATGGTGCAATTGAAA; TCACTGTAAGAAATAAGTGACTTTTAAAACAAACACAGACACACACACTCCTCTTAAGAG; TAATATATACACAACACAGCAGCTACATGGGTGTTCAGGCAAAGGGTGCATGAACGAGAA; GCCCTCTGCTCCCTGCCCGATGAGAAAGTCCCCAGAAAGGATTCAGCAGCAGCAAGTCTA; CAGCACAAACATGGATGGCATTGTCCCTGAAAACACACAGTTAGGTGGACCTACAGGAGA; CATTGGAGCCTAGACATGTGGGAAAGGGCTCAGTTACAGTACATTCTACTGCATACACTT; GAAATATTACAGTGTGTTTTTTCTCCAGACTATTATAAATAATTTTTCGTGCTTTCTGAA; AAAAATAAAAACTGAAACTTTCAGTCTGCGATGAAGGTGAACCCATCTTATAAAGCAGAG; CTTACTTACATTCTGCAGGATTTTGGTGTGGATGCATAGAAGGCTTACCTGGTTAGTAAG; CCTCCATTCCTCCGACCTACAGAAGGCAACCCTTCTGCAGCTCCAAGCAGGGATTTCTAG; AAAAGACCAGGTGTACAAAACATCTAAGCTGTGCCCTCCACCCACAGTGGGGAAGTCCCC; TGATTGGTCAGACCAGATGATGTCTGTGTCTGACTGACCCCAAAACAGTTCATTTGTGGG; GGCTGGAACCACCAAAAAACCTTCTGACCTGGGCAACATTGCTTCCAAATATTATACTTT; TGTA;
• Restriction Sites: NotI-NotI
• ACCN: NM_003818
• Insert Size: 2770 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003818.2, NP_003809.1
• RefSeq Size: 2711 bp
• RefSeq ORF: 1338 bp
• Locus ID: 8760
• UniProt ID: O95674
• Cytogenetics: 20p12.3
• Domains: CTP_transf_1
• Protein Families: Transmembrane
• Protein Pathways: Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Summary: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]