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DR1 (NM_001938) Human Untagged Clone

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SKU
SC118958
DR1 (untagged)-Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1)
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol DR1
Synonyms NC2; NC2-BETA; NC2B; NCB2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_001938, the custom clone sequence may differ by one or more nucleotides


ATGGCTTCCTCGTCTGGCAACGATGATGATCTCACTATCCCCAGAGCTGCTATCAATAAAATGATCAAAG
AGACTCTTCCTAATGTCCGGGTGGCCAACGATGCTCGAGAGCTGGTGGTGAACTGCTGCACTGAATTCAT
TCACCTTATATCTTCTGAAGCCAATGAGATTTGTAACAAATCGGAAAAGAAGACCATCTCACCAGAGCAT
GTCATACAAGCACTAGAAAGTTTGGGATTTGGCTCTTACATCAGTGAAGTAAAAGAAGTCTTGCAAGAGT
GTAAAACAGTAGCATTAAAAAGAAGAAAGGCCAGTTCTCGTTTGGAAAACCTTGGCATTCCTGAAGAAGA
GTTATTGAGACAGCAACAAGAATTATTTGCAAAAGCTAGACAGCAACAAGCAGAATTGGCCCAACAGGAA
TGGCTTCAAATGCAGCAAGCTGCCCAACAAGCCCAGCTTGCTGCTGCCTCAGCCAGTGCATCTAATCAGG
CGGGATCTTCTCAGGATGAAGAAGATGATGATGATATCTGA

5' Read Nucleotide Sequence
>OriGene 5' read for NM_001938 unedited
AATCGACTCATAAGGGCGGCCGCGAATTCGGCACGAGGCACACGCGAGTGTTCCCAGCCC
TCAAGCCAGCTGCTCCTCCGTTCATTTTCTGCACCCTCTTCGCAAAGCACCCCCCGGGAT
CACTTCTCCGAGGGCGAACTTTTTGAGAAATCTCGGTGGAGTAGTGGACCAGAGCTGGGG
AGTTTTTAAAAGCCGGGGCGCGAGAAAAGGAAGGTACTATGGCTTCCTCGTCTGGCAACG
ATGATGATCTCACTATCCCCAGAGCTGCTATCAATAAAATGATCAAAGAGACTCTTCCTA
ATGTCCGGGTGGCCAACGATGCTCGAGAGCTGGTGGTGAACTGCTGCACTGAATTCATTC
ACCTTATATCTTCTGAAGCCAATGAGATTTGTAACAAATCGGAAAAGAAGACCATCTCAC
CAGAGCATGTCATACAAGCACTAGAAAGTTTGGGATTTGGCTCTTACATCAGTGAAGTAA
AAGAAGTCTTGCAAGAGTGTAAAACAGTAGCATTAAAAAAGAAAAAAGGCCAGTTCTCGT
TTGGAAAACCTTGGCATTCCTGAAGAAAAATTATTGAGACAGCAACAAGAATTATTTGCA
AAAGCTAGACAGCAACAAGCAGAATTGGCCCAACAGGAATGGCTTCAAATGCAGCAAGCT
GCCCAACAAGCCCAGCTTGCTGCTGCCTCAGCCAGTGCATCTAATAGGGCGGGATCTTCT
CAGATGAAAAAAAGATGATGATATCTGAAATTCACAGCTGAGTTCTATTTCTTTAATAAT
GTTNNTCNCTGACAACAAAAAAGTGAAGAAATGCTAATCTGTATTNTGTATGCATCTGGN
NGGGACTGTCATTGTATCTAAGGGATGCTGCTATAAAGTCATCNATNGGNGCTATAAGNA
AAACTGCTCTTTGACATGAAAAATTAGGNTAGATATATCATNTGATNTTTAA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001938 unedited
GTACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTAAAACACATCAC
AATTTTATTGCTTGAAGATACAGCATATGAAATCACAAGAATGTCAAAATGAAAAGTCAC
TAGGCTTCAAACGTATAATACATTATCAGATGCAGTAAAATATTAACCTGAACTCTGCAT
CAGAAAAAAAAAAAAAAGTGTGGAAAATATCTAAGTTGTTTACCCTTAAGAAACAGATAT
ACTTAAAATAGAAAGTATAAGGATGTTACAGTACAAATTAGAAAAGCCAACACGTATTAA
CTTATCGTTCTAGACTAAACTACCTTTGGTACTTAAACTTTTTAAAAAACAATTTCTATC
TCATCCAAATGCACTTCATGGGTATGACATCCATGAAGTAACTTTCACTTAAACATTCAG
CANAATTAACCTTTTCACTTCATGGGGGAANGTATATTTAATAAATGTATAACAANTATT
TCCCTTTTACTAAAACTGCAAAATATGATCATTAAGAAACCTAACAGTTATAAAACTTTA
CTTACTTAGCTCTNCATTTAAAATGGGAATCCTGGAGGCACAATCTATTTTTGGGCTNGG
TGAATACATAAGTTAANAAGATTGGGCACTGACATAGAATTAATACTTATACTATCTAGN
GACTTTTCCTTCTGGTTCAAATATGAACATATGCCTTTCTTCACTCCTGAATTCTATATA
CTACATACTGTATTATTAAACCAATTAAGCTCTCTACAGCAGGTGAACTTTTATGTTCTA
TTCGCTGATAGTTTACCCAACTATGTCATTAGCTGACAATAATCTTAGGGTGACAATGAA
AAACTNTTAACAAATAATTTTTTTAGCCTCCCTATTGGGACATATTGCTCTAAAGGAGTT
GACTCGCCTTTTTGGGAAGGTATGTTTTAAACTAGNACTACCCCGTATAAACCTTTTACA
GTGCTT
Restriction Sites NotI-NotI |
ACCN NM_001938
Insert Size 2800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001938.2, NP_001929.1
RefSeq Size 3222 bp
RefSeq ORF 531 bp
Locus ID 1810
UniProt ID Q01658
Cytogenetics 1p22.1
Domains CBFD_NFYB_HMF
Protein Families Transcription Factors
Summary This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. provided by RefSeq, Jul 2008
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Documents
Resources
"NM_001938" in other vectors (6)
SKU Description Size Price
RC205733 DR1 (Myc-DDK-tagged)-Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1) 10 ug
$300.00
RC205733L1 Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), Myc-DDK-tagged 10 ug
$600.00
RC205733L2 Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mGFP tagged 10 ug
$600.00
RC205733L3 Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), Myc-DDK-tagged 10 ug
$600.00
RC205733L4 Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mGFP tagged 10 ug
$600.00
RG205733 DR1 (tGFP-tagged) - Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1) 10 ug
$489.00 $500.00

file-alt Citations

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