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MAL (NM_002371) Human Untagged Clone

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SKU
SC118699
MAL (untagged)-Human mal, T-cell differentiation protein (MAL), transcript variant a
  $150.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol MAL
Synonyms MVP17; VIP17
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_002371, the custom clone sequence may differ by one or more nucleotides


ATGGCCCCCGCAGCGGCGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACCACCTTGCCCG
ACTTGCTCTTCATCTTTGAGTTTATCTTCGGGGGCCTGGTGTGGATCCTGGTGGCCTCCTCCCTGGTGCC
CTGGCCCCTGGTCCAGGGCTGGGTGATGTTCGTGTCTGTGTTCTGCTTCGTGGCCACCACCACCTTGATC
ATCCTGTACATAATTGGAGCCCACGGTGGAGAGACTTCCTGGGTCACCTTGGACGCAGCCTACCACTGCA
CCGCTGCCCTCTTTTACCTCAGCGCCTCAGTCCTGGAGGCCCTGGCCACCATCACGATGCAAGACGGCTT
CACCTACAGGCACTACCATGAAAACATTGCTGCCGTGGTGTTCTCCTACATAGCCACTCTGCTCTACGTG
GTCCATGCGGTGTTCTCTTTAATCAGATGGAAGTCTTCATAA

5' Read Nucleotide Sequence
>OriGene 5' read for NM_002371 unedited
CTNTGAGGGNCGGCACGCGCAATTCGGCACGAGGGCCAGCGAGAGGTCTGCGCGGAGTCT
GAGCGGCGCTCGTCCCGTCCCAAGGCCGACGCCAGCACGCCGTCATGGCCCCCGCAGCGG
CGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACCACCTTGCCCGACTTGC
TCTTCATCTTTGATTTTATCTTCGGGGGCCTGGTGTGGATCCTGGTGGCCTCCTCCCTGG
TGCCCTGGCCCCTGGTCCAGGGCTGGGTGATGTTCGTGTCTGTGTTCTGCTTCGTGGCCA
CCACCACCTTGATCATCCTGTACATAATTGGAGCCCACGGTGGAGAGACTTCCTGGGTCA
CCTTGGACGCAGCCTACCACTGCACCGCTGCCCTCTTTTACCTCAGCGCCTCAGTCCTGG
AGGCCCTGGCCACCATCACGATGCAAGACGGCTTCACCTACAGGCACTACCATGAAAACA
TTGCTGCCGTGGTGTTCTCCTACATAGCCACTCTGCTCTACGTGGTCCATGCGGTGTTCT
CTTTAATCAGATGGAAGTCTTCATAAAGCCGCAGTAGAACTTGAGCTGAAAACCCAGATG
GTGTTAACTGGCCGCCCCACTTTCCGGCATAACTTTTTAGAAAACAGAAATGCCCTTGAT
GGTGGAAAAAAGAAAACAACCACCCCCCCACTGCCCAAAAAAAAAGCCCTGCCCTGTTGC
TCGTGGGTGCTGTGTTTACTCTCCCGTGTGCCTTCGCGTCCGGGTTGGGAGCTTGCTGTG
TCTAACCTCCAACTGCTGTGCTGTCTGCTAGGGTCACCTCCTGTTTGTGAAGGGNGACCT
NNCTGTCGGGGGTGGGAAGTGGCGACCGTGACCTGAGAAGGAAGAAAGAA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_002371 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTGAACATTAAAACATTT
TATAAAGTATTTCACAGGGTTATCGTCTTCCACCATGGACCTCTGGAAAGATCTGTTGGG
TGAGTTTTAGTCCCCATGACATGCAGAACATCCATGAAGACTTAAAACATGGCACAAGAT
GGGGCGCTCGGGAGAGCTTGTGGACAATACCAACAGGTAGTTCTCGAGAGCTGCTCCAGG
GGTCAGCAGAGGATCTTTCTTTCCTTCTCAGGTCACGGTCGCCACTTCCCACCCCCGAAC
AAGAAGGTCCCCTTTCACAAACAGGAGGTGACCCTAGCAGACAGCACAGCAGTTGGAGGT
TAGACACAGCAAGCTCCCAACCCGGACGCGAAGGCACACGGGAGAGTAAACACAGCACCC
ACGAGCAACAGGGCAGGGCTTTTTTTTTTGGGCAGTGGGGGTGGGGGTTGTTTTCTTTTT
TCCACCATCAAGGGCATTTCTGTTTTCTAAAAAGTTATGCCGGAAAGTGGGGCGGCCAGT
TAACACCATCTGGGTTTTCAGCTCAAGTTCTACTGCGGCTTTATGAAGACTTCCATCTGA
TTAAAGAGAACACCGCATGGACCACGTAGAGCAGAGTGGCTATGTAGGAGAACACCACGG
CAGCAATGTTTTCATGGTAGTGCCTGTANGTGAAGCCGTCTTGCATCGTGATGGTGGCCA
GGGCCTNCAGGACTGAGGCGCTGAGGTAAAAGAAGGGCACGGTGCANTGGTAGGCTGCGT
CCAAGGTGACCCAGGAAGTCTCTCCACCGTGGCTCCATTATGTCAGGATGATCAAGGGGG
GGGTGGCCCNAANCAAACACAGACACGACATTACCAACCCTGAACCGGGGCCAGGCCCAG
GGAGGAGGCCCCAGATCCCACCAGCCCCGAAAATACTCAAATGAGAAAA
Restriction Sites NotI-NotI |
ACCN NM_002371
Insert Size 1000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002371.2, NP_002362.1
RefSeq Size 1056 bp
RefSeq ORF 462 bp
Locus ID 4118
UniProt ID P21145
Cytogenetics 2q11.1
Protein Families Transmembrane
Summary The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. provided by RefSeq, May 2012
Transcript Variant: This variant (a) includes both alternatively spliced exons 2 and 3, resulting in the longest isoform (a).
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Documents
Resources
"NM_002371" in other vectors (6)
SKU Description Size Price
RC201256 MAL (Myc-DDK-tagged)-Human mal, T-cell differentiation protein (MAL), transcript variant a 10 ug
$289.00
RC201256L1 Lenti ORF clone of Human mal, T-cell differentiation protein (MAL), transcript variant a, Myc-DDK-tagged 10 ug
$450.00
RC201256L2 Lenti ORF clone of Human mal, T-cell differentiation protein (MAL), transcript variant a, mGFP tagged 10 ug
$450.00
RC201256L3 Lenti ORF clone of Human mal, T-cell differentiation protein (MAL), transcript variant a, Myc-DDK-tagged 10 ug
$450.00
RC201256L4 Lenti ORF clone of Human mal, T-cell differentiation protein (MAL), transcript variant a, mGFP tagged 10 ug
$450.00
RG201256 MAL (tGFP-tagged) - Human mal, T-cell differentiation protein (MAL), transcript variant a 10 ug
$489.00

file-alt Citations

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