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MSX1 (NM_002448) Human Untagged Clone

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SKU
SC118632
MSX1 (untagged)-Human msh homeobox 1 (MSX1)
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol MSX1
Synonyms ECTD3; HOX7; HYD1; STHAG1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_002448 edited
CCGGCCGCGCTCCCAGCCCGCCCGGAGCCCATGCCCGGCGGCTGGCCAGTGCTGCGGCAG
AAGGGGGGGCCCGGCTCTGCATGGCCCCGGCTGCTGACATGACTTCTTTGCCACTCGGTG
TCAAAGTGGAGGACTCCGCCTTCGGCAAGCCGGCGGGGGGAGGCGCGGGCCAGGCCCCCA
GCGCCGCCGCGGCCACGGCAGCCGCCATGGGCGCGGACGAGGAGGGGGCCAAGCCCAAAG
TGTCCCCTTCGCTCCTGCCCTTCAGCGTGGAGGCGCTCATGGCCGACCACAGGAAGCCGG
GGGCCAAGGAGAGCGCCCTGGCGCCCTCCGAGGGCGTGCAGGCGGCGGGTGGCTCGGCGC
AGCCACTGGGCGTCCCGCCGGGGTCGCTGGGAGCCCCGGACGCGCCCTCTTCGCCGCGGC
CGCTCGGCCATTTCTCGGTGGGGGGACTCCTCAAGCTGCCAGAAGATGCGCTCGTCAAAG
CCGAGAGCCCCGAGAAGCCCGAGAGGACCCCGTGGATGCAGAGCCCCCGCTTCTCCCCGC
CGCCGGCCAGGCGGCTGAGCCCCCCAGCCTGCACCCTCCGCAAACACAAGACGAACCGTA
AGCCGCGGACGCCCTTCACCACCGCGCAGCTGCTGGCGCTGGAGCGCAAGTTCCGCCAGA
AGCAGTACCTGTCCATCGCCGAGCGCGCGGAGTTCTCCAGCTCGCTCAGCCTCACTGAGA
CGCAGGTGAAGATATGGTTCCAGAACCGCCGCGCCAAGGCAAAGAGACTACAAGAGGCAG
AGCTGGAGAAGCTGAAGATGGCCGCCAAGCCCATGCTGCCACCGGCTGCCTTCGGCCTCT
CCTTCCCTCTCGGCGGCCCCGCAGCTGTAGCGGCCGCGGCGGGTGCCTCGCTCTACGGTG
CCTCTGGCCCCTTCCAGCGCGCCGCGCTGCCTGTGGCGCCCGTGGGACTCTACACGGCCC
ATGTGGGCTACAGCATGTACCACCTGACATAGAGGGTCCCAGGTCGCCCACCTGTGGGCC
AGCCGATTCCTCCAGCCCTGGTGCTGTACCCCCGACGTGCTCCCCTGTTCGGCACCGCCA
GCCGCCTTCCCTTTAACCCTCACACTGCTCCAGTTTCACCTCTTTGCTCCCTGAGTTCAC
TCTCCGAAGTCTGATCCCTGCCAAAAAGTGGCTGGAAGAGTCCCTTAGTACTCTTCTAGC
ATTTAGATCTACACTCTCGAGTTAAAGATGGGGAAACTGAGGGCAGAGAGGTTAACAGAT
TTATCTAGGGTCCCCAGCAGAATTGACAGTTGAACAGAGCTAGAGGCCATGTCTCCTGCA
TAGCTTTTCCCTGTCCTGACACCAGGCAAGAAAAGCGCAGAGAAATCGGTGTCTGACGAT
TTTGGAAATGAGAACAATCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_002448 unedited
AAAAAAAAAAAAAAAAAAAAATAAAAAACNCTGTTAGATTTGTAAACGATCCTATAGGCG
GCCGCGAAATTCGCACGAGAAGCCGGCCGCGCTCCCAGCCCGCCCGGTACCCATGCCCGG
CGGCTGGCCAGTGCTGCGGCAGAAGGGGGGGCCCGGCTCTGCATGGCCCCGGCTGCTGAC
ATGACTTCTTTGCCACTCGGTGTCAAAGTGGAGGACTCCGCCTTCGGCAAGCCGGCGGGG
GGAGGCGCGGGCCAGGCCCCCAGCGCCGCCGCGGCCACGGCAGCCGCCATGGGCGCGGAC
GAGGAGGGGGCCAAGCCCAAAGTGTCCCCTTCGCTCCTGCCCTTCAGCGTGGAGGCGCTC
ATGGCCGACCACAGGAAGCCGGGGGCCAAGGAGAGCGCCCTGGCGCCCTCCGAGGGCGTG
CAGGCGGCGGGTGGCTCGGCGCAGCCACTGGGCGTCCCGCCGGGGTCGCTGGGAGCCCCG
GACGCGCCCTCTTCGCCGCGGCCGCTCGGCCATTTCTCGGTGGGGGGACTCCTCAAGCTG
CCAGAAGATGCGCTCGTCAAAGCCCGAGAGCCCCGAGAAGCCCGAGAGGACCCCGTGGAT
GCAGAAGCCCCGCTTCTCCCCGCCGCCGGCCAGGCGGCTGAGCCCCCCAGCCTGCACCCC
TTCGCAAACACAAGACGAACCCGTAGCCGCGGACGCCCTTCACCACCGCGCACCTGCTGG
CGCTGAACCCAAGTTCCGCCAAAACAGTACCTGTCCATCGCCGAGCGCGCGGAGTTCTCC
AGCTCGCTCAACCTCACTGAGACCCAGGTGAGGAAATGGTTCCAGAACCGCCCGGCCCAG
GCAAAGAAACTACCAGAGGCCCAACCTGGACAACCTGAATAAGGCCCCCAGCCCATGCTG
CCACCGGTTGTCTTTGGCCTTTCTTTCCTTT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_002448 unedited
GGGCTATTGGGCGTGGCCACTTGCCATGNCCGGGANAGCACTGGGGNAGGGTCACAGGGC
TGCCACCCGGGCTCTGTTGCAGCAAACAGCTATGACCGCGGCCGCAATCTAGTAGTCGAG
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATTGTTCTCATTTCCAAAATCGTCAGA
CACCGTTTTCTCTGCGCTTTTCTTGCCTGGTGTCAGGACAGGGAAAAGCTATGCAGGAGA
CATGGCCTCTAGCTCTGTTCAACTGTCAATTCTGCTGGGGACCCTAGATAAATCTGTTAA
CCTCTCTGCCCTCAGTTTCCCCATCTTTAACTCGAGAGTGTATATCTAAATGCTAGAAGA
GTACTAAGGGACTCTTCCAGCCACTTTTTGGCAGGGATCAGACTTCGGAGAGTGAACTCA
GGGAGCAAAGAGGTGAAACTGGAGCAGTGTGAGGGTTAAAGGGAAAGCGGCTGGCGGTGC
CCAACAGGGGAGCACGTCGGGGGTACAGCACCAGGGCTGGAGGAATCGGCTGGCCCACAG
GTGGGCGACCTGGGACCCTCTATGTCAGGTGGTACATGCTGTAGCCCACATGGGCCGTGT
AGAGTCCCACGGGCGCCACAGGCAGCGCGGCGCGCTGGAAGGGGCCAGAGGCACCGTAGA
GCGAGGCACCCGCCGCGGCCGCTACAGCTGCGGGGCCCCCTAGAGGGAAGGAGAGGCCNA
AGGCACCCGTGGCAACATGGGCTTGGCGGCCATCTTCAGCTTCTCCAGCTCTGCCTCTTG
TAGTCTCTTTGCCTTGGCGCGGCGGTTCTGGAACCATATCTTCCCCTGCGTCTCANTGAA
GCTGAGCGAGCTGGAAAACCCCCGCGCTCGGCGATGGGACAGGTCTGCTTCTGGCAGACT
TGCGCTCCCACGCCGCACG
Restriction Sites NotI-NotI |
ACCN NM_002448
Insert Size 1500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002448.3.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002448.1, NP_002439.1
RefSeq Size 1713 bp
RefSeq ORF 894 bp
Locus ID 4487
UniProt ID P28360
Cytogenetics 4p16.2
Domains homeobox
Protein Families Druggable Genome, Transcription Factors
Summary This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. provided by RefSeq, Jul 2008
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Documents
Resources
"NM_002448" in other vectors (7)
SKU Description Size Price
RC205682 MSX1 (Myc-DDK-tagged)-Human msh homeobox 1 (MSX1) 10 ug
$450.00
RC205682L1 Lenti ORF clone of Human msh homeobox 1 (MSX1), Myc-DDK-tagged 10 ug
$750.00
RC205682L2 Lenti ORF clone of Human msh homeobox 1 (MSX1), mGFP tagged 10 ug
$750.00
RC205682L3 Lenti ORF clone of Human msh homeobox 1 (MSX1), Myc-DDK-tagged 10 ug
$750.00
RC205682L4 Lenti ORF clone of Human msh homeobox 1 (MSX1), mGFP tagged 10 ug
$750.00
RG205682 MSX1 (tGFP-tagged) - Human msh homeobox 1 (MSX1) 10 ug
$650.00
SC317449 MSX1 (untagged)-Human msh homeobox 1 (MSX1) 10 ug
$330.00

file-alt Citations

NKL homeobox gene activities in B-cell development and lymphomas
Nagel, MacLeod, Meyer et al
PLoS ONE (2018) 13 (10), e0205537 DOI: 10.1371/journal.pone.0205537
AI Summary: OriGene contributed gene expression constructs for HHEX, HLX, MSX1, and PCGF5 (cloned in vector pCMV6-XL4), which were used to analyze the roles of these genes in B-cell development and lymphomas.
Snippet: obtained from Qiagen (Hilden, Germany). Gene expression constructs for HHEX, HLX, MSX1 and PCGF5 were cloned in vector pCMV6-XL4 and obtained from Origene (Wiesbaden, Germany). SiRNAs (80 pmol) and expression Cached
FigureFigureFigure
A novel non-stop mutation in MSX1 causing autosomal dominant non-syndromic oligodontia
Wong, Liu, Han et al
Mutagenesis (2014)
Cited by 38
AI Summary: OriGene's human MSX1 cDNA (NM_002448) was used to generate expression constructs for functional studies of the novel MSX1 mutation described in the paper.
Snippet: The human MSX1 cDNA (accession number: NM_002448;Origene, Rockville, MD, USA) was cloned into pcDNA3.1 expression vector (Invitrogen, Grand Island, NY, USA) and pcDNA3.1-MSX1 was generated, incorporating a Myc epitope tag at the C-terminus of MSX1 ... Cite SaveSaving
Showing 1-2 of 2 papers.
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