PMP2 (NM_002677) Human Untagged Clone

SKU SC118506

PMP2 (untagged)-Human peripheral myelin protein 2 (PMP2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: PMP2
• Synonyms: CMT1G; FABP8; M-FABP; MP2; P2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118506 sequence for NM_002677 edited (data generated by NextGen Sequencing); ATGAGCAACAAATTCCTGGGCACCTGGAAACTTGTCTCTAGTGAGAACTTTGACGATTAC; ATGAAAGCTCTGGGTGTGGGGTTAGCCACCAGAAAACTGGGAAATTTGGCCAAACCCACT; GTGATCATCAGCAAGAAAGGAGATATTATAACTATACGAACTGAAAGTACCTTTAAAAAT; ACAGAGATCTCCTTCAAGCTAGGCCAGGAATTTGAAGAAACCACAGCTGACAATAGAAAG; ACCAAGAGCATCGTAACCCTGCAGAGAGGATCACTGAATCAAGTGCAGAGATGGGATGGC; AAAGAGACAACCATAAAGAGAAAGCTAGTGAATGGGAAAATGGTAGCGGAATGTAAAATG; AAGGGCGTGGTGTGCACCAGAATCTATGAGAAGGTCTGA; ; Clone variation with respect to NM_002677.3; 186 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002677 unedited; GTTAGCATTTGTATACGACTCATATAGGCGGCCGCGCAATTCGCACGAGGCGATGAGCAA; CAAATTCCTGGGCACCTGGAAACTTGTCTCTAGTGAGAACTTTGACGATTACATGAAAGC; TCTGGGTGTGGGGTTAGCCACCAGAAAACTGGGAAATTTGGCCAAACCCACTGTGATCAT; CAGCAAGAAAGGAGATATTATAACTATACGAACTGAAAGTACCTTTAAAAATACAGAGAT; CTCCTTCAAGCTAGGCCAGGAATTTGAAGAAACCACAGCTGACAATAGAAAGACCAAGAG; CATCGTAACCCTGCAGAGAGGATCACTGAATCAAGTGCAGAGATGGGATGGCAAAGAGAC; AACCATAAAGAGAAAGCTAGTGAATGGGAAAATGGTAGCGGAATGTAAAATGAAGGGCGT; GGTGTGCACCAGAATCTATGAGAAGGTCTGAAAAATCATTTCCTCATTGAAGTGGCTTTT; TATCATTTAATGATGGAAATCAATTGCTTCCATTGACAAAACTGAATACACTGCAAATAT; TTGTTTTTGCTTTTGTCTTAATATACCAGATATGCAAAGGCCTAAACTGAGAATTAATCT; AAAAGTCAGTGTTATTTAAACATTTTCAATGTGCATGCATGTCATTATTACATCAAAGCA; TATATATTGGCCAGACACAAACAGTTGATGATGTCATTCAATTAACTACAAAATTCTAAT; CTATGTTGAACTTTGTATACTTGAAATGATAATAAAAAGGATATAATTTCTTAGTAAAAT; GAAATCAAAGTATTGATCAGGGTAGCAAACTCAAATGCTGACAGGGGCCAGAGGAGATTG; GGGGAANGGAGCATCAGAAATGAGGGCAGCTAGNAGAATGGGCTATTATAAATGTAAGAA; TTGTAGTCTCAGTTAAAGGGGTAGCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002677 unedited; TGGACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTAACATTACTTTCT; GGCATAACAAGATATTTCAAGCTCATCTTGTTCCTACCTTGCCCTTGCTTTGGAATCATC; CATTTTTCCAAGTAGCCTTGGTTCCTTTTAGTGGCAAACTATATTAGACACGAAGATCTG; AGTGCTAGGTATATTCATTTCTGCTGAGGTGTTTTTGTGTCTAAGCCATTTTGGCAGATA; GGATTAGTAAATATATGCATGTGTATACACACACGCACATAAATGCATGTGTATTATCAC; ACACATATATGCATGGAGGCATGTGTATGCAATTATAATACATATAAACGTACATATACA; TGGTTTAGAAATTATGAATTTATACCAATTCTATTCCATTTCCACATGGTTCTTTCTTGC; CTTCCCTCATTTCATATTTGTATATTTGTTTTTCCATAGTGAACATCCTGACTCCCATCA; ACATCAACATGTTTTCTCATTTGCTCAATCATATAATACATCTGAAATAGTTTTATTATT; ACTTGGGCACAATGCAATGGTCCCCCGTTCCTGCCTGTCAACAATTACTGGACCTAATGA; TATGACTAGTTATTTATTTAAAATAAAGGGACTCCTATGTTTACAAAAAGTCTTGTACAA; AAATATTTGTAGCAGCTTTATTCATAGCAGCCGAAAATTAGAATAGCTCAATTGTCTTAA; TAGTAGAATGGATNAACTGTGATATATTCATACCATGAAATAGTACTTGGGTATAAAAAG; AAACAAACTACAGCTGCATGCCCACATGTGGATGTATCACAAAAACATGATGCTGAATTN; AAAAAAGGCAACAGAAAAGATGCATGATGTACAATCCCTTCTATGAGCAGGTAAATAATC; TATTGATAGAACCAACCCTACTTGCTTGGC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002677
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002677.3, NP_002668.1
• RefSeq Size: 3579 bp
• RefSeq ORF: 399 bp
• Locus ID: 5375
• UniProt ID: P02689
• Cytogenetics: 8q21.13
• Domains: lipocalin
• Summary: The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).