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SET (NM_003011) Human Untagged Clone

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SKU
SC118245
SET (untagged)-Human SET nuclear oncogene (SET), transcript variant 2
  $300.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SET
Synonyms 2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; TAF-I; TAF-IBETA
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC118245 sequence for NM_003011 edited (data generated by NextGen Sequencing)
ATGTCGGCGCCGGCGGCCAAAGTCAGTAAAAAGGAGCTCAACTCCAACCACGACGGGGCC
GACGAGACCTCAGAAAAAGAACAGCAAGAAGCGATTGAACACATTGATGAAGTACAAAAT
GAAATAGACAGACTTAATGAACAAGCCAGTGAGGAGATTTTGAAAGTAGAACAGAAATAT
AACAAACTCCGCCAACCATTTTTTCAGAAGAGGTCAGAATTGATCGCCAAAATCCCAAAT
TTTTGGGTAACAACATTTGTCAACCATCCACAAGTGTCTGCACTGCTTGGGGAGGAAGAT
GAAGAGGCACTGCATTATTTGACCAGAGTTGAAGTGACAGAATTTGAAGATATTAAATCA
GGTTACAGAATAGATTTTTATTTTGATGAAAATCCTTACTTTGAAAATAAAGTTCTCTCC
AAAGAATTTCATCTGAATGAGAGTGGTGATCCATCTTCGAAGTCCACCGAAATCAAATGG
AAATCTGGAAAGGATTTGACGAAACGTTCGAGTCAAACGCAGAATAAAGCCAGCAGGAAG
AGGCAGCATGAGGAACCAGAGAGCTTCTTTACCTGGTTTACTGACCATTCTGATGCAGGT
GCTGATGAGTTAGGAGAGGTCATCAAAGATGATATTTGGCCAAACCCATTACAGTACTAC
TTGGTTCCCGATATGGATGATGAAGAAGGAGAAGGAGAAGAAGATGATGATGATGATGAA
GAGGAGGAAGGATTAGAAGATATTGACGAAGAAGGGGATGAGGATGAAGGTGAAGAAGAT
GAAGATGATGATGAAGGGGAGGAAGGAGAGGAGGATGAAGGAGAAGATGACTAA

Clone variation with respect to NM_003011.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_003011 unedited
AAACCAATTCCGCACGAGGGGAGGAGGCGGCCGGACCGAGCGGGCGCCCGCGCGTGTGGC
GTGAGGGGAAGCCGCTTGCCCGCCCCCTTCGCCTTCCCTTCTCTCCCCCTCCCCGCTCCC
CCCCCGACCGCGGAGCAGCACCATGTCGGCGCCGGCGGCCAAAGTCAGTAAAAAGGAGCT
CNATTCCAACCACGACGGGGCCGACGAGACCTCAGAAAAAGAACAGCAAGAAGCGATTGA
ACACATTGATGAAGTACAAAATGAAATAGACAGACTTAATGAACAAGCCAGTGAGGAGAT
TTTGAAAGTAGAACAGAAATATAACAAACTCCGCCAACCATTTTTTCAGAAGAGGTCAGA
ATTGATCGCCAAAATCCCAAATTTTTGGGTAACAACATTTGTCAACCATCCACAAGTGTC
TGCACTGCTTGGGGAGGAAGATGAAGAGGCACTGCATTATTTGACCAGAGTTGAAGTGAC
AGAATTTGAAGATATTAAATCAGGTTACAGAATAGATTTTTATTTTGATGAAAATCCTTA
CTTTGAAAATAAAGTTCTCTCCAAAGAATTTCATCTGAATGAGAGTGGTGATCCATCTTC
GAAGTCCACCGAAATCAAATGGAAATCTGGAAAGGATTTGACGAAACGTTCGAGTCAAAC
GCAGAATAAAGCCAGCAGGAAGAGGCAGCATGAGGAACCAGAGAGCTTCTTTACCTGGTT
TACTGACCATTCTGATGCAGGTGCTGATGAGTTAGGAGAGGTCATCANAGATGATATTTG
GGCCAAACCCATTACAGTACTACTTGGTTCCCCGATATGGATGATGAAGAAGGAGAAGGA
GAAAGAGATGATGATGATGATGA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_003011 unedited
CTAGGACCCGGCCGCATCTAAAGTCGGTTTTTTTTTTTTTTTTTTAAACAAAAGAAGTAG
ACAGATACATGTTGGTAAATGCTAACTGTCCATATTCACATAGAGACACAGTGTACTCTC
TGAGCCCAATATACAGAGAAAGGAGGAAAAAAGCTAGAATTCTATGCACTACTACACAGG
GGCCTAGCACCCTCCAGCTTCCAGCAGAGCGAAGGGAGCAGGTTTTTCTTTTTTCCCACA
GAGCTCGGAGGAGTTGATTCCATACAGTTTTTGTTCAGACAGGAAGGGATAAAAATGAAC
TTCGAACAGAAAGGGGTAGAGACTCTTTTCCCATTGTATTCTGCTCAAGGTATTTCCCCC
CAAATAAATTGAGAACCATGGAGTAGAGAAAAGAGACCTCAAGAACAGGGCGACTGAGCA
CAAGAGGGAAAAAAAAAAAAAAAAAAAAAAAAAGACTGCAACTTGCTCCCAGGGACTGGA
GAAAATTTAAAAAAAGGAAGGTTGGAATCCATCAGGGTTCTATTTAGACATCTTCTCCTT
CATCCTCCTCTACTTCCTACCCTTATAATAATCTTCATCTTCTTAAACTTCATCCTAATA
CCCTTCTTCGAAAATATCTTCTAATCCTTACTCCTCTTAATAATAATAATCATCCTTCCT
CAACTTCTGCTTCTTCATCATGCATATTCGGGAACCCAAGACCACTCGCATGGGTTTGGC
CAAAATCATCTTTGATGACCCGCCCTAACTATCAGCACCTGCATCACAATGGTAGTAAAC
CCAGTAAGAAACTCTCTGGTCCTCAAGCCGACTCTTCCGCTGGCTTATTCTGCGTTTGCT
CGAACGTTCCCCAATCCTTCCAAATTCCTTTGATTCGGCGGACTCAAAAGGACACCACCC
TATCACAGAAACCTCGGAAAACTTATTTCAAGAAGGCATTACAAATAAAACCTCCGCGAC
CGTTTAATTCCAT
Restriction Sites NotI-NotI |
ACCN NM_003011
Insert Size 1480 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_003011.1, NP_003002.1
RefSeq Size 2577 bp
RefSeq ORF 834 bp
Locus ID 6418
UniProt ID Q01105
Cytogenetics 9q34.11
Domains NAP
Protein Families Druggable Genome, Phosphatase, Stem cell - Pluripotency
Summary The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2011
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
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Documents
Resources
"NM_003011" in other vectors (6)
SKU Description Size Price
RC207606 SET (Myc-DDK-tagged)-Human SET nuclear oncogene (SET), transcript variant 2 10 ug
$300.00
RC207606L1 Lenti ORF clone of Human SET nuclear oncogene (SET), transcript variant 2, Myc-DDK-tagged 10 ug
$600.00
RC207606L2 Lenti ORF clone of Human SET nuclear oncogene (SET), transcript variant 2, mGFP tagged 10 ug
$600.00
RC207606L3 Lenti ORF clone of Human SET nuclear oncogene (SET), transcript variant 2, Myc-DDK-tagged 10 ug
$600.00
RC207606L4 Lenti ORF clone of Human SET nuclear oncogene (SET), transcript variant 2, mGFP tagged 10 ug
$600.00
RG207606 SET (tGFP-tagged) - Human SET nuclear oncogene (SET), transcript variant 2 10 ug
$489.00 $500.00

file-alt Citations

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