ESE1 (ELF3) (NM_004433) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | ESE1 |
| Synonyms | EPR-1; ERT; ESE-1; ESX |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_004433 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_004433.3, NP_004424.2 |
| RefSeq Size | 5036 bp |
| RefSeq ORF | 1116 bp |
| Locus ID | 1999 |
| UniProt ID | P78545 |
| Cytogenetics | 1q32.1 |
| Domains | AT_hook, ETS, SAM_PNT |
| Protein Families | Transcription Factors |
| Summary | Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGAAT. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).UniProtKB/Swiss-Prot Function Transcript Variant: This variant represents the shorter transcript (1). Variants 1 and 2 encode the same protein. |
Reviews
Documents
| Product Manuals |
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| SDS |
Resources
"NM_004433" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC200631 | ELF3 (Myc-DDK-tagged)-Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1 | 10 ug |
$457.00
|
|
| RC200631L1 | Lenti ORF clone of Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC200631L2 | Lenti ORF clone of Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1, mGFP tagged | 10 ug |
$757.00
|
|
| RC200631L3 | Lenti ORF clone of Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC200631L4 | Lenti ORF clone of Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1, mGFP tagged | 10 ug |
$757.00
|
|
| RG200631 | ELF3 (tGFP-tagged) - Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1 | 10 ug |
$489.00
$657.00
|
|
Citations
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