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XRCC3 (NM_005432) Human Untagged Clone

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SKU
SC116733
XRCC3 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol XRCC3
Synonyms CMM6
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC116733 sequence for NM_005432 edited (data generated by NextGen Sequencing)
ATGGATTTGGATCTACTGGACCTGAATCCCAGAATTATTGCTGCAATTAAGAAAGCCAAA
CTGAAATCGGTAAAGGAGGTTTTACACTTTTCTGGACCAGACTTGAAGAGACTGACCAAC
CTCTCCAGCCCCGAGGTCTGGCACTTGCTGAGAACGGCCTCCTTACACTTGCGGGGAAGC
AGCATCCTTACAGCACTGCAGCTGCACCAGCAGAAGGAGCGGTTCCCCACGCAGCACCAG
CGCCTGAGCCTGGGCTGCCCGGTGCTGGACGCGCTGCTCCGCGGTGGCCTGCCCCTGGAC
GGCATCACTGAGCTGGCCGGACGCAGCTCGGCAGGGAAGACCCAGCTGGCGCTGCAGCTC
TGCCTGGCTGTGCAGTTCCCGCGGCAGCACGGAGGCCTGGAGGCTGGAGCCGTCTACATC
TGCACGGAAGACGCCTTCCCGCACAAGCGCCTGCAGCAGCTCATGGCCCAGCAGCCGCGG
CTGCGCACTGACGTTCCAGGAGAGCTGCTTCAGAAGCTCCGATTTGGCAGCCAGATCTTC
ATCGAGCACGTGGCCGATGTGGACACCTTGTTGGAGTGTGTGAATAAGAAGGTCCCCGTA
CTGCTGTCTCGGGGCATGGCTCGCCTGGTGGTCATCGACTCGGTGGCAGCCCCATTCCGC
TGTGAATTTGACAGCCAGGCCTCCGCCCCCAGGGCCAGGCATCTGCAGTCCCTGGGGGCC
ACGCTGCGTGAGCTGAGCAGTGCCTTCCAGAGCCCTGTGCTGTGCATCAACCAGGTGACA
GAGGCCATGGAGGAGCAGGGCGCAGCACACGGGCCGCTGGGGTTCTGGGACGAACGTGTT
TCCCCAGCCCTTGGCATAACCTGGGCTAACCAGCTCCTGGTGAGACTGCTGGCTGACCGG
CTCCGCGAGGAAGAGGCTGCCCTCGGCTGCCCAGCCCGGACCCTGCGGGTGCTCTCTGCC
CCCCACCTGCCCCCCTCCTCCTGTTCCTACACGATCAGTGCCGAAGGGGTGCGAGGGACA
CCTGGGACCCAGTCCCACTGA

Clone variation with respect to NM_005432.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_005432 unedited
GGCTTTCCAGGAATTTGTACTACGATCTCACTATAGGGCGGCCGCGAATTCGCACGAGGG
GAGACACTTAAGGGAAATTAAACTGCAGAGTGCAAGAGATGCCTCAGTCAAGTCAGCCAA
AAACACGCGGGTCATCCCCAAGCCCCAGAGAGTGACAGAGCCCCGATGACACGGACACCT
CGGCTGCTGTCACTTCCCTGGTTCGGGCCTCCCACAGGCTTTGAATTGAAGGCGAGTGCC
TCAGAATTTGCATCCATTGTTCTGTCTTTCCTGGGAAGTTATTCATCCTGGTGGCCAGCC
CACCGACAAAATGGATTTGGATCTACTGGACCTGAATCCCAGAATTATTGCTGCAATTAA
GAAAGCCAAACTGAAATCGGTAAAGGAGGTTTTACACTTTTCTGGACCAGACTTGAAGAG
ACTGACCAACCTCTCCAGCCCCGAGGTCTGGCACTTGCTGAGAACGGCCTCCTTACACTT
GCGGGGAAGCAGCATCCTTACAGCACTGCAGCTGCACCAGCAGAAGGAGCGGTTCCCCAC
GCAGCACCAGCGCCTGAGCCTGNGCTGCCCGGTGCTGGACGCGCTGCTCCGCGGTGGCCT
GCCCCTGGACGGCATCACTGAGCTGGCCGGACGCAGCTCGGCAGGGAAGACCCAGCTGGC
GCTGCAGCTCTGCCTGGCTGTGCAGTTCCCGCGGCAGCACGGNAGCCTGGAGGCTGGAGC
CGTCTACATCTGCACGGAAGACGCCTTCCCGCACAAGCGCCTGCAGCAGCTCATGGCCCA
GCAGCCGCGGCTGCGCACTGACGTTTCCAGAGAGCTGCTTCAGGAGCTCCGATTTGGCAG
CCAGATCTTCATCGAGCACGTGGCCGATGTGGACATCCTGCTTGNAGTGTGTGAACAAC
3' Read Nucleotide Sequence
>OriGene 3' read for NM_005432 unedited
CCCGGGGCCCCACCACATCTTTTTCTCCNNCCGGNTTTACTTGANACCGCGGCCGCATTC
TAGATCGAGTTTTTTTTTTTTTTTTTTTTTTGCATCCATTGACATTTATTTGTCAAAGGC
CTGGTCTGTGCCAGGCAGCATGTGGAGGCACTGAGTGGGGGGTGGAGGGGGTTGTACCGT
GGGAATCAAGGGGGTCACCACTGTGCCCATGGGGAGGCCACGCCACTCTGCCTGCTGGGT
GGATATTTCAGCCTGTGCAGCCAGATGTGTTCCCAGGAGGCTCTGCTTTCCAGCCAGATG
TAAGGCCTGGCCACAGTGTGGGACTGGGTCTGCACAGTGTGGGACTGCAGGACAGGGTCC
TGCAGGTGGCCCTGCCAGGAGTCCTGCCATATCCCTACCAGAATACCACCCAGCCAGGCC
AGGGCTGAGCTGGACGCCCAGACCCCCAGGGCCAGGATACACCGGGACCCTCCTTCCTCT
CAACCTCGGATCCTCTTTGCCCAAAACTGTGTTCCCAGGTGGCTGACGAGCCTGTCACGT
GCCAACCCTGCGCTGCCTGCGCTCCTCTGACCGGCTGTGGTGCTGGCACAGGCCACACTA
CTAGAGACAAGGCAAGTCCCCCACCCCCACGCTCTCCTGGACCCTGACACTGGAGGTTGG
TGGGATATGCTTTTTTCCACTTGTACCACACCTGAAGTTTTGTTGGGCACAGTGTGTGCC
CAAGTTGGTGCCCCCCGGGAGCCAAGGACCCACAAGTGGGTGAGGAGAAGCCGCTTGCCT
GAAANCCCATTGTGGCCTGAATGGGGGGGGAATAAAGACTGCCCTTTGTGCACGAAGGGA
GACCCTCCGGGGCACCGTCCCAGGCTTAGGGGGTTTTAAGCCTCAACCCAGGGGGCAGGC
CCAAAACCAACCCCTTTTGGCTTTCATTGGAAAAAAAAAAAGGGCGTTTCCAGGGGATCC
CGTTGGAACCTCCGGCTCCACCCTTGAAAAACCTTTCCCN
Restriction Sites NotI-NotI |
ACCN NM_005432
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_005432.2, NP_005423.1
RefSeq Size 2615 bp
RefSeq ORF 1041 bp
Locus ID 7517
UniProt ID O43542
Cytogenetics 14q32.33
Protein Families Druggable Genome
Protein Pathways Homologous recombination
Summary This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) lacks a segment in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
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Documents
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"NM_005432" in other vectors (6)
SKU Description Size Price
RC200326 XRCC3 (Myc-DDK-tagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2 10 ug
$457.00
RC200326L1 Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC200326L2 Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mGFP tagged 10 ug
$757.00
RC200326L3 Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC200326L4 Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mGFP tagged 10 ug
$757.00
RG200326 XRCC3 (tGFP-tagged) - Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2 10 ug
$489.00 $657.00

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