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TRIM38 (NM_006355) Human Untagged Clone

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SKU
SC116143
TRIM38 (untagged)-Human tripartite motif containing 38 (TRIM38)
  $457.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TRIM38
Synonyms RNF15; RORET
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_006355 edited
GAATTCGGCACGAGGGCGAATATGTAAGTGTCTGAGCAGTGAAGGTTACGGAAAAGGTCC
AGGCTAAGGTTTTCTCAGTGGATATACTTTACACCAAATCTCAGAAGATTCAGAACTTAG
ATGAGTGGGGCCCAGGACAGGAACCCTGGAGCCTTGGAAGGAGGGGAGCCCCATCTCCCC
AGAAGAGCAGTGACCCCAGCAGAGAGGGGCCTGGTGTATCACTGGAGGAAATAGCCTGCC
AAGGAATACACGTCTTCAGAAGAAATTCTGTGTGGCTTCAAGAGACTGATCAAATTGTGA
GAGGAAAACAGCCTACCCGGTCCTCTTTTCTTCAATACAAAATGAGATAATAGGGGTTGG
AAGGAAAACCTTCAAGACCTATGGAAGTCAGTTGCAGCCAGCTCATCACATAGAGGTGCA
GGTGAGGTGTATTTTCATCACGGTGGAAAATTCTGGCTGCTTCATCTCCATCTCTAGAGC
CAATATTGGAGCTTTTCAATAAAAGCTATGGCCTCAACCACCAGCACCAAGAAGATGATG
GAGGAAGCCACCTGCTCCATCTGCCTGAGCCTGATGACGAACCCAGTAAGCATCAACTGT
GGACACAGCTACTGCCACTTGTGTATAACAGACTTCTTTAAAAACCCAAGCCAAAAGCAA
CTGAGGCAGGAGACATTCTGCTGTCCCCAGTGTCGGGCTCCATTTCATATGGATAGCCTC
CGACCCAACAAGCAGCTGGGAAGCCTCATTGAAGCCCTCAAAGAGACGGATCAAGAAATG
TCATGTGAGGAACACGGAGAGCAGTTCCACCTGTTCTGCGAAGACGAGGGGCAGCTCATC
TGCTGGCGCTGTGAGCGGGCACCACAGCACAAAGGGCACACCACAGCTCTTGTTGAAGAC
GTATGCCAGGGCTACAAGGAAAAGCTCCAGAAAGCTGTGACAAAACTGAAGCAACTTGAA
GACAGATGTACGGAGCAGAAGCTGTCCACAGCAATGCGAATAACTAAATGGAAAGAGAAG
GTACAGATTCAGAGACAAAAAATCCGGTCTGACTTTAAGAATCTCCAGTGTTTCCTACAT
GAGGAAGAGAAGTCTTATCTCTGGAGGCTGGAGAAAGAAGAACAACAGACTCTGAGTAGA
CTGAGGGACTATGAGGCTGGTCTGGGGCTGAAGAGCAATGAACTCAAGAGCCACATCCTG
GAACTGGAGGAAAAATGTCAGGGCTCAGCCCAGAAATTGCTGCAGAATGTGAATGACACT
TTGAGCAGGAGTTGGGCTGTGAAGCTGGAAACATCAGAGGCTGTCTCCTTGGAACTTCAT
ACTATGTGCAATGTTTCCAAGCTTTACTTCGATGTGAAGAAAATGTTAAGGAGTCATCAA
GTTAGTGTGACTCTGGATCCAGATACAGCTCATCACGAACTAATTCTCTCTGAGGATCGG
AGACAAGTGACTCGTGGATACACCCAGGAGAATCAGGACACATCTTCCAGGAGATTTACT
GCCTTCCCCTGTGTCTTGGGTTGTGAAGGCTTCACCTCAGGAAGACGTTACTTTGAAGTG
GATGTTGGCGAAGGAACCGGATGGGATTTAGGAGTTTGTATGGAAAATGTGCAGAGGGGC
ACTGGCATGAAGCAAGAGCCTCAGTCTGGATTCTGGACCCTCAGGCTGTGCAAAAAGAAA
GGCTATGTAGCACTTACTTCTCCCCCAACTTCCCTTCATCTGCATGAGCAGCCCCTGCTT
GTGGGAATTTTTCTGGACTATGAGGCCGGAGTTGTATCCTTTTATAACGGGAATACTGGC
TGCCACATCTTTACTTTCCCGAAGGCTTCCTTCTCTGATACTCTCCGGCCCTATTTCCAG
GTTTATCAATATTCTCCTTTGTTTCTGCCTCCCCCAGGTGACTAAGGAAAAGAGCAGAAG
CTCCTTGGTTTAACCAGCACAGAGAAAATAATATAAATCCCATAAGGGCAGACGTTTGGT
CTGTTTTCTTCGCTGTCATTTCCTTAGTAGTTAGACTAGTGCTGAGATTTTAGTGGATAT
ATAATTGATTTATGTTGAATATATGGACTTAGCAACTAAAAATACCACAGATGGTTAACC
TGGACTGGGGCAAAGCAAGATAATAGTGATGATCGTATGTTGCTGTCTCCATCCGTCTTT
AATGGGTCAGGGCTTTGATTTCCAAGGGTCTTCAGGTGATGAGTAGGGGTACCCACAAGT
CAGAAGGTCTGCGTTCTCCTAGTTTGTTTGCTGCCATTTGAACTCATGTAGGGAATGAAA
GAAAGCTGCAATTATCCGCCAACTGCATTTAAAACAAAAAAAAAAAAAAAAAACTCGAC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_006355 unedited
ATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGCGAATATGTAAGTGT
CTGAGCAGTGAAGGTTACGGAAAAGTCCAGGCTAAGGTTTTCTCAGTGGATATACTTTAC
ACCAAATCTCAGAAGATTCAGAACTTAGATGAGTGGGGCCCAGGACAGGAACCCTGGAGC
CTTGGAAGGAGGGGAGCCCCATCTCCCCAGAAGAGCAGTGACCCCAGCAGAGAGGGGCCT
GGTGTATCACTGGAGGAAATAGCCTGCCAAGGAATACACGTCTTCAGAAGAAATTCTGTG
TGGCTTCAAGAGACTGATCAAATTGTGAGAGGAAAACAGCCTACCCGGTCCTCTTTTCTT
CAATACAAAATGAGATAATAGGGGTTGGAAGGAAAACCTTCAAGACCTATGGAAGTCAGT
TGCAGCCAGCTCATCACATAGAGGTGCAGGTGAGGTGTATTTTCATCACGGTGGAAAATT
CTGGCTGCTTCATCTCCATCTCTAGAGCCAATATTGGAGCTTTTCAATAAAAGCTATGGC
CTCAACCACCAGCACCAAGAAGATGATGGAGGAAGCCACCTGCTCCATCTGCCTGAGCCT
GATGACGAACCCAGTAAGCATCAACTGTGGACACAGCTACTGCCACTTGTGTATAACAGA
CTTCTTTAAAAACCCAAGCCAAAAGCAACTGAGGCAGGAGACATTCTGCTGTCCCCAGTG
TCGGGCTCCATTTCATATGGATAGCCTNCGACCCCACAGCAGCTGGGAAGCCTCATTGAA
GCCCTCAAGAGACGGATCAAGATATGTCATGTGAGGAACACNGAGAGCAGTTCCACCTGG
TCTGCGAAGACGAGGGGCAGCTCATCTGCTGGCGCTGTGAGCGGGCACACAGCACAAAGG
GCACACACAG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_006355 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTTTAAATGCAGTTG
GCGGATAATTGCAGCTTTCTTTCATTCCCTACATGAGTTCAAATGGCAGCAAACAAACTA
GGAGAACGCAGACCTTCTGACTTGTGGGTACCCCTACTCATCACCTGAAGACCCTTGGAA
ATCAAAGCCCTGACCCATTAAAGACGGATGGAGACAGCAACATACGATCATCACTATTAT
CTTGCTTTGCCCCAGTCCAGGTTAACCATCTGTGGTATTTTTAGTTGCTAAGTCCATATA
TTCAACATAAATCAATTATATATCCACTAAAATCTCAGCACTAGTCTAACTACTAAGGAA
ATGACAGCGAAGAAAACAGACCAAACGTCTGCCCTTATGGGATTTATATTATTTTCTCTG
TGCTGGTTAAACCAAGGAGCTTCTGCTCTTTTCCTTAGTCACCTGGGGGAGGCAGAAACA
AAGGAGAATATTGATAAACCTGGAAATAGGGCCGGAGAGTATCAGAGAAGGAAGCCTTCG
GGAAAGTAAAGATGTGGCAGCCAGTATTCCCGTTATAAAAGGATACAACTCCGGCCTCAT
AGTCCAGAAAAATTCCCACAAGCAGGGGCTGCTCATGCAGATGAAGGGAAAGTGGNGGAG
AAGTAAGTGCTACATAGCCCTTTCTTTTTTGCACAGCCTGGAGGTCCAGAATCCAGACTG
AGGCTCTTGCTTCATGCCAGTGCCCCTCTGCACATTTCCATACAAACTNCTAAATCCCAT
NCGGTTCCTTCGCCACATTCACTTCAAAGTACGTCTTCCTGAGGTGAAGCCTCACCACCC
ACGACACAGGGGAGGCAGTAAATCTCTGGAAGAGTGTCTGATCTCCTGGTTGATTCAGAG
TCACTGNCTCGATCTANANGAATTATTCGTGAGAGCTGATCTGATCCAGACCCACCTACT
GAGACTNCTACATTNTCTCCACTGAGTAG
Restriction Sites NotI-NotI |
ACCN NM_006355
Insert Size 2290 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_006355.2, NP_006346.1
RefSeq Size 3286 bp
RefSeq ORF 1398 bp
Locus ID 10475
UniProt ID O00635
Cytogenetics 6p22.2
Domains PRY, RING, SPRY, zf-B_box
Protein Families Druggable Genome
Summary This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. provided by RefSeq, Jul 2012
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Documents
Resources
"NM_006355" in other vectors (6)
SKU Description Size Price
RC201944 TRIM38 (Myc-DDK-tagged)-Human tripartite motif containing 38 (TRIM38) 10 ug
$457.00
RC201944L1 Lenti ORF clone of Human tripartite motif containing 38 (TRIM38), Myc-DDK-tagged 10 ug
$757.00
RC201944L2 Lenti ORF clone of Human tripartite motif containing 38 (TRIM38), mGFP tagged 10 ug
$757.00
RC201944L3 Lenti ORF clone of Human tripartite motif containing 38 (TRIM38), Myc-DDK-tagged 10 ug
$757.00
RC201944L4 Lenti ORF clone of Human tripartite motif containing 38 (TRIM38), mGFP tagged 10 ug
$757.00
RG201944 TRIM38 (tGFP-tagged) - Human tripartite motif containing 38 (TRIM38) 10 ug
$657.00

file-alt Citations

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages
Zhao, Wang, Zhang et al
J. Immunol. (2012) 188 (6), 2567-74 DOI: 10.4049/jimmunol.1103255
Cited by 127
AI Summary: OriGene contributed to this study by providing the Flag-tagged TRIM38 (NM_006355) expression plasmid, which was used to investigate the regulatory role of TRIM38 in TLR-mediated immune responses.
Snippet: Their respective HRP-conjugated secondary Abs were purchased from Santa Cruz Biotechnology. Sequences, plasmid constructs, and transfection. Flag-tagged TRIM38 (NM_006355) expression plasmid was purchased from OriGene (Rockville, MD).
Showing 1-2 of 2 papers.
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