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LYAR (NM_017816) Human Untagged Clone

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SKU
SC113969
LYAR (untagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1
  $457.00
4 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol LYAR
Synonyms ZC2HC2; ZLYAR
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_017816, the custom clone sequence may differ by one or more nucleotides


ATGGTATTTTTTACATGCAATGCATGTGGTGAATCAGTGAAGAAAATACAAGTGGAAAAGCATGTGTCTG
TTTGCAGAAACTGTGAATGCCTTTCTTGCATTGACTGCGGTAAAGATTTCTGGGGCGATGACTATAAAAA
CCACGTGAAATGCATAAGTGAAGATCAGAAGTATGGTGGCAAAGGCTATGAAGGTAAAACCCACAAAGGC
GACATCAAACAGCAGGCGTGGATTCAGAAAATTAGTGAATTAATAAAGAGACCCAATGTCAGCCCCAAAG
TGAGAGAACTTTTAGAGCAAATTAGTGCTTTTGACAACGTTCCCAGGAAAAAGGCAAAATTTCAGAATTG
GATGAAGAACAGTTTAAAAGTTCATAATGAATCCATTCTGGACCAGGTGTGGAATATCTTTTCTGAAGCT
TCCAACAGCGAACCAGTCAATAAGGAACAGGATCAACGGCCACTCCACCCAGTGGCAAATCCACATGCAG
AAATCTCCACCAAGGTTCCAGCCTCCAAAGTGAAAGACGCCGTGGAACAGCAAGGGGAGGTGAAGAAGAA
TAAAAGAGAAAGAAAGGAAGAACGGCAGAAGAAAAGGAAAAGAGAAAAGAAAGAACTAAAGTTAGAAAAC
CACCAGGAAAACTCAAGGAATCAGAAGCCTAAGAAGCGCAAAAAGGGACAGGAGGCTGACCTTGAGGCTG
GTGGGGAGGAAGTCCCTGAGGCCAATGGCTCTGCAGGGAAGAGGAGCAAGAAGAAGAAGCAGCGCAAGGA
CAGCGCCAGTGAGGAAGAGGCACGCGTGGGCGCAGGGAAGAGGAAGCGGAGGCACTCGGAAGTTGAAACA
GATTCTAAGAAGAAAAAGATGAAGCTCCCAGAGCATCCTGAGGGCGGAGAACCAGAAGACGATGAGGCTC
CTGCAAAAGGTAAATTCAACTGGAAGGGAACTATTAAAGCAATTCTGAAACAGGCCCCAGACAATGAAAT
AACCATCAAAAAGCTAAGGAAAAAGGTTTTAGCTCAGTACTACACAGTGACAGATGAGCATCACAGATCC
GAAGAGGAACTCCTGGTCATCTTTAACAAGAAAATCAGCAAGAACCCTACCTTTAAGTTATTAAAGGACA
AAGTCAAGCTTGTGAAATGA

5' Read Nucleotide Sequence
>OriGene 5' read for NM_017816 unedited
ACTATAGGGGGCGGCCGCGTAATTCGGCACGAGGCCGCGCCCGAGCGGACTGCGGGGCGC
CCCTGCGGCCCGGGCCCGCCGCGCGGACCAGCCCCAACTGAGCGGGAGCGAAAGCGGCGG
CGGCCTCCGGCTCAGACGCAAAGTTCGCTGCCTTCCATTGGAGTGACTGAATTTCTACAT
GACGGCTTTTTGACAAGACTTAAAACCTGTCTTGGATAGAGAATATTTAGCCATTTACCT
AAAAATGGTATTTTTTACATGCAATGCATGTGGTGAATCAGTGAAGAAAATACAAGTGGA
AAAGCATGTGTCTGTTTGCAGAAACTGTGAATGCCTTTCTTGCATTGACTGCGGTAAAGA
TTTCTGGGGCGATGACTATAAAAACCACGTGAAATGCATAAGTGAAGATCAGAAGTATGG
TGGCAAAGGCTATGAAGGTAAAACCCACAAAGGCGACATCAAACAGCAGGCGTGGATTCA
GAAAATTAGTGAATTAATAAAGAGACCCAATGTCAGCCCCAAAGTGAGAGAACTTTTAGA
GCAAATTAGTGCTTTTGACAACGTTCCCAGGAAAAAGGCAAAATTTCATAATTGGATGAA
GAACAGTTTAAAAGTTCATAATGAATCCATTCTGGACCAGGTGTGGAATATCTTTTCTGA
AGCTTCCAACAGCGAACCAGTCAATAATGAACAGGATCAACGGCCACTTCACCCATCGGC
AAATCCACATGCAGAAAATCTCCACCAAGTTTCCAGCCTCCAAAGTGAAAGACGCCCTGG
TACAGCNAGGGGATGGTGAAGATAATTAAACCATAATGATGGGAGTACCGGCCNAAGAAA
GGAAAAGAGAAAAGAAAGAACCTAAGTTTGTAAACCCCCAGCAAAACTCTAGGGATCCGA
GCT
Restriction Sites NotI-NotI |
ACCN NM_017816
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_017816.1, NP_060286.1
RefSeq Size 1598 bp
RefSeq ORF 1140 bp
Locus ID 55646
UniProt ID Q9NX58
Cytogenetics 4p16.3
Summary Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227). Also acts at the level of transcription regulation. Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918). In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580). Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918). Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells (By similarity). Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (By similarity).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
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Documents
Resources
"NM_017816" in other vectors (7)
SKU Description Size Price
RC201908 LYAR (Myc-DDK-tagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 10 ug
$457.00
RC201908L1 Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC201908L2 Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, mGFP tagged 10 ug
$757.00
RC201908L3 Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC201908L4 Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, mGFP tagged 10 ug
$757.00
RG201908 LYAR (tGFP-tagged) - Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 10 ug
$657.00
SC322377 LYAR (untagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 10 ug
$457.00

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