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FBXL15 (NM_024326) Human Untagged Clone

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SKU
SC112212
FBXL15 (untagged)-Human F-box and leucine-rich repeat protein 15 (FBXL15)
  $300.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol FBXL15
Synonyms Fbl15; FBXO37; JET; PSD
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC112212 sequence for NM_024326 edited (data generated by NextGen Sequencing)
ATGGAGCCACCGATGGAGCCGTCCGGAGGGGAGCAAGAGCCCGGAGCCGTCAGGTTCCTG
GACCTGCCCTGGGAAGACGTGCTGCTCCCACACGTCCTGAACCGGGTCCCGCTGCGCCAG
CTGCTCCGGCTGCAGCGCGTTAGCCGGGCCTTCCGGTCGCTGGTGCAGCTTCACCTGGCC
GGGCTGCGTCGCTTCGATGCCGCGCAGGTGGGTCCGCAGATCCCGCGGGCCGCATTGGCC
CGGCTGCTGCGGGATGCCGAGGGGCTGCAGGAGCTGGCACTGGCGCCGTGTCACGAATGG
CTGTCAGACGAGGACCTGGTGCCGGTGCTGGCGCGGAATCCGCAGCTGCGGAGTGTGGCG
TTGGGCGGCTGCGGGCAACTGAGTCGCCGGGCGCTTGGGGCTTTGGCCGAGGGCTGCCCA
CGCCTGCAGCGCCTGTCGCTCGCGCACTGTGACTGGGTGGACGGGCTGGCGCTGCGCGGC
CTCGCTGATCGCTGCCCGGCCCTGGAGGAGCTGGATCTCACCGCCTGCCGCCAGCTCAAG
GACGAGGCCATCGTGTACCTGGCGCAGAGGCGCGGCGCTGGTCTCCGCAGCCTCTCTCTG
GCCGTCAACGCCAACGTGGGGGACGCCGCGGTTCAAGAGTTGGCTCGGAACTGCCCAGAA
CTCCACCACCTTGACCTCACCGGCTGCCTCCGCGTCGGAAGCGACGGTGTCAGGACATTG
GCCGAGTACTGCCCCGTGCTGCGTTCGCTGCGGGTGCGGCACTGCCACCATGTGGCGGAG
TCCAGCCTGAGCCGCTTGCGGAAGCGCGGCGTGGACATCGACGTGGAGCCGCCGCTGCAC
CAGGCCCTGGTGCTGCTGCAGGATATGGCGGGCTTCGCACCTTTTGTCAACCTGCAGGTC
TGA

Clone variation with respect to NM_024326.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_024326 unedited
ATACGACTCTACTATAGGCGGCCGCGAATTCGGCACGAGGGCCGATGGAGCCACCGATGG
AGCCGTCCGGAGGGGAGCAAGAGCCCGGAGCCGTCAGGTTCCTGGACCTGCCCTGGGAAG
ACGTGCTGCTCCCACACGTCCTGAACCGGGTCCCGCTGCGCCAGCTGCTCCGGCTGCAGC
GCGTTAGCCGGGCCTTCCGGTCGCTGGTGCAGCTTCACCTGGCCGGGCTGCGTCGCTTCG
ATGCCGCGCAGGTGGGTCCGCAGATCCCGCGGGCCGCATTGGCCCGGCTGCTGCGGGATG
CCGAGGGGCTGCAGGAGCTGGCACTGGCGCCGTGTCACGAATGGCTGTCAGACGAGGACC
TGGTGCCGGTGCTGGCGCGGAATCCGCAGCTGCGGAGTGTGGCGTTGGGCGGCTGCGGGC
AACTGAGTCGCCGGGCGCTTGGGGCTTTGGCCGAGGGCTGCCCACGCCTGCAGCGCCTGT
CGCTCGCGCACTGTGACTGGGTGGACGGGCTGGCGCTGCGCGGCCTCGCTGATCGCTGCC
CGGCCCTGGAGGAGCTGGATCTCACCGCCTGCCGCCAGCTCAAGGACGAGGCCATCGTGT
ACCTGGCGCAGAGGCGCGGCGCTGGTCTCCGCAGCCTCTCTCTGGCCGTCAACGCCACGT
GGGGGACGCCGCGGTTCAAGAGTTGCCTCGGAACTGCCCCAGACTCCACCCACTTGACCT
CACCGGCTGCCTTCGCCGTGGAAGCGACGGNGTCAGGACATTGGNCCGAATACTGCCCCC
GTGCTGGGTTTCCCTGCGGGNGGCGGGACTGGCACCATGTGGGCGGAATCCAACCTGGAC
CGCTTGCGGAAACCGCGGCGTGGAACTTAACATGGAGCCCGCCGTTGACCACAGCCCTGG
TGCTGCTGCAAGAAATTGGCGGGCTTCCCACCCTT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_024326 unedited
GGACCGCGGCCGCATCTATATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGGTAA
AAAACTCTTTATTTGAAGCTCCAGGGGGGGGCAAGGCACTGGCCTCTCACCAAAGAGTCC
TCACAGTTCAATTTCCCTACAGCTCAATGTCAAGCCCCAACCACACAGTCCAACTGTGCT
CCGATTGGCAAGCGGGTCAAACCTGCAAGTTGACAAAAGGGGCGAATCCCGCCATATTCT
GCAGCAGCACCAAGGCCTGGTGCAGCGGCGGCTCCACGTCGATGTCCACGCCGCGCTTCC
GCAAGCGGGTCAAGCTGGACTCCGCCACATGGTGGCAGTGCCGCACCCGCAGCGAACGCA
GCACGGGGCAGTACTCGGCCAATGTCCTGACACCGTCGCTTTCGACGCGGAAGCAGCCGG
TGAAGTCAAGGTGGTGGAGTTCTGGGCAGTTCCGAACCAACTCTTGAACCGCGGCGTCCC
CCACGTTGGCGTTGACGGCCAAAGAGAGGCTGCGGAGACCAACGCCGCGCCTCTGCGCCA
GGTACACGATGGCCTCGTTCTTGAACTGGCGGCAGGCGGAGAGATCCAATTTCTCCAGGG
CCGGGCAGCGATCATCGAAGCCCCGCATTGCCCATCCCGTTCACCCATTTACAGTGCGCG
AGCGACAAGCGCTTCAAGCGTGGGGAACNCCTTGTCCAAACCCCCATACGCCCGGGAATT
ATTTGCCCCCATCCGCGCCAAGCCACACTTCGCAAGTTGTGGAATTCGGGCCATCACCAG
GACCAAGTTCCTATTCTGAAAATCCTTTTGTGACACAGGGGCCATTGCCAGCTTCTGCAT
CCCCTTTGTTTTCCTCACTAATCCTGGCCAATTGGGGCCCGGGGATCTTGGGACCACCTG
CGCGGTTTTTAACCTACCCATCCCGTCAAGTGTATCCGTCCCATAACCGGAAGGGCTGCT
TAATCTCTCATCCGGATCACTCGCCCCATGTGCCCGGTCTATACGCTGTGAACATTCTTC
TT
Restriction Sites NotI-NotI |
ACCN NM_024326
Insert Size 1110 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_024326.2, NP_077302.2
RefSeq Size 2359 bp
RefSeq ORF 903 bp
Locus ID 79176
UniProt ID Q9H469
Cytogenetics 10q24.32
Domains F-box, LRR_CC
Protein Families Druggable Genome
Summary Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.UniProtKB/Swiss-Prot Function
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"NM_024326" in other vectors (6)
SKU Description Size Price
RC206363 FBXL15 (Myc-DDK-tagged)-Human F-box and leucine-rich repeat protein 15 (FBXL15) 10 ug
$289.00 $300.00
RC206363L1 Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), Myc-DDK-tagged 10 ug
$600.00
RC206363L2 Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), mGFP tagged 10 ug
$600.00
RC206363L3 Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), Myc-DDK-tagged 10 ug
$600.00
RC206363L4 Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), mGFP tagged 10 ug
$600.00
RG206363 FBXL15 (tGFP-tagged) - Human F-box and leucine-rich repeat protein 15 (FBXL15) 10 ug
$500.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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