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TRIB2 (NM_021643) Human Untagged Clone

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SKU
SC111247
TRIB2 (untagged)-Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1
  $457.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TRIB2
Synonyms C5FW; GS3955; TRB2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF sequence for NM_021643 edited
ATGAACATACACAGGTCTACCCCCATCACAATAGCGAGATATGGGAGATCGCGGAACAAA
ACCCAGGATTTCGAAGAGTTGTCGTCTATAAGGTCCGCGGAGCCCAGCCAGAGTTTCAGC
CCGAACCTCGGCTCCCCGAGCCCGCCCGAGACTCCGAACTTGTCGCATTGCGTTTCTTGT
ATCGGGAAATACTTATTGTTGGAACCTCTGGAGGGAGACCACGTTTTTCGTGCCGTGCAT
CTGCACAGCGGAGAGGAGCTGGTGTGCAAGGTGTTTGATATCAGCTGCTACCAGGAATCC
CTGGCACCGTGCTTTTGCCTGTCTGCTCATAGTAACATCAACCAAATCACTGAAATTATC
CTGGGTGAGACCAAAGCCTATGTGTTCTTTGAGCGAAGCTATGGGGACATGCATTCCTTC
GTCCGCACCTGCAAGAAGCTGAGAGAGGAGGAGGCAGCCAGACTGTTCTACCAGATTGCC
TCGGCAGTGGCCCACTGCCATGACGGGGGGCTGGTGCTGCGGGACCTCAAGCTGCGGAAA
TTCATCTTTAAGGACGAAGAGAGGACTCGGGTCAAGCTGGAAAGCCTGGAAGACGCCTAC
ATTCTGCGGGGAGATGATGATTCCCTCTCCGACAAGCATGGCTGCCCGGCTTACGTAAGC
CCAGAGATCTTGAACACCAGTGGCAGCTACTCGGGCAAAGCAGCCGACGTGTGGAGCCTG
GGGGTGATGCTGTACACCATGTTGGTGGGGCGGTACCCTTTCCATGACATTGAACCCAGC
TCCCTCTTCAGCAAGATCCGGCGTGGCCAGTTCAACATTCCAGAGACTCTGTCGCCCAAG
GCCAAGTGCCTCATCCGAAGCATTCTGCGTCGGGAGCCCTCAGAGCGGCTGACCTCGCAG
GAAATTCTGGACCATCCTTGGTTTTCTACAGATTTTAGCGTCTCGAATTCAGCATATGGT
GCTAAGGAAGTGTCTGACCAGCTGGTGCCGGACGTCAACATGGAAGAGAACTTGGACCCT
TTCTTTAACTGA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_021643 unedited
NTGTCAACATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCGGGGTGA
TTGCAAATTATTCCAGGACGAGATCCAGTTCTCCAGCGGGAAAGGGGCAAAGGAACGCCG
CGCGTTGGAAGGGCCAGGGACGCAGCTCCCCTTGCAGCGCCCGCAGGACCCCCGCAAGCT
CGTGCCGGCGAAATCGGAGACCGCCGATCTGTCCTCGTTCTCTCCTGCACGTCTGGCTGC
ATTCGGAGGAAGACCTGGGGCGCGAGCGAGCGGCGACAGCATGAGCCTGTGCTGACCTCC
GCGCGGCGGGCCGAGCCCAGGGCTTTGTCGCGGTACCTGCGCCCAGCCCGCGCCGCAACT
CTGTGCCCAGCTTTTGCAATCTTTTGTTGGCAGCGCTGACCGCACCAAGTTAAATGCTCC
CTTGCAATTTTTCTTTTTTTTGTTTGTTTGTTTAATTTTTGGAGAGCTCGCGATCTTGGA
AAAGCCTCAGACGCCATCTACAGTTAAAACGTAGGTAACTGCCCTCTCCCGCACCCCCCC
CTTACACGCCCCCCACCCTTTCCACCAAAAAAAGGGGGTGCAGCGCGGATTCTGGCTGCC
GTGCGTCGCCAGCCGGTAGACCCGTGCTTGTTTCCTTTCTCTTTTTGTTTGGCTTCTAAC
GCGTTGGGACTGAGTCGCCGCCGTGAGCTCCCCGAAGACTGCACAAACTACCGCGGGCTC
CTCCGCCCCGTCTGCGATTCGGAAGCCGGCCTGGGGGNTCGCGTCGGGAGCCCTGGCGCT
GCAGCTCCGCACCTTAGCAGCCCGGGTACTCATCCAGATCCACGCCGGGACACCACACCA
GAGTACTAAAAGTGCGGCGATTCTGCACATCGNCGACTGCTTTGGGGTAACAAAAGACCC
GAGTTGCCTGN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_021643 unedited
NNTTCCTTGNCCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTAGTTAAAT
ACGCACAATTTTATTGATTGAAGAGATTAGGACAAAAACATTAAACCAAATACAGGACAA
AGCACCAGAGGCCATAGATCCCCACCATGCATGTCACCAACCTCTCCTCCTCCAAGGTAC
TTAAAAAATAGGGGAGAGGGGAAAAAAAGGTCCTTCTTGACACAGCACCATCTTCAGAAT
GTTAAAAAAAAAAAAAAACCTTCTCTCCTTTCTATCTTCCATTAGCAAAATAGAATCAAG
GGCAAATCCATGGCCGCCTTGTCTCCTGGTTACGAAGGGTGAAGCCGCCCTCCTGGGAAC
GTGAGGACAGGGCTCCTGCTGCGCAGGCATAAAGCATCCAAGAGTCTGCACATACATGCC
ACACACTATTATGAAGCACAGATTCAAGTAACATTTACATACTAGAGTCCACGTGTCACC
TACCCAAAAACAGGACCATTTCACAAAACATATACAGGCAGTCAAATCCGAACAAGTGAG
GTACTGGGAACACAAATATTTATGCCAAAAGAGTTCTGTATCATACAGCAATAGAAAAGC
CGTAATAAAAAACATTTTGCCACTCGAAATCAAATAAAGCTATCTAGAAAAGCCAAGTAA
AAGGTTATTTCAGAGACAGAAATACTCAAACAAGGAAAAAGAATTATAAATGTTAACTAC
AGCATGTAATATGTCATCCCAAGTCACCCCGTAATTGGAGTACTGGCTAANTACATCACA
ATGTGACATTTTCCTTACTAAATAGAAGAGTTCTTGAAATACAAAAGTGCGTATTGGGAT
GAGAGCTGGTTTTATTTATATCATATAGCTTCAGCTAATTATCCTTCCGCTTGCCCTACT
GAGGNTTTTGCCAAACAGAGGGCCTTACAGCC
Restriction Sites NotI-NotI |
ACCN NM_021643
Insert Size 4230 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_021643.1, NP_067675.1
RefSeq Size 4221 bp
RefSeq ORF 1032 bp
Locus ID 28951
UniProt ID Q92519
Cytogenetics 2p24.3
Domains pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase
Summary This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Mar 2009
Transcript Variant: This variant (1) encodes a functional protein.
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Documents
Resources
"NM_021643" in other vectors (6)
SKU Description Size Price
RC201210 TRIB2 (Myc-DDK-tagged)-Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1 10 ug
$457.00
RC201210L1 Lenti ORF clone of Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC201210L2 Lenti ORF clone of Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1, mGFP tagged 10 ug
$757.00
RC201210L3 Lenti ORF clone of Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC201210L4 Lenti ORF clone of Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1, mGFP tagged 10 ug
$757.00
RG201210 TRIB2 (tGFP-tagged) - Human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1 10 ug
$489.00 $657.00

file-alt Citations

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