Stanniocalcin 1 (STC1) (NM_003155) Human Untagged Clone

SKU SC111027

STC1 (untagged)-Human stanniocalcin 1 (STC1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Stanniocalcin 1
• Synonyms: STC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003155, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCTCCAAAACTCAGCAGTGCTTCTGGTGCTGGTGATCAGTGCTTCTGCAACCCATGAGGCGGAGCAGA; ATGACTCTGTGAGCCCCAGGAAATCCCGAGTGGCGGCTCAAAACTCAGCTGAAGTGGTTCGTTGCCTCAA; CAGTGCTCTACAGGTCGGCTGCGGGGCTTTTGCATGCCTGGAAAACTCCACCTGTGACACAGATGGGATG; TATGACATCTGTAAATCCTTCTTGTACAGCGCTGCTAAATTTGACACTCAGGGAAAAGCATTCGTCAAAG; AGAGCTTAAAATGCATCGCCAACGGGGTCACCTCCAAGGTCTTCCTCGCCATTCGGAGGTGCTCCACTTT; CCAAAGGATGATTGCTGAGGTGCAGGAAGAGTGCTACAGCAAGCTGAATGTGTGCAGCATCGCCAAGCGG; AACCCTGAAGCCATCACTGAGGTCGTCCAGCTGCCCAATCACTTCTCCAACAGATACTATAACAGACTTG; TCCGAAGCCTGCTGGAATGTGATGAAGACACAGTCAGCACAATCAGAGACAGCCTGATGGAGAAAATTGG; GCCTAACATGGCCAGCCTCTTCCACATCCTGCAGACAGACCACTGTGCCCAAACACACCCACGAGCTGAC; TTCAACAGGAGACGCACCAATGAGCCGCAGAAGCTGAAAGTCCTCCTCAGGAACCTCCGAGGTGAGGAGG; ACTCTCCCTCCCACATCAAACGCACATCCCATGAGAGTGCATAA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003155 unedited; GAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCAAGAAGCAGCGACTGC; AGCAGCAGCAGCAGCAGCGGCGGTGGCAGCAGCAGCAGCAGCGGCGGCAGCAGCAGCAGC; AGCGGAGGCACCGGTGGCAGCAGCAGCATCACCAGCAACAACAACAAAAAAAAATCCTCA; TCAAATCCTCACCTAAGCTTTCAGTGTATCCAGATCCACATCTTCACTCAAGCCAGGAGA; GGGAAAGAGGAAAGGGGGGCAGGAAAAAAAAAAAACCCAACAACTTAGCGGAAACTTCTC; AGAGAATGCTCCAAAACTCAGCAGTGCTTCTGGTGCTGGTGATCAGTGCTTCTGCAACCC; ATGAGGCGGAGCAGAATGACTCTGTGAGCCCCAGGAAATCCCGAGTGGCGGCTCAAAACT; CAGCTGAAGTGGTTCGTTGCCTCAACAGTGCTCTACAGGTCGGCTGCGGGGCTTTTGCAT; GCCTGGAAAACTCCACCTGTGACACAGATGGGATGTATGACATCTGTAAATCCTTCTTGT; ACAGCGCTGCTAAATTTGACACTCAGGGAAAAGCATTCGTCAAAGAGAGCTTAAAATGCA; TCGCCAACGGGGTCACCTNCAAGGTCTTCCTCGCCTTCGGAGGTGCTCCACTTTCCAAAG; GATGATTGCTGAGGTGCNGAANGAGTGCTACAGCAAGCTGAATGTGTGCAGCATCGCCAA; GCGGACCCTGAAGCCTCACTGGAGGTCGTCCAGCTGCCCATCACTTNCTCAACAGATACT; ATACAGACTTGTCCCGAGCCTGCTGGAATGTGATGAAAACACCGTCAGCCAATCAGAGAC; AGCCTGATGAGAAAATGGGCCTACATGGGCAGNCTCTTCCAATNCTGCAAAAAACCACTG; GGCCAAACACACCCGNAGCTGACTTACAGGAGACCACCATGACCGCAGAACTGAAGTCCT; CCTAGAACCCCGGGGGGGAGGGGCCTC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003155 unedited; NAGCTTCNGTNNGNAGNGGCNGTGCGGTGCGGGACNACNANNGAGCGCTTCGCGCGCTAC; AGGNNACGAAAATTTTATGAGAAGTCTATTAAGGCTGAAACACTCCAGGGTTATTTATAC; TCTCTCAGCCCCAAGTCCCCCGGACTAAAGACCTAAAGGCTGATTGACTCATTCCTGATT; GTATTTAATGGAAAGTCTCCCACCCCATCATCATTAGCCAGAGAATCATGCGTCGGTGAA; AGGGGACGAGNATTTTTCTGCCACTTCCTAATGTCTCGTAGGCCTTATCACACTGTAAGT; GGTCCAAGCCCATAGGGACCCCCTTTTTGGTTCCTGGCCTTTCCAGCCGGATGTGACAGA; GATCTTTCAGTATAGGTCTAAGCCAAGAGTTGCCTCTGGGCTGAGGTGGGCTGGCCGATT; AACATCTTACCTGGGGTCCTTTCCATAGGCCTGCCGGTCCCCCCTGCCTCATACAGGCCC; CTCCTAACTCTTGGGGTTCGCTTCACCCTCCTTCTACTCCCTCCGCTTTCCTCAGGGCCA; TAGGGCGCCTCCCTGCGCTCCTTCTGGTCGTGCCGCCCTCCTCTCCTCCTCCGTTCGCCT; TTCCTCGCCCGCGTCCCCCCCCGACCGCCCCCGCCGTCGCGCTTCCCTTTCCTGCTCTCT; CCCCCCCCCCCCGCTTCTGCGCCCTCTGTTCCCGTCCCCTCCGTTTTCCCCTTCTCCTCG; TCGACCTCCTCTACCTTTTCTATTCCTTTGGGCCTCCGCCCCCCTCGTCCCCCCCCCGTT; CCGTCCCTGACCACGACCCCGTTCTGCCGCCCCGCTTCCTCCGGCCCTCCCCTCCAACTG; CTGTTTCTTCCGTCTCTATCGCCGCCGGCCCCCCCCGTCTGTGTTGTGTTGCGATGTGGC; GGTTGCCCTGCGTTCTTCCCGTCGCGGCATGTGCGCGCCCCAACAAACCAACTATAAC;
• Restriction Sites: NotI-NotI
• ACCN: NM_003155
• Insert Size: 2660 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003155.2, NP_003146.1
• RefSeq Size: 3897 bp
• RefSeq ORF: 744 bp
• Locus ID: 6781
• UniProt ID: P52823
• Cytogenetics: 8p21.2
• Domains: Stanniocalcin
• Protein Families: Druggable Genome, Secreted Protein
• Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]