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RAD51C (NM_058216) Human Untagged Clone

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SKU
SC109703
RAD51C (untagged)-Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol RAD51C
Synonyms BROVCA3; FANCO; R51H3; RAD51L2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC109703 sequence for NM_058216 edited (data generated by NextGen Sequencing)
ATGCGCGGGAAGACGTTCCGCTTTGAAATGCAGCGGGATTTGGTGAGTTTCCCGCTGTCT
CCAGCGGTGCGGGTGAAGCTGGTGTCTGCGGGGTTCCAGACTGCTGAGGAACTCCTAGAG
GTGAAACCCTCCGAGCTTAGCAAAGAAGTTGGGATATCTAAAGCAGAAGCCTTAGAAACT
CTGCAAATTATCAGAAGAGAATGTCTCACAAATAAACCAAGATATGCTGGTACATCTGAG
TCACACAAGAAGTGTACAGCACTGGAACTTCTTGAGCAGGAGCATACCCAGGGCTTCATA
ATCACCTTCTGTTCAGCACTAGATGATATTCTTGGGGGTGGAGTGCCCTTAATGAAAACA
ACAGAAATTTGTGGTGCACCAGGTGTTGGAAAAACACAATTATGTATGCAGTTGGCAGTA
GATGTGCAGATACCAGAATGTTTTGGAGGAGTGGCAGGTGAAGCAGTTTTTATTGATACA
GAGGGAAGTTTTATGGTTGATAGAGTGGTAGACCTTGCTACTGCCTGCATTCAGCACCTT
CAGCTTATAGCAGAAAAACACAAGGGAGAGGAACACCGAAAAGCTTTGGAGGATTTCACT
CTTGATAATATTCTTTCTCATATTTATTATTTTCGCTGTCGTGACTACACAGAGTTACTG
GCACAAGTTTATCTTCTTCCAGATTTCCTTTCAGAACACTCAAAGGTTCGACTAGTGATA
GTGGATGGTATTGCTTTTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGG
TTATTAAATGGCCTAGCCCAGCAAATGATCAGCCTTGCAAATAATCACAGATTAGCTGTA
ATTTTAACCAATCAGATGACAACAAAGATTGATAGAAATCAGGCCTTGCTTGTTCCTGCA
TTAGGGGAAAGTTGGGGACATGCTGCTACAATACGGCTAATCTTTCATTGGGACCGAAAG
CAAAGGTTGGCAACATTGTACAAGTCACCCAGCCAGAAGGAATGCACAGTACTGTTTCAA
ATCAAACCTCAGGGATTTAGAGATACTGTTGTTACTTCTGCATGTTCATTGCAAACAGAA
GGTTCCTTGAGCACCCGGAAACGGTCACGAGACCCAGAGGAAGAATTATAA

Clone variation with respect to NM_058216.1
5' Read Nucleotide Sequence
>OriGene 5' read for NM_058216 unedited
NGGGTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCAGCGAGG
GCGTGCGGAGTTTGGCTGCTCCGGGGTTAGCAGGTGAGCCTGCGATGCGCGGGAAGACGT
TCCGCTTTGAAATGCAGCGGGATTTGGTGAGTTTCCCGCTGTCTCCAGCGGTGCGGGTGA
AGCTGGTGTCTGCGGGGTTCCAGACTGCTGAGGAACTCCTAGAGGTGAAACCCTCCGAGC
TTAGCAAAGAAGTTGGGATATCTAAAGCAGAAGCCTTAGAAACTCTGCAAATTATCAGAA
GAGAATGTCTCACAAATAAACCAAGATATGCTGGTACATCTGAGTCACACAAGAAGTGTA
CAGCACTGGAACTTCTTGAGCAGGAGCATACCCAGGGCTTCATAATCACCTTCTGTTCAG
CACTAGATGATATTCTTGGGGGTGGAGTGCCCTTAATGAAAACAACAGAAATTTGTGGTG
CACCAGGTGTTGGAAAAACACAATTATGTATGCAGTTGGCAGTAGATGTGCAGATACCAG
AATGTTTTGGAGGAGTGGCAGGTGAAGCAGTTTTTATTGATACAGAGGGAAGTTTTATGG
TTGATAGAGTGGTAGACCTTGCTACTGCCTGCATTCAGCACCTTCAGCTTATAGCAGAAA
AACACAAGGGAGAGGAACACCGAAAAGCTTTGGAGGATTTCACTCTTGATAATATTCTTT
CTCATATTTATTATTTTCGCTGTCGTGACTACACAGAGTTACTGGCACAAGTTTATCTTC
TTCCAGATTTCCTTTCAGAACACTCAAAGGTTCGACTAGTGATAGTGGATGGTATTGCTT
TTCCATTTCGTCATGACCTAGATGACCTGTCTCTTCGTACTCGNTT
Restriction Sites NotI-NotI |
ACCN NM_058216
Insert Size 2680 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_058216.1, NP_478123.1
RefSeq Size 1295 bp
RefSeq ORF 1131 bp
Locus ID 5889
UniProt ID O43502
Cytogenetics 17q22
Protein Families Druggable Genome
Protein Pathways Homologous recombination
Summary This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
Transcript Variant: This variant (1) is the longest transcript and encodes the longer isoform (1).
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Documents
Resources
"NM_058216" in other vectors (7)
SKU Description Size Price
RC210462 RAD51C (Myc-DDK-tagged)-Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1 10 ug
$686.00
RC210462L1 Lenti ORF clone of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1, Myc-DDK-tagged 10 ug
$986.00
RC210462L2 Lenti ORF clone of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1, mGFP tagged 10 ug
$986.00
RC210462L3 Lenti ORF clone of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1, Myc-DDK-tagged 10 ug
$986.00
RC210462L4 Lenti ORF clone of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1, mGFP tagged 10 ug
$986.00
RG210462 RAD51C (tGFP-tagged) - Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1 10 ug
$886.00
SC321013 RAD51C (untagged)-Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1 10 ug
$457.00

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