TRIM68 (NM_018073) Human Untagged Clone

SKU
SC108792
TRIM68 (untagged)-Human tripartite motif containing 68 (TRIM68)
  $732.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TRIM68
Synonyms GC109; RNF137; SS-56; SS56
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites SgfI-MluI |
ACCN NM_018073
Insert Size 1458 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_018073.7
RefSeq Size 3372 bp
RefSeq ORF 1458 bp
Locus ID 55128
UniProt ID Q6AZZ1
Cytogenetics 11p15.4
Domains RING, SPRY, zf-B_box
Protein Families Druggable Genome
MW 56.3 kDa
Summary This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2015
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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"NM_018073" in other vectors (6)
SKU Description Size Price
RC217536 TRIM68 (Myc-DDK-tagged)-Human tripartite motif containing 68 (TRIM68) 10 ug
$686.00
RC217536L1 Lenti ORF clone of Human tripartite motif containing 68 (TRIM68), Myc-DDK-tagged 10 ug
$986.00
RC217536L2 Lenti ORF clone of Human tripartite motif containing 68 (TRIM68), mGFP tagged 10 ug
$986.00
RC217536L3 Lenti ORF clone of Human tripartite motif containing 68 (TRIM68), Myc-DDK-tagged 10 ug
$986.00
RC217536L4 Lenti ORF clone of Human tripartite motif containing 68 (TRIM68), mGFP tagged 10 ug
$986.00
RG217536 TRIM68 (tGFP-tagged) - Human tripartite motif containing 68 (TRIM68) 10 ug
$886.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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