TIFA (NM_052864) Human Untagged Clone

SKU
SC107567
TIFA (untagged)-Human TRAF-interacting protein with forkhead-associated domain (TIFA)
  $300.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TIFA
Synonyms T2BP; T6BP; TIFAA
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC107567 sequence for NM_052864 edited (data generated by NextGen Sequencing)
ATGACCAGTTTTGAAGATGCTGACACAGAAGAGACAGTAACTTGTCTCCAGATGACGGTT
TACCATCCTGGCCAGTTGCAGTGTGGAATATTTCAGTCAATAAGTTTTAACAGAGAGAAA
CTCCCTTCCAGCGAAGTGGTGAAATTTGGCCGAAATTCCAACATCTGTCATTATACTTTT
CAGGACAAACAGGTTTCCCGAGTTCAGTTTTCTCTGCAGCTGTTTAAAAAATTCAACAGC
TCAGTTCTCTCCTTTGAAATAAAAAATATGAGTAAAAAGACCAATCTGATCGTGGACAGC
AGAGAGCTGGGCTACCTAAATAAAATGGACCTGCCATACAGGTGCATGGTCAGATTCGGA
GAGTATCAGTTTCTGATGGAGAAGGAAGATGGCGAGTCATTGGAATTTTTTGAGACTCAA
TTTATTTTATCTCCAAGATCACTCTTGCAAGAAAACAACTGGCCACCACACAGGCCCATA
CCGGAGTATGGCACTTACTCGCTCTGCTCCTCCCAAAGCAGTTCTCCGACAGAAATGGAT
GAAAATGAGTCATGA

Clone variation with respect to NM_052864.2
498 t=>c
5' Read Nucleotide Sequence
>OriGene 5' read for NM_052864 unedited
CCGGGCCCCCCNNNNNCCCCCCCCCCCGGTTCAGATTTGTATACGACTCCTATAGGCGGC
CGCGNAATTCGCACCAGGGAAGCAGGCCGCGCGCGCGGGAGCGCGGGAGGATCGGCGGCT
CGCGGTCACTGGTCCCTGGCTCGGTTCCCCGCACCCCGGGGCTCACACTTACCCGCGCGG
AGGAGCAGCGGCCGGGTGTCCACCCCCATCCTGCGCCCAGTCTCCTCGATTCCCCTCGCT
CTGAGCCGGGAGAGCCGAACAGCTGAAGAGAGTTCACTGACTCCCCAGCCCCAGGTGGGC
CTTGTGCACATCATGACCAGTTTTGAAGATGCTGACACAGAAGAGACAGTAACTTGTCTC
CAGATGACGGTTTACCATCCTGGCCAGTTGCAGTGTGGAATATTTCAGTCAATAAGTTTT
AACAGAGAGAAACTCCCTTCCAGCGAAGTGGTGAAATTTGGCCGAAATTCCAACATCTGT
CATTATACTTTTCAGGACAAACAGGNTTCCCGAGTTCAGTTNTCTCTGCAGCTGTTTAAA
AATTCAACAGCTCAGTTCTCTCCTTTGAANTANAAATATGAGTAANAAGACAATCTGATC
GTGGACAGCANAGAGCTGGGCTACCTAAATAAAATGGACCTGCCATACAGGTGCATGGNT
CAGATCGGAGAGTATCAGTTTCTGATGGAGAAGGAGATGGCGAGTCATTGGAATTTTTTG
AGACTCCATTTATTTTATCTCCCAGATCACTCTTGCAGAAAAACACTGGCCAACACACAG
GCCCATACCGGAGTTGGCACTTACTCGGTTTGCTCTCCCAAGCAGTTCTCCGAACGAAAT
GGATGAAATGAGTCCTGAACCCGAAAGTCTANAAGGAAAATTTGATGGATGAAAAGCTTT
GTAATGCTGATAGCACCTAAAATAGAGTGATAGGGGAGNATATTATAGCCATCTGTATGC
TGTGAAATTGGAATNCAAATTTGNAGCCTGAAAT
Restriction Sites NotI-NotI |
ACCN NM_052864
Insert Size 1750 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_052864.2, NP_443096.1
RefSeq Size 3090 bp
RefSeq ORF 555 bp
Locus ID 92610
UniProt ID Q96CG3
Cytogenetics 4q25
Summary This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. provided by RefSeq, Jun 2018
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Documents
Resources
"NM_052864" in other vectors (4)
SKU Description Size Price
RC204357 TIFA (Myc-DDK-tagged)-Human TRAF-interacting protein with forkhead-associated domain (TIFA) 10 ug
$300.00
RC204357L3 Lenti ORF clone of Human TRAF-interacting protein with forkhead-associated domain (TIFA), Myc-DDK-tagged 10 ug
$600.00
RC204357L4 Lenti ORF clone of Human TRAF-interacting protein with forkhead-associated domain (TIFA), mGFP tagged 10 ug
$600.00
RG204357 TIFA (tGFP-tagged) - Human TRAF-interacting protein with forkhead-associated domain (TIFA) 10 ug
$489.00 $500.00

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