DUSP18 (NM_152511) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | DUSP18 |
| Synonyms | DSP18; DUSP20; LMWDSP20 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_152511 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_152511.3, NP_689724.3 |
| RefSeq Size | 2453 bp |
| RefSeq ORF | 567 bp |
| Locus ID | 150290 |
| UniProt ID | Q8NEJ0 |
| Cytogenetics | 22q12.2 |
| Domains | DSPc |
| Protein Families | Druggable Genome, Phosphatase |
| Summary | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 PubMed 19228121).supplied by OMIM, Dec 2009 Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
"NM_152511" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC219496 | DUSP18 (Myc-DDK-tagged)-Human dual specificity phosphatase 18 (DUSP18) | 10 ug |
$300.00
|
|
| RC219496L3 | Lenti ORF clone of Human dual specificity phosphatase 18 (DUSP18), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC219496L4 | Lenti ORF clone of Human dual specificity phosphatase 18 (DUSP18), mGFP tagged | 10 ug |
$600.00
|
|
| RG219496 | DUSP18 (tGFP-tagged) - Human dual specificity phosphatase 18 (DUSP18) | 10 ug |
$489.00
$500.00
|
|
Citations
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