CHD4 (NM_001273) Human Tagged ORF Clone
$2,007.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | CHD4 |
| Synonyms | CHD-4; Mi-2b; Mi2-BETA; SIHIWES |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001273 |
| ORF Size | 5736 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001273.5 |
| RefSeq Size | 6511 bp |
| RefSeq ORF | 5739 bp |
| Locus ID | 1108 |
| UniProt ID | Q14839 |
| Cytogenetics | 12p13.31 |
| Domains | CHROMO, DEAD, helicase_C, PHD, SNF2_N |
| Protein Families | Druggable Genome, Transcription Factors |
| Summary | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2014 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001273" in other vectors (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC224232 | CHD4 (Myc-DDK-tagged)-Human chromodomain helicase DNA binding protein 4 (CHD4) | 10 ug |
$1,607.00
|
|
| RC224232L1 | Lenti ORF clone of Human chromodomain helicase DNA binding protein 4 (CHD4), Myc-DDK-tagged | 10 ug |
$1,907.00
|
|
| SC309882 | CHD4 (untagged)-Human chromodomain helicase DNA binding protein 4 (CHD4) | 10 ug |
$1,768.00
|
|
Citations
Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma
Nio, Yamashita, Okada et al
J. Hepatol. (2015)
Nio, Yamashita, Okada et al
J. Hepatol. (2015)
Cited by 100
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
