STRA6 (NM_001142617) Human Tagged ORF Clone
SKU
RC227393
STRA6 (Myc-DDK-tagged)-Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 1
$611.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | STRA6 |
| Synonyms | MCOPCB8; MCOPS9; PP14296 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001142617 |
| ORF Size | 2001 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001142617.1, NP_001136089.1 |
| RefSeq ORF | 2004 bp |
| Locus ID | 64220 |
| UniProt ID | Q9BX79, B3KPB8 |
| Cytogenetics | 15q24.1 |
| Protein Families | Transmembrane |
| MW | 73.3 kDa |
| Summary | The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. provided by RefSeq, Dec 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001142617" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC227393L3 | Lenti ORF clone of Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 1, Myc-DDK-tagged | 10 ug |
$911.00
|
|
| RC227393L4 | Lenti ORF clone of Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 1, mGFP tagged | 10 ug |
$911.00
|
|
| RG227393 | STRA6 (tGFP-tagged) - Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 1 | 10 ug |
$811.00
|
|
| SC325269 | STRA6 (untagged)-Human stimulated by retinoic acid gene 6 homolog (mouse) (STRA6), transcript variant 1 | 10 ug |
$612.00
|
|
Citations
Retinol from hepatic stellate cells via STRA6 induces lipogenesis on hepatocytes during fibrosis
Hwang, Lee, Park et al
Cell Biosci (2021) 11 (1), 3 DOI: 10.1186/s13578-020-00509-w
Hwang, Lee, Park et al
Cell Biosci (2021) 11 (1), 3 DOI: 10.1186/s13578-020-00509-w
Cited by 27
AI Summary: OriGene’s pCMV6-STRA6 plasmid (Cat. RC227393) was used in this study to investigate the role of STRA6 in retinol uptake and its contribution to lipogenesis and liver fibrosis.
Snippet: blocker GSK2033 (Cat. 5694/10) were purchased from R&D Systems. BODIPY (Cat. D3835, Thermo Fisher Scientific) was used to stain triglyceride in cells and tissues. The pCMV6-STRA6 was purchased from ORIGENE. (Cat. RC227393). Primary HSC culture The liver of a mouse was digested in situ as described previously [39]. The primary HSCs were isolated using the Nycodenz gradient method and incubated i
Showing 1-1 of 1 papers.
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