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PABPC4 (NM_001135653) Human Tagged ORF Clone

  • TrueORF®
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SKU
RC226744
PABPC4 (Myc-DDK-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
$289.00 $676.00
In Stock*
Bulk Requests & Clone Modifications

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Other products for "PABPC4 or NM_001135653"

Specifications
Specifications
Product Data
Type Human Tagged ORF Clone
Target Symbol PABPC4
Synonyms APP-1; APP1; iPABP; PABP4
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_001135653
ORF Size 1980 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001135653.1, NP_001129125.1
RefSeq ORF 1983 bp
Locus ID 8761
UniProt ID Q13310
Cytogenetics 1p34.3
MW 72.2 kDa
Summary Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2008
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"NM_001135653" in other vectors (4)
SKU Description Size Price
RC226744L3 Lenti-ORF clone of PABPC4 (Myc-DDK-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1 10 ug
$976.00
RC226744L4 Lenti-ORF clone of PABPC4 (mGFP-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1 10 ug
$976.00
RG226744 PABPC4 (tGFP-tagged) - Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1 10 ug
$489.00 $876.00
SC325261 PABPC4 (untagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 1 10 ug
$677.00

Plasmid Map for RC226744

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Cloning scheme for RC226744
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