BLOC1S1 (NM_001487) Human Tagged ORF Clone
SKU
RC224412
BLOC1S1 (Myc-DDK-tagged)-Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1
$150.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | BLOC1S1 |
| Synonyms | BLOS1; BORCS1; GCN5L1; MICoA; RT14 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001487 |
| ORF Size | 375 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001487.2 |
| RefSeq Size | 590 bp |
| RefSeq ORF | 462 bp |
| Locus ID | 2647 |
| UniProt ID | P78537 |
| Cytogenetics | 12q13.2 |
| MW | 14.3 kDa |
| Summary | BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 PubMed 15102850).supplied by OMIM, Mar 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001487" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC224412L1 | Lenti ORF clone of Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1, Myc-DDK-tagged | 10 ug |
$450.00
|
|
| RC224412L2 | Lenti ORF clone of Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1, mGFP tagged | 10 ug |
$450.00
|
|
| RC224412L3 | Lenti ORF clone of Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1, Myc-DDK-tagged | 10 ug |
$450.00
|
|
| RC224412L4 | Lenti ORF clone of Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1, mGFP tagged | 10 ug |
$450.00
|
|
| RG224412 | BLOC1S1 (tGFP-tagged) - Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1 | 10 ug |
$350.00
|
|
| SC303032 | BLOC1S1 (untagged)-Human biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1), transcript variant 1 | 10 ug |
$165.00
|
|
Citations
RhoB-Rab1A forms a mechanobiology module that couples cytoskeletal organization to nuclear mechanics and β-catenin access in epithelial cells
Li, Wang, Yu et al
Pathol Res Pract (2026) 281, 156406 DOI: 10.1016/j.prp.2026.156406
Li, Wang, Yu et al
Pathol Res Pract (2026) 281, 156406 DOI: 10.1016/j.prp.2026.156406
BLOC1S1 depletion via splice-switching oligonucleotides improves mitochondrial respiration and rescues ALS phenotypes
Hor, Ow, Ng et al
Mol Ther (2025)
Hor, Ow, Ng et al
Mol Ther (2025)
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
Le Thomas, Ferri, Marsters et al
Nat Commun (2021) 12 (1), 7310 DOI: 10.1038/s41467-021-27597-7
Le Thomas, Ferri, Marsters et al
Nat Commun (2021) 12 (1), 7310 DOI: 10.1038/s41467-021-27597-7
Cited by 78
AI Summary: In this study, OriGene’s BLOC1S1 (Cat# RC224412) and TNFAIP8L1 (Cat# RC203912) cDNA clones were used as templates to generate RNA substrates for investigating IRE1α-mediated mRNA decay mechanisms.
Snippet: UT), BCAM (#HG10238-UT), SNN (#HG23279-U), GBA (#HG12038-UT), WT1 (#HG12282-UT), CCDC69 (#HG27177-U), AIM2(#HG11654-UT) were from Sino Biological, and BLOC1S1 (#RC224412), TNFAIP8L1 (#RC203912) from Origene. cDNA was amplified using T7 forward primers, and subsequently in vitro transcribed using HiScribe T7 Quick High Yield RNA Synthesis Kit from NEB (#E2050S). T7 RNA mutations were engineere
Showing 1-3 of 3 papers.
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