MTMR3 (NM_021090) Human Tagged ORF Clone

  • TrueORF®
SKU
RC222287
MTMR3 (Myc-DDK-tagged)-Human myotubularin related protein 3 (MTMR3), transcript variant 3
  $1,564.00
In Stock*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone
Target Symbol MTMR3
Synonyms FYVE-DSP1; ZFYVE10
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_021090
ORF Size 3594 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_021090.4
RefSeq Size 5963 bp
RefSeq ORF 3597 bp
Locus ID 8897
UniProt ID Q13615
Cytogenetics 22q12.2
Domains FYVE, PTPc_motif
Protein Families Druggable Genome, Phosphatase
MW 133.4 kDa
Summary This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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"NM_021090" in other vectors (4)
SKU Description Size Price
RC222287L3 Lenti-ORF clone of MTMR3 (Myc-DDK-tagged)-Human myotubularin related protein 3 (MTMR3), transcript variant 3 10 ug
$1,864.00
RC222287L4 Lenti-ORF clone of MTMR3 (mGFP-tagged)-Human myotubularin related protein 3 (MTMR3), transcript variant 3 10 ug
$1,864.00
RG222287 MTMR3 (tGFP-tagged) - Human myotubularin related protein 3 (MTMR3), transcript variant 3 10 ug
$1,764.00
SC111723 MTMR3 (untagged)-Human myotubularin related protein 3 (MTMR3), transcript variant 3 10 ug
$1,565.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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