Nurr1 (NR4A2) (NM_006186) Human Tagged ORF Clone
- TrueORF®
SKU
RC221280
NR4A2 (Myc-DDK-tagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2)
$890.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | Nurr1 |
| Synonyms | HZF-3; NOT; NURR1; RNR1; TINUR |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites | SgfI-RsrII Cloning Scheme for this gene | |
| ACCN | NM_006186 |
| ORF Size | 1794 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_006186.4 |
| RefSeq Size | 3447 bp |
| RefSeq ORF | 1797 bp |
| Locus ID | 4929 |
| UniProt ID | P43354 |
| Cytogenetics | 2q24.1 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| MW | 66.4 kDa |
| Summary | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_006186" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC221280L1 | Lenti-ORF clone of NR4A2 (Myc-DDK-tagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,190.00
|
|
| RC221280L2 | Lenti-ORF clone of NR4A2 (mGFP-tagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,190.00
|
|
| RC221280L3 | Lenti-ORF clone of NR4A2 (Myc-DDK-tagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,190.00
|
|
| RC221280L4 | Lenti-ORF clone of NR4A2 (mGFP-tagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,190.00
|
|
| RG221280 | NR4A2 (tGFP-tagged) - Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,090.00
|
|
| SC116298 | NR4A2 (untagged)-Human nuclear receptor subfamily 4, group A, member 2 (NR4A2) | 10 ug |
$1,543.00
|
|
Citations
Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery
Azimi, Sheridan, Ghannad-Rezaie et al
Elife (2018) 7 DOI: 10.7554/eLife.31922
Azimi, Sheridan, Ghannad-Rezaie et al
Elife (2018) 7 DOI: 10.7554/eLife.31922
AI Summary: OriGene’s pCMV6 cDNA clones for OTX2, LMX1A, FOXA2, ASCL1, NGN2, NURR1, PITX3, EGFP, and mCherry were used as templates to generate mRNAs for combinatorial transcription factor delivery in neural progenitor cell differentiation experiments.
Snippet: has been previously described (Angel and Yanik, 2010). Briefly, dsDNA templates were linearized from cDNA clones in pCMV6 vectors for OTX2, LMX1A, FOXA2, ASCL1, NGN2, NURR1, PITX3, EGFP, and mCherry (OriGene, Rockville, MD). To maximize the stability of mRNA transcripts and increase protein translation, we added 5’ and 3’ untranslated regions from human Beta-globin gene (Hbb) to the templates
Showing 1-1 of 1 papers.
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