ABCC10 (NM_033450) Human Tagged ORF Clone
SKU
RC221247
ABCC10 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (ABCC10), transcript variant MRP7A
$1,252.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | ABCC10 |
| Synonyms | EST182763; MRP7; SIMRP7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_033450 |
| ORF Size | 4392 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_033450.2, NP_258261.2 |
| RefSeq Size | 5118 bp |
| RefSeq ORF | 4395 bp |
| Locus ID | 89845 |
| UniProt ID | Q5T3U5 |
| Cytogenetics | 6p21.1 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters |
| MW | 158.6 kDa |
| Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Nov 2010 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_033450" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC221247L3 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (ABCC10), transcript variant MRP7A, Myc-DDK-tagged | 10 ug |
$1,552.00
|
|
| RC221247L4 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (ABCC10), transcript variant MRP7A, mGFP tagged | 10 ug |
$1,552.00
|
|
| RG221247 | ABCC10 (tGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (ABCC10), transcript variant MRP7A | 10 ug |
$1,452.00
|
|
| SC305638 | ABCC10 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (ABCC10), transcript variant MRP7A | 10 ug |
$1,378.00
|
|
Citations
A Novel miR-98 Negatively Regulates the Resistance of Endometrial Cancer Cells to Paclitaxel by Suppressing ABCC10/MRP-7
Huang, Zhang, Dong et al
Front Oncol (2021) 11, 809410 DOI: 10.3389/fonc.2021.809410
Huang, Zhang, Dong et al
Front Oncol (2021) 11, 809410 DOI: 10.3389/fonc.2021.809410
Cited by 21
AI Summary: OriGene's pCMV6-MRP-7 plasmid (RC221247) was used to overexpress MRP-7 in RL95 endometrial cancer cells, enabling the study of its role in paclitaxel resistance.
Snippet: RL95 cells were transfected with pCMV6-MRP-7 (RC221247, OriGene, Rockville, MD, USA)
Showing 1-1 of 1 papers.
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