FBXO44 (NM_033182) Human Tagged ORF Clone
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | FBXO44 |
| Synonyms | FBG3; FBX6A; FBX30; Fbx44; Fbxo6a |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_033182 |
| ORF Size | 765 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_033182.7 |
| RefSeq Size | 2948 bp |
| RefSeq ORF | 768 bp |
| Locus ID | 93611 |
| UniProt ID | Q9H4M3, A0A024R4F9 |
| Cytogenetics | 1p36.22 |
| Domains | F-box, FBA |
| Protein Families | Druggable Genome |
| MW | 29.6 kDa |
| Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. provided by RefSeq, Feb 2015 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_033182" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC216126L1 | Lenti ORF clone of Human F-box protein 44 (FBXO44), transcript variant 1, Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC216126L2 | Lenti ORF clone of Human F-box protein 44 (FBXO44), transcript variant 1, mGFP tagged | 10 ug |
$600.00
|
|
| RC216126L3 | Lenti ORF clone of Human F-box protein 44 (FBXO44), transcript variant 1, Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC216126L4 | Lenti ORF clone of Human F-box protein 44 (FBXO44), transcript variant 1, mGFP tagged | 10 ug |
$600.00
|
|
| RG216126 | FBXO44 (tGFP-tagged) - Human F-box protein 44 (FBXO44), transcript variant 1 | 10 ug |
$489.00
$500.00
|
|
| SC311243 | FBXO44 (untagged)-Human F-box protein 44 (FBXO44), transcript variant 1 | 10 ug |
$300.00
|
|
Citations
A p53-dependent FBXO44-RAD18 axis limits mutagenesis by terminating translesion DNA synthesis
Butera, Caporali, Capradossi et al
bioRxiv (2026)
Butera, Caporali, Capradossi et al
bioRxiv (2026)
E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia
Benini, Fortuni, Condò et al
Cell Rep (2017) 18 (8), 2007-2017 DOI: 10.1016/j.celrep.2017.01.079
Benini, Fortuni, Condò et al
Cell Rep (2017) 18 (8), 2007-2017 DOI: 10.1016/j.celrep.2017.01.079
The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation
Lu, Li, Cheng et al
J. Biol. Chem. (2012) 287 (49), 41014-22 DOI: 10.1074/jbc.M112.407106
Lu, Li, Cheng et al
J. Biol. Chem. (2012) 287 (49), 41014-22 DOI: 10.1074/jbc.M112.407106
Showing 1-3 of 3 papers.
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