RED (IK) (NM_006083) Human Tagged ORF Clone
$778.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | RED |
| Synonyms | CSA2; RED; RER |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_006083 |
| ORF Size | 1671 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_006083.4 |
| RefSeq Size | 1955 bp |
| RefSeq ORF | 1674 bp |
| Locus ID | 3550 |
| UniProt ID | Q13123 |
| Cytogenetics | 5q31.3 |
| Protein Families | Druggable Genome |
| MW | 65.6 kDa |
| Summary | The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_006083" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC201246L1 | Lenti-ORF clone of IK (Myc-DDK-tagged)-Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$1,078.00
|
|
| RC201246L2 | Lenti-ORF clone of IK (mGFP-tagged)-Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$1,078.00
|
|
| RC201246L3 | Lenti-ORF clone of IK (Myc-DDK-tagged)-Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$1,078.00
|
|
| RC201246L4 | Lenti-ORF clone of IK (mGFP-tagged)-Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$1,078.00
|
|
| RG201246 | IK (tGFP-tagged) - Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$978.00
|
|
| SC116310 | IK (untagged)-Human IK cytokine, down-regulator of HLA II (IK) | 10 ug |
$519.00
|
|
Citations
Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA
Ka, Lee, Han et al
Cell Death Discov (2020) 6, 34 DOI: 10.1038/s41420-020-0268-1
Ka, Lee, Han et al
Cell Death Discov (2020) 6, 34 DOI: 10.1038/s41420-020-0268-1
Cited by 43
AI Summary: OriGene products contributed to this study by providing full-length human IK and USP47 cDNAs, as well as full-length mouse IK cDNA, which were used for plasmid construction and functional assays to investigate the roles of IK and USP47 in ATM pre-mRNA splicing and protein stabilization.
Snippet: … Full-length human IK and USP47 cDNAs were purchased from OriGene (OriGene Technologies, Inc., Rockville, MD) and cloned into pcDNA 3.1, pcDNA 3.0, and pCMV-tag-2B vectors. In the restoration assay, IK cloned into pCMV-tag-2B vector was used;Full-length human IK and USP47 cDNAs were purchased from OriGene (OriGene Technologies, Inc., Rockville, MD) and cloned into pcDNA 3.1, pcDNA 3.0, and pCMV-tag-2B vectors. …
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
