Esrra (NM_007953) Mouse Tagged ORF Clone
$686.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Esrra |
| Synonyms | Err1; ERRalpha; Estrra; Nr3b1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_007953 |
| ORF Size | 1266 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_007953.2, NP_031979.2 |
| RefSeq Size | 2264 bp |
| RefSeq ORF | 1269 bp |
| Locus ID | 26379 |
| UniProt ID | O08580 |
| Cytogenetics | 19 5.08 cM |
| MW | 45.5 kDa |
| Summary | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_007953" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC209715 | Esrra (untagged) - Mouse estrogen related receptor, alpha (Esrra), (10ug) | 10 ug |
$457.00
|
|
| MG225753 | Esrra (tGFP-tagged) - Mouse estrogen related receptor alpha (Esrra), (10ug) | 10 ug |
$886.00
|
|
| MR225753L1 | Lenti ORF clone of Esrra (Myc-DDK-tagged) - Mouse estrogen related receptor, alpha (Esrra) | 10 ug |
$986.00
|
|
| MR225753L2 | Lenti ORF clone of Esrra (mGFP-tagged) - Mouse estrogen related receptor, alpha (Esrra) | 10 ug |
$986.00
|
|
| MR225753L3 | Lenti ORF clone of Esrra (Myc-DDK-tagged) - Mouse estrogen related receptor, alpha (Esrra) | 10 ug |
$986.00
|
|
| MR225753L4 | Lenti ORF clone of Esrra (mGFP-tagged) - Mouse estrogen related receptor, alpha (Esrra) | 10 ug |
$986.00
|
|
Citations
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Shamsi, Xue, Huang et al
Nat Commun (2020) 11 (1), 1421 DOI: 10.1038/s41467-020-15055-9
Shamsi, Xue, Huang et al
Nat Commun (2020) 11 (1), 1421 DOI: 10.1038/s41467-020-15055-9
Cited by 120
AI Summary: OriGene’s mouse Fgf6 and Fgf9 cDNA clones were used to generate expression constructs that enabled the study of how these growth factors regulate UCP1 expression in adipocytes.
Snippet: CBA promoter in the pAAV-CBA-W backbone with the human Adiponectin enhancer and promoter sequences (pAAV-hAdiponectin-W). Mouse Fgf6 and Fgf9 complementary DNAs (cDNAs) were cloned from cDNA clones (Origene). Gfp cDNA was derived from pLenti-GFP-Blast (Addgene, plasmid #17445). The pAAV-hAdiponectin-W backbone was linearized using SpeI/NotI (for Fgf6) or XhoI/NotI (for Fgf9 and Gfp) and ligated w
Showing 1-1 of 1 papers.
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