Sbno2 (NM_183426) Mouse Tagged ORF Clone
- TrueORF®
SKU
MR211942
Sbno2 (Myc-DDK-tagged) - Mouse strawberry notch homolog 2 (Drosophila) (Sbno2)
$589.00
$1,154.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Sbno2 |
| Synonyms | BC019206; F730040C21; Sno; Stno |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_183426 |
| ORF Size | 4047 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_183426.2 |
| RefSeq Size | 4679 bp |
| RefSeq ORF | 4050 bp |
| Locus ID | 216161 |
| UniProt ID | Q7TNB8 |
| Cytogenetics | 10 C1 |
| MW | 149.7 kDa |
| Summary | Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions (PubMed:18025162, PubMed:23980096). Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast (PubMed:23980096). Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway (PubMed:23980096). May also be required in the regulation of osteoblast differentiation (PubMed:23980096). Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_183426" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC224296 | Sbno2 (untagged) - Mouse strawberry notch homolog 2 (Drosophila) (Sbno2), (10ug) | 10 ug |
$1,270.00
|
|
| MG211942 | Sbno2 (tGFP-tagged) - Mouse strawberry notch homolog 2 (Drosophila) (Sbno2) | 10 ug |
$489.00
$1,354.00
|
|
| MR211942L3 | Lenti ORF clone of Sbno2 (Myc-DDK-tagged) - Mouse strawberry notch homolog 2 (Drosophila) (Sbno2) | 10 ug |
$1,454.00
|
|
| MR211942L4 | Lenti ORF clone of Sbno2 (mGFP-tagged) - Mouse strawberry notch homolog 2 (Drosophila) (Sbno2) | 10 ug |
$1,454.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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