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Rtn4r (NM_022982) Mouse Tagged ORF Clone

  • TrueORF®
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SKU
MR207571
Rtn4r (Myc-DDK-tagged) - Mouse reticulon 4 receptor (Rtn4r)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
$289.00 $457.00
In Stock*
Bulk Requests & Clone Modifications

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Other products for "Rtn4r or NM_022982"

Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Rtn4r
Synonyms NgR; NgR1; NOGOR
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MR207571 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAAGAGGGCGTCCTCCGGAGGAAGCAGGCTGCTGGCATGGGTGTTATGGCTACAGGCCTGGAGGGTAG
CAACACCATGCCCTGGTGCTTGTGTGTGCTACAATGAGCCCAAGGTAACAACAAGCTGCCCCCAGCAGGG
TCTGCAGGCTGTGCCCACTGGCATCCCAGCCTCTAGCCAGCGAATCTTCCTGCATGGCAACCGAATCTCT
CACGTGCCAGCTGCGAGCTTCCAGTCATGCCGAAATCTCACTATCCTGTGGCTGCACTCTAATGCGCTGG
CTCGGATCGATGCTGCTGCCTTCACTGGTCTGACCCTCCTGGAGCAACTAGATCTTAGTGATAATGCACA
GCTTCATGTCGTGGACCCTACCACGTTCCACGGCCTGGGCCACCTGCACACACTGCACCTAGACCGATGT
GGCCTGCGGGAGCTGGGTCCCGGCCTATTCCGTGGACTAGCAGCTCTGCAGTACCTCTACCTACAAGACA
ACAATCTGCAGGCACTCCCTGACAACACCTTTCGAGACCTGGGCAACCTCACGCATCTCTTTCTGCATGG
CAACCGTATCCCCAGTGTGCCTGAGCACGCTTTCCGTGGCCTGCACAGTCTTGACCGCCTCCTCTTGCAC
CAGAACCATGTGGCTCGTGTGCACCCACATGCCTTCCGGGACCTTGGCCGCCTCATGACCCTCTACCTGT
TTGCCAACAACCTCTCCATGCTGCCTGCAGAGGTCCTAATGCCCCTGAGGTCTCTGCAGTACCTGCGACT
CAATGACAACCCCTGGGTGTGTGACTGCCGGGCACGTCCACTCTGGGCCTGGCTGCAGAAGTTCCGAGGT
TCCTCATCAGAGGTGCCCTGCAACCTGCCCCAACGCCTGGCAGACCGTGATCTTAAGCGCCTCGCTGCCA
GTGACCTAGAGGGCTGTGCTGTGGCTTCAGGACCCTTCCGTCCCATCCAGACCAGTCAGCTCACTGATGA
GGAGCTGCTGAGCCTCCCCAAGTGCTGCCAGCCAGATGCTGCAGACAAAGCCTCAGTACTGGAACCCGGG
AGGCCAGCTTCTGCCGGAAACGCCCTCAAGGGACGTGTGCCTCCCGGTGACACTCCACCAGGCAATGGCT
CAGGCCCTCGGCACATCAATGACTCTCCATTTGGAACTTTGCCCAGCTCTGCAGAGCCCCCACTGACTGC
CCTGCGGCCTGGGGGTTCCGAGCCACCAGGACTTCCCACCACTGGTCCCCGCAGGAGGCCAGGTTGTTCC
CGGAAGAATCGCACCCGCAGCCACTGCCGTCTGGGCCAGGCGGGAAGTGGGGCCAGTGGAACAGGGGACG
CAGAGGGTTCAGGGGCTCTGCCTGCTCTGGCCTGCAGCCTTGCTCCTCTGGGCCTTGCACTGGTACTTTG
GACAGTGCTTGGGCCCTGC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Protein Sequence
>MR207571 protein sequence
Red=Cloning site Green=Tags(s)

MKRASSGGSRLLAWVLWLQAWRVATPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRIS
HVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRC
GLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLH
QNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRG
SSSEVPCNLPQRLADRDLKRLAASDLEGCAVASGPFRPIQTSQLTDEELLSLPKCCQPDAADKASVLEPG
RPASAGNALKGRVPPGDTPPGNGSGPRHINDSPFGTLPSSAEPPLTALRPGGSEPPGLPTTGPRRRPGCS
RKNRTRSHCRLGQAGSGASGTGDAEGSGALPALACSLAPLGLALVLWTVLGPC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_022982
ORF Size 1419 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_022982.3
RefSeq Size 1890 bp
RefSeq ORF 1422 bp
Locus ID 65079
UniProt ID Q99PI8
Cytogenetics 16 A3
MW 51 kDa
Summary Receptor for RTN4, OMG and MAG (PubMed:11201742, PubMed:12089450, PubMed:15504325, PubMed:18411262, PubMed:22923615). Functions as receptor for the sialylated gangliosides GT1b and GM1 (PubMed:18411262). Besides, functions as receptor for chondroitin sulfate proteoglycans (PubMed:22406547). Can also bind heparin (PubMed:22406547). Intracellular signaling cascades are triggered via the coreceptor NGFR (By similarity). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200). Mediates axonal growth inhibition (By similarity). Mediates axonal growth inhibition and plays a role in regulating axon regeneration and neuronal plasticity in the adult central nervous system (PubMed:11201742, PubMed:12089450, PubMed:15504325, PubMed:22923615). Plays a role in postnatal brain development (PubMed:27339102). Required for normal axon migration across the brain midline and normal formation of the corpus callosum (PubMed:27339102). Protects motoneurons against apoptosis; protection against apoptosis is probably mediated via interaction with MAG (PubMed:26335717). Acts in conjunction with RTN4 and LINGO1 in regulating neuronal precursor cell motility during cortical development (PubMed:20093372). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200).UniProtKB/Swiss-Prot Function
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"NM_022982" in other vectors (4)
SKU Description Size Price
MC205180 Rtn4r (untagged) - Mouse reticulon 4 receptor (Rtn4r), (10ug) 10 ug
$457.00
MG207571 Rtn4r (tGFP-tagged) - Mouse reticulon 4 receptor (Rtn4r) 10 ug
$657.00
MR207571L3 Lenti ORF clone of Rtn4r (Myc-DDK-tagged) - Mouse reticulon 4 receptor (Rtn4r) 10 ug
$757.00
MR207571L4 Lenti ORF clone of Rtn4r (mGFP-tagged) - Mouse reticulon 4 receptor (Rtn4r) 10 ug
$757.00

Plasmid Map for MR207571

Download sequence for

file-download TXT (FASTA format)

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Cloning scheme for MR207571
Circular map for MR207571

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