OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Cavin2 (NM_138741) Mouse Tagged ORF Clone

  • TrueORF®
Be the first to review this product
SKU
MG206626
Sdpr (tGFP-tagged) - Mouse serum deprivation response (Sdpr)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
tGFP DDK
AAV Particle:
DDK
  $657.00
3 Weeks*
Bulk Requests & Clone Modifications

Frequently Bought Together (5)

TA339682 Rabbit Polyclonal Anti-Sdpr Antibody
100 ul
$585.00
TA150041 Mouse monoclonal turboGFP antibody, clone OTI2H8 100 ul
$447.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
PS100010 pCMV6-AC-GFP, mammalian vector with C-terminal tGFP tag, 10ug
10 ug
$780.00

Other products for "Cavin2 or NM_138741"

Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Cavin2
Synonyms Sdpr
Vector pCMV6-AC-GFP
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MG206626 representing NM_138741
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGAGAGGACGCTGCACAGGCAGAAAAGTTCCAGCATCCAAACACAGACATGCTCCAGGAGAAGCCAT
CCAGCCCCAGCCCAATGCCTTCCTCCACACCGAGCCCCAGCCTGAACCTGGGGTCCACAGAGGAGGCCAT
CCGAGACAACTCGCAGGTGAATGCTGTCACCGTGCACACACTCCTGGATAAATTGGTCAACATGCTGGAC
GCCGTGAGGGAGAACCAGCACAACATGGAACAGCGTCAGATCAACCTGGAGGGCTCGGTGAAGGGCATCC
AGAACGACCTCACCAAGCTCTCCAAGTACCAGGCCTCCACCAGCAACACAGTGAGCAAGCTGCTAGAGAA
GTCTCGCAAGGTCAGCGCTCACACGCGGGCTGTCCGGGAGCGCCTCGAGAGGCAGTGTGTCCAGGTGAAG
AGACTGGAGAACAACCACGCCCAACTCCTCCGACGCAACCACTTCAAAGTGCTCATCTTCCAGGAAGAAA
GTGAGATCCCTGCCAGTGTGTTTGTGAAGGAGCCAGTTCCCAGCGCTGCAGAAGGCAAGGAGGAGCTTGC
TGATGAGAACAAGTCCCTGGAGGAAACTCTGCACAACGTGGACCTCTCCTCTGATGACGAATTGCCCCGT
GATGAGGAAGCCCTGGAAGATAGTGCAGAAGAGAAGATGGAAGAAAGCAGGGCAGAAAAAATAAAAAGAT
CCAGCCTCAAGAAAGTCGATAGCCTCAAGAAAGCGTTTTCTCGTCAGAACATCGAGAAAAAGATGAACAA
GCTGGGAACCAAGATCGTATCTGTTGAGAGGAGAGAAAAGATTAAGAAATCGCTCACACCCAACCACCAG
AAAGCATCTTCTGGGAAAAGCTCCCCCTTCAAGGTTTCTCCCCTCTCCTTTGGTCGTAAGAAAGTCCGAG
AGGGAGAAAGCTCTGTAGAAAATGAGACCAAGTTGGAAGACCAGATGCAGGAGGACCGCGAGGAGGGTTC
GTTCACAGAGGGTCTTTCTGAAGCATCCCTCCCCAGTGGCCTGATGGAGGGCAGCGCAGAAGATGCTGAG
AAATCAGCAAGGAGAGGGAACAACTCAGCCGTGGGCAGTAATGCGGATCTGACCATTGAGGAAGATGAAG
AAGAGGAGCCGGTAGCCCTGCAGCAGGCCCAGCAGGTGCGCTATGAGAGTGGCTACATGCTCAACTCCGA
GGAGATGGAGGAACCCAGTGAGAAACAGGTCCAGCCAGCTGTGCTGCATGTGGATCAGACTGCC

ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
Protein Sequence
>MG206626 representing NM_138741
Red=Cloning site Green=Tags(s)

MGEDAAQAEKFQHPNTDMLQEKPSSPSPMPSSTPSPSLNLGSTEEAIRDNSQVNAVTVHTLLDKLVNMLD
AVRENQHNMEQRQINLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVRERLERQCVQVK
RLENNHAQLLRRNHFKVLIFQEESEIPASVFVKEPVPSAAEGKEELADENKSLEETLHNVDLSSDDELPR
DEEALEDSAEEKMEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTPNHQ
KASSGKSSPFKVSPLSFGRKKVREGESSVENETKLEDQMQEDREEGSFTEGLSEASLPSGLMEGSAEDAE
KSARRGNNSAVGSNADLTIEEDEEEEPVALQQAQQVRYESGYMLNSEEMEEPSEKQVQPAVLHVDQTA

TRTRPLE - GFP Tag - V
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_138741
ORF Size 1254 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_138741.1, NP_620080.1
RefSeq Size 3069 bp
RefSeq ORF 1257 bp
Locus ID 20324
UniProt ID Q63918
Cytogenetics 1 C1.1
Summary Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (By similarity). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells (PubMed:23652019). May play a role in targeting PRKCA to caveolae (By similarity).UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_138741" in other vectors (4)
SKU Description Size Price
MC205795 Sdpr (untagged) - Mouse serum deprivation response (Sdpr), (10ug) 10 ug
$457.00
MR206626 Sdpr (Myc-DDK-tagged) - Mouse serum deprivation response (Sdpr) 10 ug
$289.00 $457.00
MR206626L3 Lenti ORF clone of Sdpr (Myc-DDK-tagged) - Mouse serum deprivation response (Sdpr) 10 ug
$757.00
MR206626L4 Lenti ORF clone of Sdpr (mGFP-tagged) - Mouse serum deprivation response (Sdpr) 10 ug
$757.00

Plasmid Map for MG206626

Download sequence for

file-download TXT (FASTA format)

file-download Genbank

Cloning scheme for MG206626
Circular map for MG206626

file-alt Citations

CAVIN2 is frequently silenced by CpG methylation and sensitizes lung cancer cells to paclitaxel and 5-FU
Peng, Ye, Yang et al
Epigenomics (2020) 12 (20), 1793-1810 DOI: 10.2217/epi-2020-0157
Cited by 7
AI Summary: OriGene’s CAVIN2 cDNA clone (catalog # RC202232) was used in this study to ectopically express CAVIN2 in lung cancer cells, enabling the authors to investigate the tumor suppressor function of CAVIN2 and its role in sensitizing cells to paclitaxel and 5-fluorouracil.
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products