Adgrb1 (NM_174991) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Adgrb1 |
| Synonyms | B830018M07Rik; Bai1; mKIAA4089; R75078 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_174991 |
| Insert Size | 4749 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_174991.3, NP_778156.2 |
| RefSeq Size | 6227 bp |
| RefSeq ORF | 4749 bp |
| Locus ID | 107831 |
| UniProt ID | Q3UHD1 |
| Cytogenetics | 15 D3 |
| Summary | Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:17960134). Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:21245295, PubMed:26838550, PubMed:26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (By similarity). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (By similarity). Promotes myoblast fusion (PubMed:23615608). Activates the Rho pathway in a G-protein-dependent manner (By similarity). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (PubMed:25751059). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (By similarity).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) encodes the longer isoform (1). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_174991" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG215473 | Bai1 (tGFP-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1), (10ug) | 10 ug |
$2,229.00
|
|
| MR215473 | Bai1 (Myc-DDK-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1) | 10 ug |
$2,029.00
|
|
| MR215473L3 | Lenti ORF clone of Bai1 (Myc-DDK-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1) | 10 ug |
$2,329.00
|
|
| MR215473L4 | Lenti ORF clone of Bai1 (mGFP-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1) | 10 ug |
$2,329.00
|
|