Astn2 (NM_207109) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Astn2 |
| Synonyms | 1d8; Astnl; bM452J22.1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_207109 |
| Insert Size | 4059 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_207109.2, NP_996992.1 |
| RefSeq Size | 4831 bp |
| RefSeq ORF | 4059 bp |
| Locus ID | 56079 |
| UniProt ID | Q80Z10 |
| Cytogenetics | 4 C1 |
| Summary | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (PubMed:20573900). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (By similarity).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (2) represents the longer transcript and it encodes the longer isoform (b). Isoform b is most similar to the protein encoded by transcript variant 3 of the human gene. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Reviews
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"NM_207109" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG223105 | Astn2 (tGFP-tagged) - Mouse astrotactin 2 (Astn2) transcript variant 2, (10ug) | 10 ug |
$1,356.00
|
|
| MR223105 | Astn2 (Myc-DDK-tagged) - Mouse astrotactin 2 (Astn2), transcript variant 2 | 10 ug |
$589.00
$1,156.00
|
|
| MR223105L3 | Lenti ORF clone of Astn2 (Myc-DDK-tagged) - Mouse astrotactin 2 (Astn2), transcript variant 2 | 10 ug |
$1,456.00
|
|
| MR223105L4 | Lenti ORF clone of Astn2 (mGFP-tagged) - Mouse astrotactin 2 (Astn2), transcript variant 2 | 10 ug |
$1,456.00
|
|
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